Optimality in superselective surface binding by multivalent DNA nanostars

Posted by klaurent Delft

Kavli Affiliate: Jos Zwanikken | Summary:Weak multivalent interactions govern a large variety of biological processes like cell-cell adhesion and virus-host interactions. These systems distinguish sharply between surfaces based on receptor density, known as superselectivity. Earlier experimental and theoretical work provided insights into the control of selectivity: Weak interactions and a high number of ligands facilitate […]


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SWAT: A System-Wide Approach to Tunable Leakage Mitigation in Encrypted Data Stores

Posted by dbos Peking

Kavli Affiliate: Hu Zhan | First 5 Authors: Leqian Zheng, Lei Xu, Cong Wang, Sheng Wang, Yuke Hu | Summary: Numerous studies have underscored the significant privacy risks associated with various leakage patterns in encrypted data stores. While many solutions have been proposed to mitigate these leakages, they either (1) incur substantial overheads, (2) focus […]


Continue.. SWAT: A System-Wide Approach to Tunable Leakage Mitigation in Encrypted Data Stores

SWAT: A System-Wide Approach to Tunable Leakage Mitigation in Encrypted Data Stores

Posted by dbos Peking

Kavli Affiliate: Hu Zhan | First 5 Authors: Leqian Zheng, Lei Xu, Cong Wang, Sheng Wang, Yuke Hu | Summary: Numerous studies have underscored the significant privacy risks associated with various leakage patterns in encrypted data stores. Most existing systems that conceal leakage either (1) incur substantial overheads, (2) focus on specific subsets of leakage […]


Continue.. SWAT: A System-Wide Approach to Tunable Leakage Mitigation in Encrypted Data Stores

Combinatorial transcription factor binding encodes cis-regulatory wiring of forebrain GABAergic neurogenesis

Posted by klaurent UCSF

Kavli Affiliate: John Rubenstein | Authors: Rinaldo Catta-Preta, Susan Lindtner, Athena Ypsilanti, James Price, Armen Abnousi, Linda Su-Feher, Yurong Wang, Ivan Juric, Ian Jones, Jennifer Akiyama, Ming Hu, Yin Shen, Axel Visel, Len Pennacchio, Diane Dickel, John Rubenstein and Alex Nord | Summary: Transcription factors (TFs) bind combinatorially to genomic cis-regulatory elements (cREs), orchestrating transcription […]


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Divergence Based Quadrangle and Applications

Posted by klaurent UCAS

Kavli Affiliate: Cheng Peng | First 5 Authors: Anton Malandii, Siddhartha Gupte, Cheng Peng, Stan Uryasev, | Summary: This paper introduces a novel framework for assessing risk and decision-making in the presence of uncertainty, the emph{$varphi$-Divergence Quadrangle}. This approach expands upon the traditional Risk Quadrangle, a model that quantifies uncertainty through four key components: emph{risk, […]


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Divergence Based Quadrangle and Applications

Posted by klaurent UCAS

Kavli Affiliate: Cheng Peng | First 5 Authors: Anton Malandii, Siddhartha Gupte, Cheng Peng, Stan Uryasev, | Summary: This paper introduces a novel framework for assessing risk and decision-making in the presence of uncertainty, the emph{$varphi$-Divergence Quadrangle}. This approach expands upon the traditional Risk Quadrangle, a model that quantifies uncertainty through four key components: emph{risk, […]


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Diffuse neutrino background from past core-collapse supernovae

Posted by klaurent Tokyo

Kavli Affiliate: Shunsaku Horiuchi | First 5 Authors: Shin’ichiro Ando, Nick Ekanger, Shunsaku Horiuchi, Yusuke Koshio, | Summary: Core-collapse supernovae are among the most powerful explosions in the universe, emitting thermal neutrinos that carry away the majority of the gravitational binding energy released. These neutrinos create a diffuse supernova neutrino background (DSNB), one of the […]


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The evolution and mutational robustness of chromatin accessibility in Drosophila

Posted by klaurent Rockefeller

Kavli Affiliate: Li Zhao | Authors: Samuel Khodursky, Eric B Zheng, Nicolas Svetec, Sylvia M Durkin, Sigi Benjamin, Alice Gadau, Xia Wu and Li Zhao | Summary: The evolution of regulatory regions in the genome plays a critical role in shaping the diversity of life. While this process is primarily sequence-dependent, the enormous complexity of […]


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Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling

Posted by klaurent NTNU

Kavli Affiliate: Menno Witter | Authors: Katrine Sjaastad Hanssen, Nicolai Winter-Hjelm, Salome Nora Niethammer, Asgeir Kobro-Flatmoen, Menno P. Witter, Axel Sandvig and Ioanna Sandvig | Summary: Engineered biological neural networks are indispensable tools for investigating neural function in both healthy and diseased states from the subcellular to the network level. Neurons in vitro self-organize over […]


Continue.. Reverse Engineering of Feedforward Cortical-Hippocampal Neural Networks Relevant for Preclinical Disease Modelling