Feasibility Analyses and Experimental Confirmation of Dove Prism Based Dual-fiberscope Rotary Joint

Posted by klaurent Hopkins

Kavli Affiliate: Xingde Li | Authors: Yuehan Liu, Hyeon-Cheol Park, Haolin Zhang and Xingde Li | Summary: Abstract Two-photon fluorescence microscopy has enjoyed its wide adoption in neuroscience. Head-mounted miniaturized fiberscopes offered an exciting opportunity for enabling neural imaging in freely-behaving animals with high 3D resolution. Here we propose a dual-fiberscope rotary joint based on […]


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Validation of TOI-1221 b, a warm sub-Neptune exhibiting TTVs around a Sun-like star

Posted by klaurent MIT

Kavli Affiliate: Roland Vanderspek | First 5 Authors: Christopher R. Mann, David Lafrenière, Diana Dragomir, Samuel N. Quinn, Thiam-Guan Tan | Summary: We present a successful validation of the long-period ($91.68278^{+0.00032}_{-0.00041}$ days) transiting sub-Neptune planet TOI-1221 b (TIC 349095149.01) around a Sun-like (m$_{rm V}$=10.5) star. We combine {it TESS} light curve measurements and ground-based time-series […]


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Mitf is a Schwann Cell Sensor of Axonal Integrity that Drives Nerve Repair

Posted by klaurent UCSD / Salk

Kavli Affiliate: Samuel Pfaff | Authors: Lydia Daboussi, Giancarlo Costaguta, Miriam Gullo, Veronica Pessino, Brendan O’Leary, Karen Lettieri, Shawn Driscoll and Samuel L. Pfaff | Summary: Abstract Schwann cells respond to acute axon damage by transiently transdifferentiating into specialized repair cells that restore sensorimotor function. However, the molecular systems controlling repair cell formation and function […]


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Report of the Topical Group on Physics Beyond the Standard Model at Energy Frontier for Snowmass 2021

Posted by Chicago

Kavli Affiliate: Marcela Carena | First 5 Authors: Tulika Bose, Antonio Boveia, Caterina Doglioni, Simone Pagan Griso, James Hirschauer | Summary: This is the Snowmass2021 Energy Frontier (EF) Beyond the Standard Model (BSM) report. It combines the EF topical group reports of EF08 (Model-specific explorations), EF09 (More general explorations), and EF10 (Dark Matter at Colliders). […]


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The Role of the Hubble Scale in the Weak Lensing vs. CMB Tension

Posted by klaurent Chicago

Kavli Affiliate: Wayne Hu | First 5 Authors: Lucas F. Secco, Tanvi Karwal, Wayne Hu, Elisabeth Krause, | Summary: We explore a re-parameterization of the lensing amplitude tension between weak lensing (WL) and cosmic microwave background (CMB) data and its implications for a joint resolution with the Hubble tension. Specifically, we focus on the lensing […]


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Role of the Hubble Scale in the Weak Lensing vs. CMB Tension

Posted by Chicago

Kavli Affiliate: Wayne Hu | First 5 Authors: Lucas F. Secco, Tanvi Karwal, Wayne Hu, Elisabeth Krause, | Summary: We explore a re-parameterization of the lensing amplitude tension between weak lensing (WL) and cosmic microwave background (CMB) data and its implications for a joint resolution with the Hubble tension. Specifically, we focus on the lensing […]


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A New Method for Finding Nearby White Dwarf Exoplanets and Detecting Biosignatures

Posted by klaurent MIT

Kavli Affiliate: Andrew Vanderburg | First 5 Authors: Mary Anne Limbach, Andrew Vanderburg, Kevin B. Stevenson, Simon Blouin, Caroline Morley | Summary: We demonstrate that the James Webb Space Telescope (JWST) can detect infrared (IR) excess from the blended light spectral energy distribution of spatially unresolved terrestrial exoplanets orbiting nearby white dwarfs. We find that […]


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Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes

Posted by klaurent Hopkins

Kavli Affiliate: Michael Miller | Authors: Han Zhu, Gaowei Wang, Kim-Vy Nguyen-Ngoc, Dongsu Kim, Michael Miller, Georgina Goss, Jenna Kovsky, Austin R Harrington, Diane Saunders, Rebecca Melton, Alvin C Powers, Sebastian Preissl, Francesca M Spagnoli, Kyle J Gaulton and Maike Sander | Summary: Abstract Pancreatic islet cells derived from human pluripotent stem cells hold great […]


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Ultrastructure of synaptic connectivity within sub-regions of the SCN revealed by genetically encoded EM tag and SBEM

Posted by klaurent UCSD / Salk

Kavli Affiliate: Mark Ellisman | Authors: Hugo Calligaro, Azarin Shoghi, Xinyue Chen, Keun-Young Kim, Yu Hsin Liu, Brian Khov, Benjamin Finander, Hiep Le, Mark H Ellisman and Satchidananda Panda | Summary: Abstract The suprachiasmatic nucleus (SCN) in the hypothalamus of the vertebrate brain is the central pacemaker regulating circadian rhythmicity throughout the body. The SCN […]


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Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells

Posted by klaurent UCSD / Salk

Kavli Affiliate: Fred Gage | Authors: Sarah L Parylak, Fan Qiu, Sara B Linker, Iryna S Gallina, Christina K Lim, David Preciado, Aidan H McDonald and Fred H Gage | Summary: Abstract Immature dentate granule cells (DGCs) generated in the hippocampus during adulthood are believed to play a unique role in dentate gyrus function. Although […]


Continue.. Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells