Report of the Instrumentation Frontier Working Group for Snowmass 2021

Kavli Affiliate: Kent Irwin | First 5 Authors: Phil Barbeau, Petra Merkel, Jinlong Zhang, Darin Acosta, Anthony A. Affolder | Summary: Detector instrumentation is at the heart of scientific discoveries. Cutting edge technologies enable US particle physics to play a leading role worldwide. This report summarizes the current status of instrumentation for High Energy Physics […]


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On ${mathcal N}=4$ supersymmetry enhancements in three dimensions

Kavli Affiliate: Yuji Tachikawa | First 5 Authors: Benjamin Assel, Yuji Tachikawa, Alessandro Tomasiello, , | Summary: We introduce a class of 3d theories consisting of strongly-coupled ${mathcal N}=4$ systems coupled to ${mathcal N}=3$ Chern-Simons gauge multiplets, which exhibit ${mathcal N}=4$ enhancements when a peculiar condition on the Chern-Simons levels is met. An example is […]


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Zero-Shot 3D Drug Design by Sketching and Generating

Kavli Affiliate: Yi Zhou | First 5 Authors: Siyu Long, Yi Zhou, Xinyu Dai, Hao Zhou, | Summary: Drug design is a crucial step in the drug discovery cycle. Recently, various deep learning-based methods design drugs by generating novel molecules from scratch, avoiding traversing large-scale drug libraries. However, they depend on scarce experimental data or […]


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Feasibility Analyses and Experimental Confirmation of Dove Prism Based Dual-fiberscope Rotary Joint

Kavli Affiliate: Xingde Li | Authors: Yuehan Liu, Hyeon-Cheol Park, Haolin Zhang and Xingde Li | Summary: Abstract Two-photon fluorescence microscopy has enjoyed its wide adoption in neuroscience. Head-mounted miniaturized fiberscopes offered an exciting opportunity for enabling neural imaging in freely-behaving animals with high 3D resolution. Here we propose a dual-fiberscope rotary joint based on […]


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Validation of TOI-1221 b, a warm sub-Neptune exhibiting TTVs around a Sun-like star

Kavli Affiliate: Roland Vanderspek | First 5 Authors: Christopher R. Mann, David Lafrenière, Diana Dragomir, Samuel N. Quinn, Thiam-Guan Tan | Summary: We present a successful validation of the long-period ($91.68278^{+0.00032}_{-0.00041}$ days) transiting sub-Neptune planet TOI-1221 b (TIC 349095149.01) around a Sun-like (m$_{rm V}$=10.5) star. We combine {it TESS} light curve measurements and ground-based time-series […]


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Mitf is a Schwann Cell Sensor of Axonal Integrity that Drives Nerve Repair

Kavli Affiliate: Samuel Pfaff | Authors: Lydia Daboussi, Giancarlo Costaguta, Miriam Gullo, Veronica Pessino, Brendan O’Leary, Karen Lettieri, Shawn Driscoll and Samuel L. Pfaff | Summary: Abstract Schwann cells respond to acute axon damage by transiently transdifferentiating into specialized repair cells that restore sensorimotor function. However, the molecular systems controlling repair cell formation and function […]


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Report of the Topical Group on Physics Beyond the Standard Model at Energy Frontier for Snowmass 2021

Kavli Affiliate: Marcela Carena | First 5 Authors: Tulika Bose, Antonio Boveia, Caterina Doglioni, Simone Pagan Griso, James Hirschauer | Summary: This is the Snowmass2021 Energy Frontier (EF) Beyond the Standard Model (BSM) report. It combines the EF topical group reports of EF08 (Model-specific explorations), EF09 (More general explorations), and EF10 (Dark Matter at Colliders). […]


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Role of the Hubble Scale in the Weak Lensing vs. CMB Tension

Kavli Affiliate: Wayne Hu | First 5 Authors: Lucas F. Secco, Tanvi Karwal, Wayne Hu, Elisabeth Krause, | Summary: We explore a re-parameterization of the lensing amplitude tension between weak lensing (WL) and cosmic microwave background (CMB) data and its implications for a joint resolution with the Hubble tension. Specifically, we focus on the lensing […]


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The Role of the Hubble Scale in the Weak Lensing vs. CMB Tension

Kavli Affiliate: Wayne Hu | First 5 Authors: Lucas F. Secco, Tanvi Karwal, Wayne Hu, Elisabeth Krause, | Summary: We explore a re-parameterization of the lensing amplitude tension between weak lensing (WL) and cosmic microwave background (CMB) data and its implications for a joint resolution with the Hubble tension. Specifically, we focus on the lensing […]


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A New Method for Finding Nearby White Dwarf Exoplanets and Detecting Biosignatures

Kavli Affiliate: Andrew Vanderburg | First 5 Authors: Mary Anne Limbach, Andrew Vanderburg, Kevin B. Stevenson, Simon Blouin, Caroline Morley | Summary: We demonstrate that the James Webb Space Telescope (JWST) can detect infrared (IR) excess from the blended light spectral energy distribution of spatially unresolved terrestrial exoplanets orbiting nearby white dwarfs. We find that […]


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