Kavli Affiliate:Allan Basbaum | Authors: Wendy W.S. Yue, Lin Yuan, Joao M. Bráz, Allan I. Basbaum and David Julius | Summary: TRPV1, a capsaicin- and heat-sensitive ion channel, is expressed by peripheral nociceptors and has been implicated in various inflammatory and neuropathic pain conditions. Although pharmacological modulation of TRPV1 has attracted therapeutic interest, their utility […]
Continue.. TRPV1 drugs alter core body temperature via central projections of primary afferent sensory neurons