Rare mutations implicate CGE interneurons as a vulnerable axis of cognitive deficits across psychiatric disorders

Posted by klaurent Columbia

Kavli Affiliate: Attila Losonczy | Authors: Stephanie A Herrlinger, Jiayao Wang, Bovey Y Rao, Jonathan Chang, Joseph Gogos, Attila Losonczy and Dennis Vitkup | Summary: Neuropsychiatric disorders such as autism spectrum disorder (ASD) and schizophrenia (SCZ) share genetic risk factors, including rare high penetrance single nucleotide variants and copy number variants (CNVs), and exhibit both […]


Continue.. Rare mutations implicate CGE interneurons as a vulnerable axis of cognitive deficits across psychiatric disorders

Multi-color characterization of optically invisible FU Orionis-type outbursts: Demonstration and prospects for the WINTER survey

Posted by klaurent MIT

Kavli Affiliate: Robert Simcoe | Summary:Episodic mass accretion is the dominant mechanism for mass assembly in the proto-stellar phase. Although prior optical time-domain searches have allowed detailed studies of individual outbursts, these searches remain insensitive to the earliest stages of star formation. In this paper, we present the characterization of two FU Orionis (FUor) outbursts […]


Continue.. Multi-color characterization of optically invisible FU Orionis-type outbursts: Demonstration and prospects for the WINTER survey

Multi-color characterization of optically invisible FU Orionis-type outbursts: Demonstration and prospects for the WINTER survey

Posted by klaurent MIT

Kavli Affiliate: Nathan P. Lourie| First 5 Authors: Danielle Frostig, Danielle Frostig, , , | Summary:Episodic mass accretion is the dominant mechanism for mass assembly in the proto-stellar phase. Although prior optical time-domain searches have allowed detailed studies of individual outbursts, these searches remain insensitive to the earliest stages of star formation. In this paper, […]


Continue.. Multi-color characterization of optically invisible FU Orionis-type outbursts: Demonstration and prospects for the WINTER survey

Multi-color characterization of optically invisible FU Orionis-type outbursts: Demonstration and prospects for the WINTER survey

Posted by klaurent MIT

Kavli Affiliate: Robert A. Simcoe | First 5 Authors: Danielle Frostig, Danielle Frostig, , , | Summary: Episodic mass accretion is the dominant mechanism for mass assembly in the proto-stellar phase. Although prior optical time-domain searches have allowed detailed studies of individual outbursts, these searches remain insensitive to the earliest stages of star formation. In […]


Continue.. Multi-color characterization of optically invisible FU Orionis-type outbursts: Demonstration and prospects for the WINTER survey

A carbon-rich atmosphere on a windy pulsar planet

Posted by klaurent Stanford

Kavli Affiliate: Roger Romani | Summary:A handful of enigmatic Jupiter-mass objects have been discovered orbiting pulsars. One such object, PSR,J2322-2650b, uniquely resembles a hot Jupiter exoplanet due to its minimum density of 1.8 g/cm^3 and its ~1900 K equilibrium temperature. We use JWST to observe PSR J2322-2650b’s emission spectrum across an entire orbit. In stark […]


Continue.. A carbon-rich atmosphere on a windy pulsar planet

A carbon-rich atmosphere on a windy pulsar planet

Posted by klaurent Stanford

Kavli Affiliate: Roger Romani| First 5 Authors: Michael Zhang, Michael Zhang, , , | Summary:A handful of enigmatic Jupiter-mass objects have been discovered orbiting pulsars. One such object, PSR J2322-2650b, uniquely resembles a hot Jupiter exoplanet due to its minimum density of 1.8 g/cm^3 and its ~1900 K equilibrium temperature. We use JWST to observe […]


Continue.. A carbon-rich atmosphere on a windy pulsar planet

A carbon-rich atmosphere on a windy pulsar planet

Posted by klaurent Stanford

Kavli Affiliate: Roger W. Romani | First 5 Authors: Michael Zhang, Michael Zhang, , , | Summary: A handful of enigmatic Jupiter-mass objects have been discovered orbiting pulsars. One such object, PSR J2322-2650b, uniquely resembles a hot Jupiter exoplanet due to its minimum density of 1.8 g/cm^3 and its ~1900 K equilibrium temperature. We use […]


Continue.. A carbon-rich atmosphere on a windy pulsar planet

Disentangling Multiple Gas Kinematic Drivers in the Perseus Galaxy Cluster

Posted by klaurent MIT

Kavli Affiliate: Erin Kara | Summary:Galaxy clusters, the Universe’s largest halo structures, are filled with 10-100 million degree X-ray-emitting gas. Their evolution is shaped by energetic processes such as feedback from supermassive black holes (SMBHs) and mergers with other cosmic structures. The imprints of these processes on gas kinematic properties remain largely unknown, restricting our […]


Continue.. Disentangling Multiple Gas Kinematic Drivers in the Perseus Galaxy Cluster

Calorie Restriction modulates beta cell IP3R activity to regulate Ca2+ homeostasis and cell network connectivity

Posted by dbos UCSD / Salk

Kavli Affiliate: Mark Ellisman | Authors: Johannes Pfabe, Cristiane dos Santos, Melanie Cutler, Christopher Acree, Aliyah Habashy, Amanda Cambraia, Guy Perkins, Mark Ellisman, Marjan Slak Rupnik and Rafael Arrojo e Drigo | Summary: Calorie restriction (CR) promotes beta cell longevity by regulating cell identity, organelle and protein homeostasis, and metabolism pathways. CR beta cells have […]


Continue.. Calorie Restriction modulates beta cell IP3R activity to regulate Ca2+ homeostasis and cell network connectivity

Optical Fiber-Waveguide Hybrid Architecture for Mid-Infrared Ring Lasers

Posted by klaurent UCAS

Kavli Affiliate: Long Zhang | First 5 Authors: Tinghui An, Tinghui An, , , | Summary: We report a mid-infrared ring laser via fiber-to-waveguide hybrid integration enabled by directional couplers fabricated in fluoride glasses. Directional couplers were inscribed into fluoride glass using femtosecond laser direct writing, forming low-loss waveguides with a high positive refractive index […]


Continue.. Optical Fiber-Waveguide Hybrid Architecture for Mid-Infrared Ring Lasers