Optogenetic Central Amygdala Stimulation is Highly Reinforcing and Strongly Outcompetes Fentanyl Self-Administration in Male, but not Female, Rats

Kavli Affiliate: Patricia Janak | Authors: Emma Chaloux-Pinette, Maricela Vela Mirelez-Prince, Samantha Soto, Kirtana Ananth, Xiao Tong, Vanessa Silva, Daniela Rodriguez and Patricia H Janak | Summary: The central nucleus of the amygdala plays a key role in many aspects of substance use disorders, in particular biasing behaviors toward one drug or natural reward over […]


Continue.. Optogenetic Central Amygdala Stimulation is Highly Reinforcing and Strongly Outcompetes Fentanyl Self-Administration in Male, but not Female, Rats

Cephalopod Sex Determination and its Ancient Evolutionary Origin

Kavli Affiliate: Scott Small | Authors: Gabrielle C. Coffing, Silas Tittes, Scott T. Small, Jeremea O. Songco-Casey, Denise M. Piscopo, Judit R. Pungor, Adam C Miller, Cristopher Niell and Andrew D. Kern | Summary: Octopuses, squids, and cuttlefishes – the coleoid cephalopods – are a remarkable branch in the tree of life whose members exhibit […]


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Recurrent Connectivity Shapes Spatial Coding in Hippocampal CA3 Subregions

Kavli Affiliate: Darcy Peterka and Attila Losonczy | Authors: Eunji Kong, Erfan Zabeh, Zhenrui Liao, Tiberiu S. Mihaila, Darcy S. Peterka, Caroline Wilson, Charan Santhirasegaran, Attila Losonczy and Tristan Geiller | Summary: Stable and flexible neural representations of space in the hippocampus are crucial for navigating complex environments. However, how these distinct representations emerge from […]


Continue.. Recurrent Connectivity Shapes Spatial Coding in Hippocampal CA3 Subregions

Ultrastructural correlates of circadian structural plasticity

Kavli Affiliate: Mark Ellisman | Authors: Juan I. Ispizua, Micaela Rodriguez-Caron, Francisco J. Tassara, Kim Keun-young, Catalina Insusarry Perkins, Milagros Barzi, Christian Carpio-Romero, Celia N. Hansen, Julian Gargiulo, Ezio Rosato, Horacio de la iglesia, Mark Ellisman and M. Fernanda Ceriani | Summary: The central clock in the Drosophila’s brain consists of approximately 250 neurons organized […]


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Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila

Kavli Affiliate: Mark Ellisman | Authors: Francisco Joaquín Tassara, Mariano Barella, Lourdes Simó, Mailen Folgueira, Micaela Rodríguez-Caron, Juan Ignacio Ispizua, Mark H. Ellisman, Horacio O. de la Iglesia, M. Fernanda Ceriani and Julián Gargiulo | Summary: In vivo imaging of dynamic sub-cellular brain structures in Drosophila melanogaster is key to understanding several phenomena in neuroscience. […]


Continue.. Single Objective Light Sheet Microscopy allows high-resolution in vivo brain imaging of Drosophila

Electrical Coordinated Reset Stimulation Induces Network Desynchronization in an in Vivo Model of Status Epilepticus

Kavli Affiliate: Sridevi Sarma | Authors: Daniel Ehrens, Fadi Aeed, Yara Otor, Vivek Charu, Babak Razavi, Sridevi V Sarma, Yitzhak Schiller and Peter A Tass | Summary: Epilepsy, a neurological disorder characterized by recurrent seizures, profoundly impacts individuals worldwide. Various electrical stimulation protocols have been investigated to mitigate epileptic seizures, among which Coordinated Reset (CR) […]


Continue.. Electrical Coordinated Reset Stimulation Induces Network Desynchronization in an in Vivo Model of Status Epilepticus

Resting-state connectivity modifies the effects of amyloid on cognitive and physical function: evidence for network-based cognitive reserve

Kavli Affiliate: Michael Miller | Authors: Paul J Laurienti, Stephen B Kritchevsky, Robert G Lyday, Michael E Miller, Samuel N Lockhart, Melissa M Rundle, Christina E Hugenschmidt, Jonathan H Burdette, Heather M Shappell, Haiying Chen, Laura D Baker, Blake R Neyland and Roee Holtzer | Summary: Cognitive and physical function are interrelated in aging co-occurring […]


Continue.. Resting-state connectivity modifies the effects of amyloid on cognitive and physical function: evidence for network-based cognitive reserve

A green lifetime biosensor for calcium that remains bright over its full dynamic range

Kavli Affiliate: Gaby Maimon | Authors: Franka H. van der Linden, Stephen C. Thornquist, Rick M. ter Beek, Jelle Y. Huijts, Mark A. Hink, Theodorus W.J. Gadella, Jr., Gaby Maimon and Joachim Goedhart | Summary: Fluorescent biosensors toggle between two states and for the vast majority of biosensors one state is bright and the other […]


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Dynamic modulation of social gaze by sex and familiarity in marmoset dyads

Kavli Affiliate: Anirvan Nandy | Authors: Feng Xing, Alec Graham Sheffield, Monika P. Jadi, Steve W. C. Chang and Anirvan S. Nandy | Summary: Social communication relies on the ability to perceive and interpret the direction of others’ attention, and is commonly conveyed through head orientation and gaze direction in humans and nonhuman primates. However, […]


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In vivo cell-type and brain region classification via multimodal contrastive learning

Kavli Affiliate: Liam Paninski | Authors: Han Yu, Hanrui Lyu, Ethan YiXun Xu, Charlie Windolf, Eric Kenji Lee, Fan Yang, Andrew M Shelton, Shawn Olsen, Sahar Minavi, Olivier Winter, The International Brain Laboratory, Eva L Dyer, Chandramouli Chandrasekaran, Nicholas A Steinmetz, Liam Paninski and Cole Hurwitz | Summary: Current electrophysiological approaches can track the activity […]


Continue.. In vivo cell-type and brain region classification via multimodal contrastive learning