A spatial model of autophosphorylation of Ca2+/calmodulin-dependent protein kinase II (CaMKII) predicts that the lifetime of phospho-CaMKII after induction of synaptic plasticity is greatly prolonged by CaM-trapping.

Posted by dbos UCSD / Salk

Kavli Affiliate: Terrence Sejnowski | Authors: Thomas M Bartol, Mariam Ordyan, Terrence J Sejnowski, Padmini Rangamani and Mary B Kennedy | Summary: Long-term potentiation (LTP) is a biochemical process that underlies learning in excitatory glutamatergic synapses in the Central Nervous System (CNS). The critical early driver of LTP is autophosphorylation of the abundant postsynaptic enzyme, […]


Continue.. A spatial model of autophosphorylation of Ca2+/calmodulin-dependent protein kinase II (CaMKII) predicts that the lifetime of phospho-CaMKII after induction of synaptic plasticity is greatly prolonged by CaM-trapping.

Functional organization and natural scene responses across mouse visual cortical areas revealed with encoding manifolds – Copy

Posted by dbos Rockefeller

Kavli Affiliate: Roderick MacKinnon | Authors: Venkata Shiva Mandala and Roderick MacKinnon | Summary: Gating in voltage-dependent ion channels is regulated by the transmembrane voltage. This form of regulation is enabled by voltage sensing domains (VSDs) that respond to transmembrane voltage differences by changing their conformation and exerting force on the pore to open or […]


Continue.. Functional organization and natural scene responses across mouse visual cortical areas revealed with encoding manifolds – Copy

Functional organization and natural scene responses across mouse visual cortical areas revealed with encoding manifolds

Posted by dbos UCSF

Kavli Affiliate: Michael Stryker | Authors: Luciano Dyballa, Greg D Field, Michael P Stryker and Steven W Zucker | Summary: A challenge in sensory neuroscience is understanding how populations of neurons operate in concert to represent diverse stimuli. To meet this challenge, we have created “encoding manifolds” that reveal the overall responses of brain areas […]


Continue.. Functional organization and natural scene responses across mouse visual cortical areas revealed with encoding manifolds

Image Processing in the Acute to Chronic Pain Signatures (A2CPS) Project

Posted by dbos Hopkins

Kavli Affiliate: Brian Caffo | Authors: Patrick Sadil, Konstantinos Arfanakis, Enamul Hoque Bhuiyan, Brian Caffo, Vince D Calhoun, Daniel J Clauw, Mark C DeLano, James C Ford, Ramtalik Gattu, Xiaodong Guo, Richard E Harris, Eric Ichesco, Micah A Johnson, Heejung Jung, Ari B Kahn, Chelsea M Kaplan, Nondas Leloudas, Martin A Lindquist, Qingfei Luo, Todd […]


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A Versatile Chip-Scale Platform for High-Rate Entanglement Generation using an AlGaAs Microresonator Array

Posted by dbos UCSB

Kavli Affiliate: John E. Bowers | First 5 Authors: Yiming Pang, Joshua E. Castro, Trevor J. Steiner, Liao Duan, Noemi Tagliavacche | Summary: Integrated photonic microresonators have become an essential resource for generating photonic qubits for quantum information processing, entanglement distribution and networking, and quantum communications. The pair generation rate is enhanced by reducing the […]


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Focal Plane of the Arcus Probe X-Ray Spectrograph

Posted by dbos MIT

Kavli Affiliate: Marshall W. Bautz | First 5 Authors: Catherine E. Grant, Marshall W. Bautz, Eric D. Miller, Richard F. Foster, Beverly LaMarr | Summary: The Arcus Probe mission concept provides high-resolution soft X-ray and UV spectroscopy to reveal feedback-driven structure and evolution throughout the universe with an agile response capability ideal for probing the […]


Continue.. Focal Plane of the Arcus Probe X-Ray Spectrograph

Kramers-protected hardware-efficient error correction with Andreev spin qubits

Posted by dbos Delft

Kavli Affiliate: Anton R. Akhmerov | First 5 Authors: Haoran Lu, Isidora Araya Day, Anton R. Akhmerov, Bernard van Heck, Valla Fatemi | Summary: We propose an architecture for bit flip error correction of Andreev spins that is protected by Kramers’ degeneracy. Specifically, we show that a coupling network of linear inductors results in a […]


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Not all cross-modal responses are explained by face movements

Posted by dbos UCSF

Kavli Affiliate: Andrea Hasenstaub | Authors: Timothy R Olsen and Andrea R Hasenstaub | Summary: Recent work has claimed that most apparently cross-modal responses in sensory cortex are instead caused by the face movements evoked by stimuli of the non-dominant modality. We show that visual stimuli rarely trigger face movements in awake mice; when they […]


Continue.. Not all cross-modal responses are explained by face movements

A Brain-Wide Map of Neural Activity during Complex Behaviour

Posted by dbos Columbia

Kavli Affiliate: Liam Paninski | Authors: International Brain Lab, Brandon Benson, Julius Benson, Daniel Birman, Niccolo Bonacchi, Matteo Carandini, Joana A Catarino, Gaelle A Chapuis, Anne K Churchland, Yang Dan, Peter Dayan, Eric EJ DeWitt, Tatiana A Engel, Michele Fabbri, Mayo Faulkner, Ila Rani Fiete, Charles Findling, Laura Freitas-Silva, Berk Gercek, Kenneth D Harris, Michael […]


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A two-dimensional 10-qubit array in germanium with robust and localised qubit control

Posted by dbos Delft

Kavli Affiliate: Menno Veldhorst | First 5 Authors: Valentin John, Cécile X. Yu, Barnaby van Straaten, Esteban A. Rodríguez-Mena, Mauricio Rodríguez | Summary: Quantum computers require the systematic operation of qubits with high fidelity. For holes in germanium, the spin-orbit interaction allows for textit{in situ} electric fast and high-fidelity qubit gates. However, the interaction also […]


Continue.. A two-dimensional 10-qubit array in germanium with robust and localised qubit control