Supervised Learning and Large Language Model Benchmarks on Mental Health Datasets: Cognitive Distortions and Suicidal Risks in Chinese Social Media

Kavli Affiliate: Dan Luo | First 5 Authors: Hongzhi Qi, Qing Zhao, Jianqiang Li, Changwei Song, Wei Zhai | Summary: On social media, users often express their personal feelings, which may exhibit cognitive distortions or even suicidal tendencies on certain specific topics. Early recognition of these signs is critical for effective psychological intervention. In this […]


Continue.. Supervised Learning and Large Language Model Benchmarks on Mental Health Datasets: Cognitive Distortions and Suicidal Risks in Chinese Social Media

Supervised Learning and Large Language Model Benchmarks on Mental Health Datasets: Cognitive Distortions and Suicidal Risks in Chinese Social Media

Kavli Affiliate: Dan Luo | First 5 Authors: Hongzhi Qi, Qing Zhao, Changwei Song, Wei Zhai, Dan Luo | Summary: In the realm of social media, users frequently convey personal sentiments, with some potentially indicating cognitive distortions or suicidal tendencies. Timely recognition of such signs is pivotal for effective interventions. In response, we introduce two […]


Continue.. Supervised Learning and Large Language Model Benchmarks on Mental Health Datasets: Cognitive Distortions and Suicidal Risks in Chinese Social Media

Evaluating the Efficacy of Supervised Learning vs Large Language Models for Identifying Cognitive Distortions and Suicidal Risks in Chinese Social Media

Kavli Affiliate: Dan Luo | First 5 Authors: Hongzhi Qi, Qing Zhao, Changwei Song, Wei Zhai, Dan Luo | Summary: Large language models, particularly those akin to the rapidly progressing GPT series, are gaining traction for their expansive influence. While there is keen interest in their applicability within medical domains such as psychology, tangible explorations […]


Continue.. Evaluating the Efficacy of Supervised Learning vs Large Language Models for Identifying Cognitive Distortions and Suicidal Risks in Chinese Social Media

Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need

Kavli Affiliate: Alipasha Vaziri, Jeffrey M. Friedman | Authors: Bowen Tan, Caleb J Browne, Tobias Nobauer, Alipasha Vaziri, Jeffrey M. Friedman and Eric J. Nestler | Summary: Addiction prioritizes drug use over innate needs by hijacking brain circuits that direct motivation, but how this develops remains unclear. Using whole-brain FOS mapping and in vivo single-neuron […]


Continue.. Drugs of abuse hijack a mesolimbic pathway that processes homeostatic need

Virion-associated US28 rapidly modulates Akt activity to suppress HCMV lytic replication in monocytes

Kavli Affiliate: Michael Miller | Authors: Jamil Mahmud, Brittany W Geiler, Juthi Biswas, Michael J Miller, Julia E Myers, Stephen M Matthews, Amanda B Wass, Christine M O’Connor and Gary C Chan | Summary: Establishing a non-productive quiescent/silent infection within monocytes is essential for spread of human cytomegalovirus (HCMV). Yet, how HCMV establishes a quiescent […]


Continue.. Virion-associated US28 rapidly modulates Akt activity to suppress HCMV lytic replication in monocytes

Reward expectation selectively boosts the firing of accumbens D1+ neurons during motivated approach

Kavli Affiliate: Joshua Berke | Authors: Thomas Faust, Ali Mohebi and Joshua D Berke | Summary: The nucleus accumbens (NAc) helps govern motivation to pursue rewards. Two distinct sets of NAc projection neurons – expressing dopamine D1 versus D2 receptors – are thought to promote and suppress motivated behaviors respectively. However, support for this conceptual […]


Continue.. Reward expectation selectively boosts the firing of accumbens D1+ neurons during motivated approach

The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

Kavli Affiliate: Keri Martinowich | Authors: Lukas M Weber, Heena R Divecha, Matthew N Tran, Sang Ho Kwon, Abby Spangler, Kelsey D Montgomery, Madhavi Tippani, Rahul Bharadwaj, Joel E Kleinman, Stephanie C Page, Thomas M Hyde, Leonardo Collado-Torres, Kristen R Maynard, Keri Martinowich and Stephanie C Hicks | Summary: Norepinephrine (NE) neurons in the locus […]


Continue.. The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

Costs of resistance limit the effectiveness of cooperation enforcement

Kavli Affiliate: Michael Miller | Authors: Michael E Miller, Susan Sidell and Elizabeth A Ostrowski | Summary: Cooperative groups are susceptible to invasion by cheaters that reap the benefits but fail to pay the costs. Both theory and experimental work have shown that cheating can select for counter-adaptations to resist cheating. But then why is […]


Continue.. Costs of resistance limit the effectiveness of cooperation enforcement

PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression

Kavli Affiliate: Bjoern Schwer | Authors: Christin Schmidt, Sarah Cohen, Brian L. Gudenas, Sarah Husain, Annika Carlson, Samantha Westelman, Linyu Wang, Joanna J. Phillips, Paul A. Northcott, William A. Weiss and Bjoern Schwer | Summary: SNCAIP duplication may promote Group 4 medulloblastoma via induction of PRDM6, a poorly characterized member of the PRDF1 and RIZ1 […]


Continue.. PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression

Laws for Glia Organization Conserved Across Mammals

Kavli Affiliate: Terrence Sejnowski | Authors: Antonio Pinto-Duarte, Katharine Bogue, Terrence J. Sejnowski and Shyam Srinivasan | Summary: The organizational principles of glia remain largely unknown despite their vital role in nervous system function. Previous work has shown that the number of glia per unit volume of neocortex is constant across mammalian species. We hypothesize […]


Continue.. Laws for Glia Organization Conserved Across Mammals