A spatial model of autophosphorylation of Ca2+/calmodulin-dependent protein kinase II in a glutamatergic spine reveals dynamics of kinase activation in the first several seconds after a complex synaptic stimulus.

Kavli Affiliate: Terrence Sejnowski | Authors: Thomas M Bartol, Mariam Ordyan, Terrence J Sejnowski, Padmini Rangamani and Mary B Kennedy | Summary: Long-term potentiation (LTP) is a biochemical process in excitatory glutamatergic synapses in the Central Nervous System (CNS). It is initiated by a bout of synaptic activation that is strong enough to contribute to […]


Continue.. A spatial model of autophosphorylation of Ca2+/calmodulin-dependent protein kinase II in a glutamatergic spine reveals dynamics of kinase activation in the first several seconds after a complex synaptic stimulus.

The Neurobiology of Cognitive Fatigue and Its Influence on Effort-Based Choice

Kavli Affiliate: Vikram Chib | Authors: Grace E Steward and Vikram S Chib | Summary: Feelings of cognitive fatigue emerge through repeated mental exertion and are ubiquitous in our daily lives. However, there is a limited understanding of the neurobiological mechanisms underlying the influence of cognitive fatigue on decisions to exert. We use functional magnetic […]


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Resistance to age-related hearing loss in the echolocating big brown bat (Eptesicus fuscus)

Kavli Affiliate: Denis Wirtz | Authors: Wenxuan Du, Bryan Zhou, André Forjaz, Sarah M. Shin, Fan Wu, Ashleigh J. Crawford, Praful R. Nair, Adrian C. Johnston, Hoku West-Foyle, Ashley Tang, Dongjoo Kim, Rong Fan, Ashley L. Kiemen, Pei-Hsun Wu, Jude M. Phillip, Won Jin Ho, David E. Sanin and Denis Wirtz | Summary: Enrichment of […]


Continue.. Resistance to age-related hearing loss in the echolocating big brown bat (Eptesicus fuscus)

High-motility pro-tumorigenic monocytes drive macrophage enrichment in the tumor microenvironment

Kavli Affiliate: Denis Wirtz | Authors: Wenxuan Du, Bryan Zhou, André Forjaz, Sarah M. Shin, Fan Wu, Ashleigh J. Crawford, Praful R. Nair, Adrian C. Johnston, Hoku West-Foyle, Ashley Tang, Dongjoo Kim, Rong Fan, Ashley L. Kiemen, Pei-Hsun Wu, Jude M. Phillip, Won Jin Ho, David E. Sanin and Denis Wirtz | Summary: Enrichment of […]


Continue.. High-motility pro-tumorigenic monocytes drive macrophage enrichment in the tumor microenvironment

Sst- and Vip-Cre mouse lines without age-related hearing loss

Kavli Affiliate: Andrea Hasenstaub | Authors: Calvin T Foss, Timothy Olsen, James Bigelow and Andrea R Hasenstaub | Summary: GABAergic interneurons, including somatostatin (SST) and vasoactive intestinal peptide (VIP) positive cells, play a crucial role in cortical circuit processing. Cre recombinase-mediated manipulation of these interneurons is facilitated by commercially available knock-in mouse strains such as […]


Continue.. Sst- and Vip-Cre mouse lines without age-related hearing loss

Analysis of the full Spitzer microlensing sample I: Dark remnant candidates and Gaia predictions

Kavli Affiliate: Michael M. Fausnaugh | First 5 Authors: Krzysztof A. Rybicki, Yossi Shvartzvald, Jennifer C. Yee, Sebastiano Calchi Novati, Eran O. Ofek | Summary: In the pursuit of understanding the population of stellar remnants within the Milky Way, we analyze the sample of $sim 950$ microlensing events observed by the Spitzer Space Telescope between […]


Continue.. Analysis of the full Spitzer microlensing sample I: Dark remnant candidates and Gaia predictions

All-optical Loss-tolerant Distributed Quantum Sensing

Kavli Affiliate: Alireza Marandi | First 5 Authors: Rajveer Nehra, Changhun Oh, Liang Jiang, Alireza Marandi, | Summary: Distributed quantum sensing (DQS) leverages quantum resources to estimate an unknown global property of a networked quantum sensor beyond the classical limit. We propose and analyze an all-optical resource-efficient scheme for the next-generation DQS systems. Our method […]


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Research on Tibetan Tourism Viewpoints information generation system based on LLM

Kavli Affiliate: Ke Wang | First 5 Authors: Jinhu Qi, Shuai Yan, Wentao Zhang, Yibo Zhang, Zirui Liu | Summary: Tibet, ensconced within China’s territorial expanse, is distinguished by its labyrinthine and heterogeneous topography, a testament to its profound historical heritage, and the cradle of a unique religious ethos. The very essence of these attributes, […]


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0.7 MW Yb:YAG pumped degenerate optical parametric oscillator at 2.06 μm

Kavli Affiliate: Alireza Marandi | First 5 Authors: Anni Li, Mehran Bahri, Robert M. Gray, Seowon Choi, Sajjad Hoseinkhani | Summary: Frequency comb and field-resolved broadband absorption spectroscopy are promising techniques for rapid, precise, and sensitive detection of short-lived atmospheric pollutants on-site. Enhancing detection sensitivity in absorption spectroscopy hinges on bright sources that cover molecular […]


Continue.. 0.7 MW Yb:YAG pumped degenerate optical parametric oscillator at 2.06 μm

Approach for composition measurement of cosmic rays using the muon-to-electron ratio observed by LHAASO-KM2A

Kavli Affiliate: Zhuo Li | First 5 Authors: Xishui Tian, Zhuo Li, Quanbu Gou, Hengying Zhang, Huihai He | Summary: Composition measurement of cosmic rays (CRs) around the knee of the CR energy spectrum is crucial for studying the processes of particle acceleration and propagation of Galactic CRs. The Square Kilometer Array (KM2A) of Large […]


Continue.. Approach for composition measurement of cosmic rays using the muon-to-electron ratio observed by LHAASO-KM2A