Isolation and Lipidomic Profiling of Neuronal Lipid Droplets: Unveiling the Lipid Landscape for insights into Neurodegenerative Disorders

Posted by dbos Rockefeller

Kavli Affiliate: Timothy A. Ryan | Authors: Mukesh Kumar, Justin Knapp, Kallol Gupta and Timothy A Ryan | Summary: Recent advances have expanded the role of lipid droplets (LDs) beyond passive lipid storage, implicating their involvement in various metabolic processes across mammalian tissues. Neuronal LDs, long debated in existence, have been identified in several neural […]


Continue.. Isolation and Lipidomic Profiling of Neuronal Lipid Droplets: Unveiling the Lipid Landscape for insights into Neurodegenerative Disorders

Target Selection and Sample Characterization for the DESI LOW-Z Secondary Target Program

Posted by klaurent Stanford

Kavli Affiliate: Risa H. Wechsler | First 5 Authors: Elise Darragh-Ford, John F. Wu, Yao-Yuan Mao, Risa H. Wechsler, Marla Geha | Summary: We introduce the DESI LOW-Z Secondary Target Survey, which combines the wide-area capabilities of the Dark Energy Spectroscopic Instrument (DESI) with an efficient, low-redshift target selection method. Our selection consists of a […]


Continue.. Target Selection and Sample Characterization for the DESI LOW-Z Secondary Target Program

Cosmic Reionization On Computers: Statistics, Physical Properties and Environment of Lyman Limit Systems at $zsim6$

Posted by Chicago

Kavli Affiliate: Nickolay Y. Gnedin | First 5 Authors: Jiawen Fan, Hanjue Zhu, Camille Avestruz, Nickolay Y. Gnedin, | Summary: Lyman Limit Systems (LLSs) are dense hydrogen clouds with high enough HI column densities ($N_{rm HI}$) to absorb Lyman continuum photons emitted from distant quasars. Their high column densities imply an origin in dense environments; […]


Continue.. Cosmic Reionization On Computers: Statistics, Physical Properties and Environment of Lyman Limit Systems at $zsim6$

Cosmic Reionization On Computers: Statistics, Physical Properties and Environment of Lyman Limit Systems at $zsim6$

Posted by Chicago

Kavli Affiliate: Nickolay Y. Gnedin | First 5 Authors: Jiawen Fan, Hanjue Zhu, Camille Avestruz, Nickolay Y. Gnedin, | Summary: Lyman Limit Systems (LLSs) are dense hydrogen clouds with high enough HI column densities ($N_{rm HI}$) to absorb Lyman continuum photons emitted from distant quasars. Their high column densities imply an origin in dense environments; […]


Continue.. Cosmic Reionization On Computers: Statistics, Physical Properties and Environment of Lyman Limit Systems at $zsim6$

Cosmic Reionization On Computers: Statistics, Physical Properties and Environment of Lyman Limit Systems at $zsim6$

Posted by Chicago

Kavli Affiliate: Nickolay Y. Gnedin | First 5 Authors: Jiawen Fan, Hanjue Zhu, Camille Avestruz, Nickolay Y. Gnedin, | Summary: Lyman limit systems (LLSs) are dense hydrogen clouds with high enough HI column densities to absorb Lyman continuum photons emitted from distant quasars. Their high column densities imply an origin in dense environments; however, the […]


Continue.. Cosmic Reionization On Computers: Statistics, Physical Properties and Environment of Lyman Limit Systems at $zsim6$

COOL-LAMPS IV: A Sample of Bright Strongly-Lensed Galaxies at $3 < z < 4$

Posted by Chicago

Kavli Affiliate: Michael D. Gladders | First 5 Authors: Yunchong Zhang, Viraj Manwadkar, Michael D. Gladders, Gourav Khullar, Håkon Dahle | Summary: We report the discovery of five bright strong gravitationally lensed galaxies at $3 < z < 4$: COOLJ0101$+$2055 ($z = 3.459$), COOLJ0104$-$0757 ($z = 3.480$), COOLJ0145$+$1018 ($z = 3.310$), COOLJ0516$-$2208 ($z = 3.549$), […]


Continue.. COOL-LAMPS IV: A Sample of Bright Strongly-Lensed Galaxies at $3 < z < 4$

Architectures for Multinode Superconducting Quantum Computers

Posted by klaurent Caltech

Kavli Affiliate: Andrei Faraon | First 5 Authors: James Ang, Gabriella Carini, Yanzhu Chen, Isaac Chuang, Michael Austin DeMarco | Summary: Many proposals to scale quantum technology rely on modular or distributed designs where individual quantum processors, called nodes, are linked together to form one large multinode quantum computer (MNQC). One scalable method to construct […]


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A Measurement of the CMB Temperature Power Spectrum and Constraints on Cosmology from the SPT-3G 2018 TT/TE/EE Data Set

Posted by Stanford

Kavli Affiliate: Chao-Lin Kuo | First 5 Authors: L. Balkenhol, D. Dutcher, A. Spurio Mancini, A. Doussot, K. Benabed | Summary: We present a sample-variance-limited measurement of the temperature power spectrum ($TT$) of the cosmic microwave background (CMB) using observations of a $sim! 1500 ,mathrm{deg}^2$ field made by SPT-3G in 2018. We report multifrequency power […]


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Upregulated extracellular matrix-related genes and impaired synaptic activity in dopaminergic and hippocampal neurons derived from Parkinson’s disease patients with PINK1 and PARK2 mutations

Posted by klaurent UCSD / Salk

Kavli Affiliate: Fred Gage | Authors: Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H. Gage and Shani Stern | Summary: Abstract Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease. Primary symptoms of PD arise with the loss of dopaminergic (DA) neurons in […]


Continue.. Upregulated extracellular matrix-related genes and impaired synaptic activity in dopaminergic and hippocampal neurons derived from Parkinson’s disease patients with PINK1 and PARK2 mutations

Two types of locus coeruleus norepinephrine neurons drive reinforcement learning

Posted by klaurent Hopkins

Kavli Affiliate: Jeremiah Cohen | Authors: Zhixiao Su and Jeremiah Y. Cohen | Summary: Abstract The cerebral cortex generates flexible behavior by learning. Reinforcement learning is thought to be driven by error signals in midbrain dopamine neurons. However, they project more densely to basal ganglia than cortex, leaving open the possibility of another source of […]


Continue.. Two types of locus coeruleus norepinephrine neurons drive reinforcement learning