Nested sampling for physical scientists

Kavli Affiliate: Anthony Lasenby | First 5 Authors: Greg Ashton, Noam Bernstein, Johannes Buchner, Xi Chen, Gábor Csányi | Summary: We review Skilling’s nested sampling (NS) algorithm for Bayesian inference and more broadly multi-dimensional integration. After recapitulating the principles of NS, we survey developments in implementing efficient NS algorithms in practice in high-dimensions, including methods […]


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Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents

Kavli Affiliate: Menno Witter | Authors: Shinya Ohara, Märt Rannap, Ken-Ichiro Tsutsui, Andreas Draguhn, Alexei V. Egorov and Menno P. Witter | Summary: The general understanding of hippocampal circuits is that the hippocampus and the entorhinal cortex (EC) are topographically connected through parallel identical circuits along the dorsoventral axis. Our anterograde tracing and in vitro […]


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Machine-learning dissection of Human Accelerated Regions in primate neurodevelopment

Kavli Affiliate: Arnold Kriegstein, Alex Pollen | Authors: Sean Whalen, Fumitaka Inoue, Hane Ryu, Tyler Fair, Eirene Markenscoff-Papadimitriou, Kathleen Keough, Martin Kircher, Beth Martin, Beatriz Alvarado, Orry Elor, Dianne Laboy Cintron, Alex Williams, Md. Abul Hassan Samee, Sean Thomas, Robert Krencik, Erik Ullian, Arnold Kriegstein, Jay Shendure, Alex Pollen, Nadav Ahituv and Katherine Pollard | […]


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Collective effects in an incompressible electronic liquid

Kavli Affiliate: Yi Zhou | First 5 Authors: Jian-Jian Miao, Hui-Ke Jin, Yi Zhou, , | Summary: Starting from the Landau’s kinetic equation, we show that an electronic liquid in $d=2,3$ dimensions depicted by a Landau type effective theory will become incompressible on condition that the Landau parameters satisfy either (i) $1+F_{1}^{s}/d=0$ or (ii) $F_{0}^{s}to{}+infty$. […]


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MUSSES2020J: The Earliest Discovery of a Fast Blue Ultraluminous Transient at Redshift 1.063

Kavli Affiliate: Naoki Yasuda | First 5 Authors: Ji-an Jiang, Naoki Yasuda, Keiichi Maeda, Nozomu Tominaga, Mamoru Doi | Summary: In this Letter, we report the discovery of an ultraluminous fast-evolving transient in rest-frame UV wavelengths, MUSSES2020J, soon after its occurrence by using the Hyper Suprime-Cam (HSC) mounted on the 8.2 m Subaru telescope. The […]


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MUSSES2020J: The Earliest Discovery of a Fast Blue Ultra-luminous Transient at Redshift 1.063

Kavli Affiliate: Naoki Yasuda | First 5 Authors: Ji-an Jiang, Naoki Yasuda, Keiichi Maeda, Nozomu Tominaga, Mamoru Doi | Summary: In this letter we report a discovery of an ultra-luminous fast evolving transient in rest-frame UV wavelengths, MUSSES2020J, soon after its occurrence by using the Hyper Suprime-Cam (HSC) mounted on the 8.2m Subaru telescope. The […]


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The role of the cerebellum in learning to predict reward: evidence from cerebellar ataxia

Kavli Affiliate: Daphna Shohamy | Authors: Jonathan Nicholas, Christian Amlang, Chi-Ying Lin, Leila Montaser-Kouhsari, Natasha Desai, Ming-Kai Pan, Sheng-Han Kuo and Daphna Shohamy | Summary: Recent findings in animals have challenged the traditional view of the cerebellum solely as the site of motor control, suggesting that the cerebellum may also be important for learning to […]


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Prioritizing virtual screening with interpretable interaction fingerprints

Kavli Affiliate: Michael Keiser | Authors: Alexandre V Fassio, Laura Shub, Luca Ponzoni, Jessica McKinley, Matthew J O’Meara, Rafaela S Ferreira, Michael J Keiser and Raquel C de Melo Minardi | Summary: Machine learning-based drug discovery success depends on molecular representation. Yet traditional molecular fingerprints omit both the protein and pointers back to structural information […]


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A developmental pathway for epithelial-to-motoneuron transformation in C. elegans

Kavli Affiliate: Shai Shaham | Authors: Alina Rashid, Maya Tevlin, Yun Lu and Shai Shaham | Summary: Motoneurons and motoneuron-like pancreatic beta cells arise from radial glia and ductal cells, both tube-lining progenitors that share molecular regulators. To uncover programs underlying motoneuron formation, we studied a similar, cell-division-independent transformation of the C. elegans tube-lining Y […]


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