Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk

Posted by dbos Hopkins

Kavli Affiliate: Michael Miller | Authors: Hannah Mummey, Weston Elison, Katha Korgaonkar, Ruth Elgamel, Parul Kudtarkar, Emily Griffin, Paola Benaglio, Michael Miller, Alokkumar Jha, Jocelyn E Manning Fox, Mark Mccarthy, Sebastian Preissl, Anna L Gloyn, Patrick E Macdonald and Kyle J Gaulton | Summary: Physiological variability in pancreatic cell type gene regulation and the impact […]


Continue.. Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk

3D histology reveals that immune response to pancreatic precancers is heterogeneous and depends on global pancreas structure

Posted by dbos Hopkins

Kavli Affiliate: Denis Wirtz | Authors: Ashley L Kiemen, Cristina Almagro Perez, Valentina Matos Romero, André Forjaz, Alicia M Braxton, Lucie Dequiedt, Jeeun Parksong, Courtney D Cannon, Xuan Yuan, Sarah M Shin, Jaanvi Mahesh Babu, Elizabeth D Thompson, Toby C Cornish, Won Jin Ho, Laura D Wood, PeiHsun Wu, Arrate Munoz-Barrutia, Ralph H Hruban and […]


Continue.. 3D histology reveals that immune response to pancreatic precancers is heterogeneous and depends on global pancreas structure

A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding

Posted by dbos UCSF

Kavli Affiliate: Xin Duan | Authors: Travis D Goode, Jason Bondoc Alipio, Antoine Besnard, Devesh Pathak, Michael Kritzer-Cheren, Ain Chung, Xin Duan and Amar Sahay | Summary: Adaptive regulation of feeding depends on linkage of internal states and food outcomes with contextual cues. Human brain imaging has identified dysregulation of a hippocampal-lateral hypothalamic area (LHA) […]


Continue.. A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding

COOL-LAMPS VIII: Known wide-separation lensed quasars and their host galaxies reveal a lack of evolution in $M_{rm{BH}}/M_star$ since $zsim 3$

Posted by dbos Chicago

Kavli Affiliate: Michael D. Gladders | First 5 Authors: Aidan P. Cloonan, Gourav Khullar, Kate A. Napier, Michael D. Gladders, Håkon Dahle | Summary: Wide-separation lensed quasars (WSLQs) are a rare class of strongly lensed quasars, magnified by foreground massive galaxy clusters, with typically large magnifications of the multiple quasar images. They are a relatively […]


Continue.. COOL-LAMPS VIII: Known wide-separation lensed quasars and their host galaxies reveal a lack of evolution in $M_{rm{BH}}/M_star$ since $zsim 3$

Jet Definition and Transverse-Momentum-Dependent Factorization in Semi-Inclusive Deep-Inelastic Scattering

Posted by dbos Peking

Kavli Affiliate: Feng Yuan | First 5 Authors: Paul Caucal, Edmond Iancu, A. H. Mueller, Feng Yuan, | Summary: Using the colour dipole picture of Deep Inelastic Scattering (DIS) and the Colour Glass Condensate effective theory, we study semi-inclusive jet production in DIS at small $x$ in the limit where the photon virtuality $Q^2$ is […]


Continue.. Jet Definition and Transverse-Momentum-Dependent Factorization in Semi-Inclusive Deep-Inelastic Scattering

Long-range optomechanical interactions in SiN membrane arrays

Posted by dbos Delft

Kavli Affiliate: Simon Groblacher | First 5 Authors: Xiong Yao, Matthijs H. J. de Jong, Jie Li, Simon Gröblacher, | Summary: Optomechanical systems using a membrane-in-the-middle configuration can exhibit a long-range type of interaction similar to how atoms show collective motion in an optical potential. Photons bounce back and forth inside a high-finesse Fabry-P'{e}rot cavity […]


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Conservation, alteration, and redistribution of mammalian striatal interneurons

Posted by dbos UCSF

Kavli Affiliate: Alex Pollen | Authors: Emily K Corrigan, Michael DeBerardine, Aunoy Poddar, Miguel Turrero Garcia, Matthew T Schmitz, Corey Harwell, Mercedes Paredes, Fenna M Krienen and Alex Aaron Pollen | Summary: Mammalian brains vary in size, structure, and function, but the extent to which evolutionarily novel cell types contribute to this variation remains unresolved1–4. […]


Continue.. Conservation, alteration, and redistribution of mammalian striatal interneurons

A familial, telomere-to-telomere reference for human de novo mutation and recombination from a four-generation pedigree

Posted by dbos Columbia

Kavli Affiliate: Michael Goldberg | Authors: David Porubsky, Harriet Dashnow, Thomas A. Sasani, Glennis A. Logsdon, Pille Hallast, Michelle D. Noyes, Zev N. Kronenberg, Tom Mokveld, Nidhi Koundinya, Cillian Nolan, Cody J. Steely, Andrea Guarracino, Egor Dolzhenko, William T. Harvey, William J. Rowell, Kirill Grigorev, Thomas J. Nicholas, Keisuke K. Oshima, Jiadong Lin, Peter Ebert, […]


Continue.. A familial, telomere-to-telomere reference for human de novo mutation and recombination from a four-generation pedigree

JADES Ultra-red Flattened Objects: Morphologies and Spatial Gradients in Color and Stellar Populations

Posted by dbos Cambridge

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Justus L. Gibson, Erica Nelson, Christina C. Williams, Sedona H. Price, Katherine E. Whitaker | Summary: One of the more surprising findings after the first year of JWST observations is the large number of spatially extended galaxies (ultra-red flattened objects, or UFOs) among the optically-faint galaxy population […]


Continue.. JADES Ultra-red Flattened Objects: Morphologies and Spatial Gradients in Color and Stellar Populations