Adversarial domain translation networks for fast and accurate integration of large-scale atlas-level single-cell datasets

Posted by klaurent UCSD / Salk

Kavli Affiliate: Angela Wu | Authors: Jia Zhao, Gefei Wang, Jingsi Ming, Zhixiang Lin, Yang Wang, The Tabula Microcebus Consortium, Angela Ruohao Wu and Can Yang | Summary: The rapid emergence of large-scale atlas-level single-cell RNA-seq datasets presents remarkable opportunities for broad and deep biological investigations through integrative analyses. However, harmonizing such datasets requires integration […]


Continue.. Adversarial domain translation networks for fast and accurate integration of large-scale atlas-level single-cell datasets

ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis

Posted by klaurent Yale

Kavli Affiliate: Flora Vaccarino | Authors: Alexandre Jourdon, Feinan Wu, Jessica Mariani, Davide Capauto, Scott Norton, Livia Tomasini, Anahita Amiri, Milovan Suvakov, Jeremy Schreiner, Yeongjun Jang, Cindy Khanh Nguyen, Elise M Cummings, Gloria Han, Kelly Powell, Anna Szekely, James C McPartland, Kevin Pelphrey, Katarzyna Chawarska, Pamela Ventola, Alexej Abyzov and Flora M Vaccarino | Summary: […]


Continue.. ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis

On the Connection between Supermassive Black Hole and Galaxy Growth in the Reionization Epoch

Posted by klaurent Peking

Kavli Affiliate: Kohei Inayoshi | First 5 Authors: Junyao Li, John D. Silverman, Takuma Izumi, Wanqiu He, Masayuki Akiyama | Summary: The correlation between the mass of supermassive black holes (SMBHs; $mathcal{M}_{rm BH}$) and their host galaxies ($mathcal{M}_star$) in the reionization epoch provides valuable constraints on how their growth are jointly assembled in the early […]


Continue.. On the Connection between Supermassive Black Hole and Galaxy Growth in the Reionization Epoch

Absorption Variability of the Highly Obscured Active Galactic Nucleus NGC 4507

Posted by klaurent Peking

Kavli Affiliate: Claudio Ricci | First 5 Authors: Arghajit Jana, Claudio Ricci, Sachindra Naik, Atsushi Tanimoto, Neeraj Kumari | Summary: We present a detailed study of the highly obscured active galaxy NGC 4507, performed using four Nuclear Spectroscopic Telescope Array (NuSTAR) observations carried out between May and August in 2015 (~ 130 ks in total). […]


Continue.. Absorption Variability of the Highly Obscured Active Galactic Nucleus NGC 4507

Persistent postnatal migration of interneurons into the human entorhinal cortex

Posted by klaurent UCSF

Kavli Affiliate: Arturo Alvarez-Buylla | Authors: Marcos Assis Nascimento, Sean Biagiotti, Vicente Herranz-Perez, Raymund Bueno, Chun Jimmie Ye, Taylor Abel, Juan S Rubio Moll, Jose Manuel Garcia-Verdugo, Eric J. Huang, Arturo Alvarez-Buylla and Shawn F Sorrells | Summary: The entorhinal cortex (EC) is a highly-interconnected hub for multisensory integration and memory processing1-3, containing diverse neuronal […]


Continue.. Persistent postnatal migration of interneurons into the human entorhinal cortex

KAT5 activity regulates G0-like states in human gliomas

Posted by klaurent Hopkins

Kavli Affiliate: Jin Kang | Authors: Anca Mihalas, Sonali Arora, Samantha O’Connor, Heather Feldman, John Bassett, Kelly Mitchell, Kang Jin, Pia Hoellerbauer, Melissa Ling, Wesley Jenkins, Megan Kufeld, Philip Corrin, Lucas Carter, Bruce J Aronow, Christopher J Plaisier, Anoop Patel and PATRICK PADDISON | Summary: In solid tumors, G0-like cell populations likely play important roles […]


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Galactic angular momentum in the IllustrisTNG simulation — I. Connection to morphology, halo spin, and black hole mass

Posted by klaurent MIT

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Vicente Rodriguez-Gomez, Shy Genel, S. Michael Fall, Annalisa Pillepich, Marc Huertas-Company | Summary: We use the TNG100 simulation of the IllustrisTNG project to investigate the stellar specific angular momenta ($j_{ast}$) of $sim$12~000 central galaxies at $z=0$ in a full cosmological context, with stellar masses ($M_{ast}$) ranging from […]


Continue.. Galactic angular momentum in the IllustrisTNG simulation — I. Connection to morphology, halo spin, and black hole mass

Advancing the Landscape of Multimessenger Science in the Next Decade

Posted by klaurent Stanford

Kavli Affiliate: Nicola Omodei | First 5 Authors: Kristi Engel, Tiffany Lewis, Marco Stein Muzio, Tonia M. Venters, Markus Ahlers | Summary: The last decade has brought about a profound transformation in multimessenger science. Ten years ago, facilities had been built or were under construction that would eventually discover the nature of objects in our […]


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Advancing the Landscape of Multimessenger Science in the Next Decade

Posted by klaurent MIT

Kavli Affiliate: David Shoemaker | First 5 Authors: Kristi Engel, Tiffany Lewis, Marco Stein Muzio, Tonia M. Venters, Markus Ahlers | Summary: The last decade has brought about a profound transformation in multimessenger science. Ten years ago, facilities had been built or were under construction that would eventually discover the nature of objects in our […]


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Scalar-mediated dark matter model at colliders and gravitational wave detectors — A White paper for Snowmass 2021

Posted by klaurent Tokyo

Kavli Affiliate: Jia Liu | First 5 Authors: Jia Liu, Xiao-Ping Wang, Ke-Pan Xie, , | Summary: The weakly interacting massive particles (WIMPs) have been the most popular particle dark matter (DM) candidate for the last several decades, and it is well known that WIMP can be probed via the direct, indirect and collider experiments. […]


Continue.. Scalar-mediated dark matter model at colliders and gravitational wave detectors — A White paper for Snowmass 2021