Theory of interaction between untuned modulatory inputs and tuned sensory inputs

Kavli Affiliate: Kenneth Miller | Authors: Tuan Nguyen, Agostina Palmigiano and Kenneth D Miller | Summary: How does the brain integrate sensory inputs with non-feature-tuned signals, such as those arising from behavioral state changes or neuromodulation? Here, we show that the dynamics of disordered E/I networks with structured, feature-dependent connectivity can be well characterized by […]


Continue.. Theory of interaction between untuned modulatory inputs and tuned sensory inputs

Presynaptic vesicles supply membrane for axonal bouton enlargement during LTP

Kavli Affiliate: Terrence Sejnowski | Authors: Patrick Leavey, Lizhi Jiang, Nicole Pannullo, Clayton Santiago and Seth BlackshawLyndsey M Kirk, Guadalupe C Garcia, Dakota C Hanka, Kyle Zatyko, Thomas M Bartol, Terrence J Sejnowski and Kristen M. Harris | Summary: Long-term potentiation (LTP) induces presynaptic bouton enlargement and a reduction in the number of synaptic vesicles. […]


Continue.. Presynaptic vesicles supply membrane for axonal bouton enlargement during LTP

Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis.

Kavli Affiliate: Seth Blackshaw | Authors: Patrick Leavey, Lizhi Jiang, Nicole Pannullo, Clayton Santiago and Seth Blackshaw | Summary: The vertebrate retina serves as a model for studying neurogenesis and cell fate specification, with retinal progenitor cells following a tightly regulated temporal sequence to generate distinct cell types. Meis1 and Meis2 are transcription factors implicated […]


Continue.. Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis.

Full inter-hemispheric integration sustained by a fraction of posterior callosal fibers

Kavli Affiliate: Michael Miller | Authors: Tyler Santander, Selin Bekir, Theresa Paul, Jessica M Simonson, Valerie M Wiemer, Henri Etel Skinner, Johanna L Hopf, Anna Rada, Friedrich G Woermann, Thilo Kalbhenn, Barry Giesbrecht, Christian G Bien, Olaf Sporns, Michael S Gazzaniga, Lukas J Volz and Michael B Miller | Summary: The dynamic integration of the […]


Continue.. Full inter-hemispheric integration sustained by a fraction of posterior callosal fibers

Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

Kavli Affiliate: Seth Blackshaw | Authors: Selin Bekir, Johanna L. Hopf, Theresa Paul, Valerie M. Wiemer, Tyler Santander, Henri E. Skinner, Anna Rada, Friedrich G. Woermann, Thilo Kalbhenn, Barry Giesbrecht, Christian G. Bien, Olaf Sporns, Michael S. Gazzaniga, Lukas J. Volz and Michael B. Miller | Summary: Evolutionary adaptation to diurnal vision in ground squirrels […]


Continue.. Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels.

Dynamic convergence of autism disorder risk genes across neurodevelopment

Kavli Affiliate: Ellen J. Hoffman | Authors: Meilin Fernandez Garcia, Kayla Retallick-Townsley, Novin Balafkan, April Pruitt, Elizabeth Davidson, Yi Dai, Sarah E Fitzpatrick, Tzu-Chieh Huang, Alfred Kibowen, Jonathan Warrell, Ran Meng, Zhiyuan Chu, Annabel Sen, Sophie Cohen, Olivia Livoti, Suha Khan, Charlotte Becker, Andre Luiz Teles Silva, Jenny Liu, Grace Dossou, Jen Cheung, Sadaf Ghorbani, […]


Continue.. Dynamic convergence of autism disorder risk genes across neurodevelopment

Short-term gonadal cultures are sufficient for germline transmission in a songbird

Kavli Affiliate: Erich Jarvis | Authors: Matthew T Biegler, Elijah Harter, Asha V Sidhu, Christina Szialta, Gillian Durham, Lotem Tchernichovski, Paul Collier, Ji-Dung Luo, Wei Wang, Ryan MacIsaac, Kirubel Belay, Thomas Carroll, Anna L Keyte and Erich D Jarvis | Summary: Primordial germ cells (PGCs) are germline stem cells that develop into sperm or egg […]


Continue.. Short-term gonadal cultures are sufficient for germline transmission in a songbird

ARAP2 regulates responses to interferon-gamma by restricting SOCS1

Kavli Affiliate: Jean-Laurent Casanova | Authors: Narelle Keating, Karen Doggett, Grace Bidgood, Lizeth G Meza Guzman, Laura Dagley, Kunlun Li, Anna Gabrielyan, Carolina Alvarado, Bailey Williams, Benjamin Broomfield, Brigette Duckworth, Colin Hockings, Jumana Youssef, Evelyn Leong, Rhiannon Morris, Andrew Kueh, Alexandra Garnham, Jean-Laurent Casanova, Stephanie Boisson-Dupuis, Jeffrey Babon, Edmond Linossi, Michelle D Tate, Joanna R. […]


Continue.. ARAP2 regulates responses to interferon-gamma by restricting SOCS1

No Disconnection Syndrome after Near-Complete Callosotomy

Kavli Affiliate: Michael Miller | Authors: Selin Bekir, Johanna L. Hopf, Theresa Paul, Valerie M. Wiemer, Tyler Santander, Henri E. Skinner, Anna Rada, Friedrich G. Woermann, Thilo Kalbhenn, Barry Giesbrecht, Christian G. Bien, Olaf Sporns, Michael S. Gazzaniga, Lukas J. Volz and Michael B. Miller | Summary: Sensorimotor processing in the human brain is largely […]


Continue.. No Disconnection Syndrome after Near-Complete Callosotomy

Spatially-resolved molecular sex differences at single cell resolution in the adult human ventromedial and arcuate hypothalamus

Kavli Affiliate: Keri Martinowich | Authors: Bernard Mulvey, Yi Wang, Heena R Divecha, Svitlana V Bach, Kelsey D Montgomery, Sophia Cinquemani, Atharv Chandra, Yufeng Du, Ryan A Miller, Joel E Kleinman, Stephanie Cerceo Page, Thomas M Hyde, Keri Martinowich, Stephanie C Hicks, Kasper D Hansen and Kristen R Maynard | Summary: The hypothalamus contains multiple […]


Continue.. Spatially-resolved molecular sex differences at single cell resolution in the adult human ventromedial and arcuate hypothalamus