Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death during Mammary Gland Involution

Kavli Affiliate: Shawn Ferguson | Authors: Jaekwang Jeong, Jongwon Lee, Gabriel Talaia, Wonnam Kim, Junho Song, Kwangmin Yoo, David G. Gonzalez, Diana Athonvarangkul, Jaehun Shin, Pamela Dann, Ann M Haberman, Lark Kyun Kim, Shawn M. Ferguson, Jungmin Choi and John Wysolmerski | Summary: Involution of the mammary gland after lactation is a dramatic example of […]


Continue.. Intracellular Calcium links Milk Stasis to Lysosome Dependent Cell Death during Mammary Gland Involution

Serine Racemase is a Cysteine Racemase and Physiologic Down Regulator of Insulin Promoter Methylation

Kavli Affiliate: Solomon Snyder | Authors: Robin Roychaudhuri, Moataz M Gadalla, Lauren Albacarys, Timothy West, Harry Saavedra, Leon Mario Amzel and Solomon H. Snyder | Summary: Endogenous D-stereoisomers are being recognized as functionally important molecules in mammals. Here we report the first identification of endogenous D-cysteine in mammalian pancreas. Serine Racemase (SR) is the biosynthetic […]


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Clonally selected lines after CRISPR/Cas editing are not isogenic

Kavli Affiliate: Robert Edwards | Authors: Michael J. Roach, Sarah Beecroft, Kathie Mihindukulasuriya, Leran Wang, Lais Farias Oliveira Lima, Elizabeth A. Dinsdale, Robert Edwards and Scott Allyn Handley | Summary: The CRISPR-Cas9 system has enabled researchers to precisely modify/edit the sequence of a genome. A typical editing experiment consists of two steps: (i) editing cultured […]


Continue.. Clonally selected lines after CRISPR/Cas editing are not isogenic

Linear Sigma Dark Matter

Kavli Affiliate: Hitoshi Murayama | First 5 Authors: Dan Kondo, Robert McGehee, Tom Melia, Hitoshi Murayama, | Summary: We present a model of self-interacting dark matter based on QCD-like theories and inspired by the proximity of $a_0(980pm 20)$ to the $Kbar{K}(990)$ threshold. Dark matter is comprised of dark pions which self-scatter via the $sigma$ resonance […]


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Semi-inclusive Diffractive Deep Inelastic Scattering at Small-$x$

Kavli Affiliate: Feng Yuan | First 5 Authors: Yoshitaka Hatta, Bo-Wen Xiao, Feng Yuan, , | Summary: Inspired by a recent study of Iancu, Mueller and Triantafyllopoulos [1] and earlier papers by Golec-Biernat and Wusthoff [2,3], we propose semi-inclusive diffractive deep inelastic scattering (SIDDIS) to investigate the gluon tomography in the nucleon and nuclei at […]


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Hecatomb: An End-to-End Research Platform for Viral Metagenomics

Kavli Affiliate: Robert Edwards | Authors: Michael J. Roach, Sarah Beecroft, Kathie Mihindukulasuriya, Leran Wang, Lais Farias Oliveira Lima, Elizabeth A. Dinsdale, Robert Edwards and Scott Allyn Handley | Summary: Analysis of viral diversity using modern nucleic acid sequencing technologies presents several unique challenges. Foremost being that virus detection requires a non-targeted, random (shotgun) approach. […]


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Discrete time crystals enforced by Floquet-Bloch scars

Kavli Affiliate: Biao Huang | First 5 Authors: Biao Huang, Tsz-Him Leung, Dan Stamper-Kurn, W. Vincent Liu, | Summary: We analytically identify a new class of quantum scars protected by spatiotemporal translation symmetries, dubbed Floquet-Bloch scars. They distinguish from previous (quasi-)static scars by a rigid spectral pairing only possible in Floquet systems, where strong interaction […]


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Non-Universal Stellar Initial Mass Functions: Large Uncertainties in Star Formation Rates at $zapprox 2-4$ and Other Astrophysical Probes

Kavli Affiliate: Shunsaku Horiuchi | First 5 Authors: Joshua J. Ziegler, Thomas D. P. Edwards, Anna M. Suliga, Irene Tamborra, Shunsaku Horiuchi | Summary: We explore the assumption, widely used in many astrophysical calculations, that the stellar initial mass function (IMF) is universal across all galaxies. By considering both a canonical Salpeter-like IMF and a […]


Continue.. Non-Universal Stellar Initial Mass Functions: Large Uncertainties in Star Formation Rates at $zapprox 2-4$ and Other Astrophysical Probes

The Visual Survey Group: A Decade of Hunting Exoplanets and Unusual Stellar Events with Space-Based Telescopes

Kavli Affiliate: Andrew M. Vanderburg | First 5 Authors: Martti H. K. Kristiansen, Saul A. Rappaport, Andrew M. Vanderburg, Thomas L. Jacobs, Hans Martin Schwengeler | Summary: This article presents the history of the Visual Survey Group (VSG) – a Professional-Amateur (Pro-Am) collaboration within the field of astronomy working on data from several space missions […]


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The Visual Survey Group: A Decade of Hunting Exoplanets and Unusual Stellar Events with Space-Based Telescopes

Kavli Affiliate: Saul A. Rappaport | First 5 Authors: Martti H. K. Kristiansen, Saul A. Rappaport, Andrew M. Vanderburg, Thomas L. Jacobs, Hans Martin Schwengeler | Summary: This article presents the history of the Visual Survey Group (VSG) – a Professional-Amateur (Pro-Am) collaboration within the field of astronomy working on data from several space missions […]


Continue.. The Visual Survey Group: A Decade of Hunting Exoplanets and Unusual Stellar Events with Space-Based Telescopes