Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Posted by dbos This Week: Neuroscience, UCSF

Kavli Affiliate: Robert Edwards | Authors: Rumi Habib, Ryan S. Roark, Hui Li, Andrew Jesse Connell, Michael P. Hogarty, Kshitij Wagh, Shuyi Wang, Lorie Marchitto, Ashwin N. Skelly, John W. Carey, Kirsten J. Sowers, Kasirajan Ayyanathan, Samantha J. Plante, Frederic Bibollet-Ruche, Younghoon Park, Colby J. Agostino, Ajay Singh, Christian L. Martella, Emily Lewis, Jinery Lora, […]


Continue.. Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Development of a Charge-Resistant Embedding Media for High-Performance Serial Block Face Imaging of Cells and Tissues

Posted by dbos This Week: Neuroscience, UCSD / Salk

Kavli Affiliate: Mark Ellisman | Authors: Thomas Deerinck, Steven Peltier and Mark Ellisman | Summary: Serial block-face scanning electron microscopy (SBEM) enables high-resolution 3D imaging of biological specimens but is often limited by specimen charging due to the use of non-conductive epoxy resins. While heavy metal staining and variable-pressure SEM can reduce charging, these methods […]


Continue.. Development of a Charge-Resistant Embedding Media for High-Performance Serial Block Face Imaging of Cells and Tissues

The shape of attention: How cognitive goals sculpt cortical representation of speech.

Posted by dbos Hopkins, This Week: Neuroscience

Kavli Affiliate: Mounya Elhilali | Authors: Moïra-Phoebé Huet and Mounya Elhilali | Summary: Perception requires more than passive sensing—it involves prioritizing the features most relevant to ongoing cognitive goals, a process guided by selective attention. A central question is whether attention operates by enhancing all features of a selected target, or by optimizing neural encoding […]


Continue.. The shape of attention: How cognitive goals sculpt cortical representation of speech.

AMOR: Adaptive Character Control through Multi-Objective Reinforcement Learning

Posted by dbos Cornell, This Week: Nanoscience

Kavli Affiliate: David Muller | First 5 Authors: Lucas N. Alegre, Agon Serifi, Ruben Grandia, David Müller, Espen Knoop | Summary: Reinforcement learning (RL) has significantly advanced the control of physics-based and robotic characters that track kinematic reference motion. However, methods typically rely on a weighted sum of conflicting reward functions, requiring extensive tuning to […]


Continue.. AMOR: Adaptive Character Control through Multi-Objective Reinforcement Learning

Measuring topological invariants of even-dimensional non-Hermitian systems through quench dynamics

Posted by dbos This Week: Theoretical Physics, UCAS

Kavli Affiliate: Long Zhang | First 5 Authors: Xiao-Dong Lin, Long Zhang, , , | Summary: The accurate determination of non-Hermitian (NH) topological invariants plays a central role in the study of NH topological phases. In this work, we propose a general framework for directly measuring NH topological invariants in even-dimensional systems through quench dynamics. […]


Continue.. Measuring topological invariants of even-dimensional non-Hermitian systems through quench dynamics

RoboTransfer: Geometry-Consistent Video Diffusion for Robotic Visual Policy Transfer

Posted by dbos This Week: Theoretical Physics, UCAS

Kavli Affiliate: Zheng Zhu | First 5 Authors: Liu Liu, Xiaofeng Wang, Guosheng Zhao, Keyu Li, Wenkang Qin | Summary: Imitation Learning has become a fundamental approach in robotic manipulation. However, collecting large-scale real-world robot demonstrations is prohibitively expensive. Simulators offer a cost-effective alternative, but the sim-to-real gap make it extremely challenging to scale. Therefore, […]


Continue.. RoboTransfer: Geometry-Consistent Video Diffusion for Robotic Visual Policy Transfer

Theory of chiral-phonon-activated spin Seebeck effect

Posted by dbos This Week: Theoretical Physics, UCAS

Kavli Affiliate: Mamoru Matsuo | First 5 Authors: Naoki Nishimura, Takumi Funato, Mamoru Matsuo, Takeo Kato, | Summary: We theoretically explore the generation of spin current driven by a temperature gradient in a junction between a chiral insulator and a normal metal. Based on the gyromagnetic effect caused by microscopic rotation due to phonons, we […]


Continue.. Theory of chiral-phonon-activated spin Seebeck effect