Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models

Kavli Affiliate: Richard Huganir | Authors: Sureni H. Sumathipala, Suha Khan, Robert A. Kozol, Yoichi Araki, Sheyum Syed, Richard L. Huganir and Julia Dallman | Summary: Background and Aims SYNGAP1 disorder is a prevalent genetic form of Autism Spectrum Disorder and Intellectual Disability (ASD/ID) and is caused by de novo or inherited mutations in one […]


Continue.. Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models

Loss of cilia after neurulation impacts brain development and neuronal activity in larval zebrafish

Kavli Affiliate: Emre Yaksi | Authors: Percival P D’Gama, Inyoung Jeong, Andreas M Nygaard, Anh-Tuan Trinh, Emre Yaksi and Nathalie Jurisch-Yaksi | Summary: Cilia are slender, hair-like structures extending from cell surfaces and playing essential roles in diverse physiological processes. Within the nervous system, primary cilia contribute to signaling and sensory perception, while motile cilia […]


Continue.. Loss of cilia after neurulation impacts brain development and neuronal activity in larval zebrafish

Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets

Kavli Affiliate: Rui Costa | Authors: Leslie J Sibener, Alice C Mosberger, Tiffany X Chen, Vivek R Athalye, James M Murray and Rui M Costa | Summary: Reaches are complex movements that are critical for survival, and encompass the control of different aspects such as direction, speed, and endpoint precision. Complex movements have been postulated […]


Continue.. Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets

Serotonin predictively encodes value

Kavli Affiliate: Jeremiah Cohen | Authors: Emerson F Harkin, Cooper D Grossman, Jeremiah Y Cohen, Jean-Claude Béïque and Richard Naud | Summary: The in vivo responses of dorsal raphe nucleus (DRN) serotonin neurons to emotionally-salient stimuli are a puzzle. Existing theories centred on reward, surprise, or uncertainty individually account for some aspects of serotonergic activity […]


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A Close Look at Ly$α$ Emitters with JWST/NIRCam at $zapprox3.1$

Kavli Affiliate: Linhua Jiang | First 5 Authors: Yixiao Liu, Y. Sophia Dai, Stijn Wuyts, Jia-Sheng Huang, Linhua Jiang | Summary: We study 10 spectroscopically confirmed Ly$alpha$ emitters (LAEs) at $zapprox3.1$ in the UDS field, covered by JWST/NIRCam in the PRIMER program. All LAEs are detected in all NIRCam bands from F090W to F444W, corresponding […]


Continue.. A Close Look at Ly$α$ Emitters with JWST/NIRCam at $zapprox3.1$

A Close Look at Ly$α$ Emitters with JWST/NIRCam at $zapprox3.1$

Kavli Affiliate: Linhua Jiang | First 5 Authors: Yixiao Liu, Y. Sophia Dai, Stijn Wuyts, Jia-Sheng Huang, Linhua Jiang | Summary: We study 10 spectroscopically confirmed Ly$alpha$ emitters (LAEs) at $zapprox3.1$ in the UDS field, covered by JWST/NIRCam in the PRIMER program. All LAEs are detected in all NIRCam bands from F090W to F444W, corresponding […]


Continue.. A Close Look at Ly$α$ Emitters with JWST/NIRCam at $zapprox3.1$

Reducing hardware requirements for entanglement distribution via joint hardware-protocol optimization

Kavli Affiliate: Stephanie Wehner | First 5 Authors: Adrià Labay-Mora, Francisco Ferreira da Silva, Stephanie Wehner, , | Summary: We conduct a numerical investigation of fiber-based entanglement distribution over distances of up to 1600km using a chain of processing-node quantum repeaters. We determine minimal hardware requirements while simultaneously optimizing over protocols for entanglement generation and […]


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Axion Curvaton Model for the Gravitational Waves Observed by Pulsar Timing Arrays

Kavli Affiliate: Masahiro Kawasaki | First 5 Authors: Keisuke Inomata, Masahiro Kawasaki, Kyohei Mukaida, Tsutomu T. Yanagida, | Summary: The stochastic gravitational wave background (SGWB) recently detected by the PTA collaborations could be the gravitational waves (GWs) induced by curvature perturbations. However, primordial black holes (PBHs) might be overproduced if the SGWB is explained by […]


Continue.. Axion Curvaton Model for the Gravitational Waves Observed by Pulsar Timing Arrays

Axion Curvaton Model for the Gravitational Waves Observed by Pulsar Timing Arrays

Kavli Affiliate: Masahiro Kawasaki | First 5 Authors: Keisuke Inomata, Masahiro Kawasaki, Kyohei Mukaida, Tsutomu T. Yanagida, | Summary: The stochastic gravitational wave background (SGWB) recently detected by the PTA collaborations could be the gravitational waves (GWs) induced by curvature perturbations. However, primordial black holes (PBHs) might be overproduced if the SGWB is explained by […]


Continue.. Axion Curvaton Model for the Gravitational Waves Observed by Pulsar Timing Arrays

Structural basis of TRPV1 modulation by endogenous bioactive lipids

Kavli Affiliate: Yifan Cheng | Authors: William Randall Arnold, Adamo S Mancino, Frank R Moss III, Adam Frost, David Julius and Yifan Cheng | Summary: TRP ion channels are modulated by phosphoinositide lipids, but the underlying structural mechanisms remain unclear. The capsaicin- and heat-activated receptor, TRPV1, has served as a model for deciphering lipid modulation, […]


Continue.. Structural basis of TRPV1 modulation by endogenous bioactive lipids