A feedforward mechanism for human-like contour integration

Kavli Affiliate: George A. Alvarez | Authors: Fenil R. Doshi, Talia Konkle and George A. Alvarez | Summary: Summary: Deep neural network models provide a powerful experimental platform for exploring core mechanisms underlying human visual perception, such as perceptual grouping and contour integration — the process of linking local edge elements to arrive at a […]


Continue.. A feedforward mechanism for human-like contour integration

Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo

Kavli Affiliate: Michael Miller | Authors: Juthi Biswas, Dilruba Akter, Michael J Miller, Dennis J Thiele, Eain A. Murphy, Christine O’Connor, Jennifer F Moffat and Gary Chan | Summary: Summary: FDA-approved antivirals against HCMV have several limitations, including only targeting the later stages of the viral replication cycle, adverse side effects, and the emergence of […]


Continue.. Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo

Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy

Kavli Affiliate: Alexandra Nelson | Authors: Rose B Creed, Scott C Harris, Sadhana Sridhar, Sascha du Lac, David S Zee, Felice A Dunn, Guy Bouvier and Alexandra B Nelson | Summary: Summary: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder with an estimated prevalence of 5-7 people in 100,000. Clinically characterized by impairments in gait, […]


Continue.. Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy

Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands

Kavli Affiliate: Joshua Berke and Loren Frank | Authors: Alison E. Comrie, Emily J. Monroe, Ari E. Kahn, Eric L. Denovellis, Abhilasha Joshi, Jennifer A. Guidera, Timothy A. Krausz, Joshua D. Berke, Nathaniel D. Daw and Loren M. Frank | Summary: Summary: The cognitive ability to go beyond the present to consider alternative possibilities, including […]


Continue.. Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands

Ensemble Kalman Filter Data Assimilation Into Surface Flux Transport Model To Infer Surface Flows: An Observing System Simulation Experiment

Kavli Affiliate: J. Todd Hoeksema | First 5 Authors: Soumyaranjan Dash, Marc L. DeRosa, Mausumi Dikpati, Xudong Sun, Sushant S. Mahajan | Summary: Knowledge of the global magnetic field distribution and its evolution on the Sun’s surface is crucial for modeling the coronal magnetic field, understanding solar wind dynamics, computing the heliospheric open flux distribution […]


Continue.. Ensemble Kalman Filter Data Assimilation Into Surface Flux Transport Model To Infer Surface Flows: An Observing System Simulation Experiment

Decoding the hidden dynamics of super-Arrhenius hydrogen diffusion in multi-principal element alloys via machine learning

Kavli Affiliate: Wei Gao | First 5 Authors: Fei Shuang, Yucheng Ji, Zixiong Wei, Chaofang Dong, Wei Gao | Summary: Understanding atomic hydrogen (H) diffusion in multi-principal element alloys (MPEAs) is essential for advancing clean energy technologies such as H transport, storage, and nuclear fusion applications. However, the vast compositional space and the intricate chemical […]


Continue.. Decoding the hidden dynamics of super-Arrhenius hydrogen diffusion in multi-principal element alloys via machine learning

High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes

Kavli Affiliate: Edward Callaway | Authors: Li Alex Zhang, Peichao Li and Edward M. Callaway | Summary: Summary: Laminar electrode arrays allow simultaneous recording of activity of many cortical neurons and assignment to layers using current source density (CSD) analyses. Electrode arrays with 100-micron contact spacing have been used to estimate borders between layer 4 […]


Continue.. High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes

The HIV-1 Nuclear Export Complex Reveals the Role of RNA in Crm1 Cargo Recognition

Kavli Affiliate: Keri Martinowich | Authors: Amber M Smith, Yang Li, Arianna Velarde, Yifan Cheng and Alan D. Frankel | Summary: Summary: Crm1 is a highly conserved nuclear exportin that transports >1000 human proteins including ribonucleoprotein (RNP) complexes. The interface between Crm1 and RNP cargos is unknown. The HIV regulatory protein, Rev, was one of […]


Continue.. The HIV-1 Nuclear Export Complex Reveals the Role of RNA in Crm1 Cargo Recognition

Transcriptomic characterization of human lateral septum neurons reveals conserved and divergent marker genes across species

Kavli Affiliate: Keri Martinowich | Authors: Robert A Phillips III, Seyun Oh, Svitlana V Bach, Yufeng Du, Ryan A Miller, Joel E Kleinman, Thomas M Hyde, Stephanie C Hicks, Stephanie Cerceo Page and Keri Martinowich | Summary: The lateral septum (LS) is a midline, subcortical structure, which regulates social behaviors that are frequently impaired in […]


Continue.. Transcriptomic characterization of human lateral septum neurons reveals conserved and divergent marker genes across species

Predicting User Stances from Target-Agnostic Information using Large Language Models

Kavli Affiliate: Wei Gao | First 5 Authors: Siyuan Brandon Loh, Liang Ze Wong, Prasanta Bhattacharya, Joseph Simons, Wei Gao | Summary: We investigate Large Language Models’ (LLMs) ability to predict a user’s stance on a target given a collection of his/her target-agnostic social media posts (i.e., user-level stance prediction). While we show early evidence […]


Continue.. Predicting User Stances from Target-Agnostic Information using Large Language Models