Genome Organization with CUT and Tag (GO-CaT) identifies substructure and maturation of lamina-associated domains in neurons of the developing human brain

Posted by dbos This Week: Neuroscience, UCSF

Kavli Affiliate: Arnold R. Kriegstein | Authors: Chujing Zhang, Eugene Gil, Sajad Hamid Ahanger, Mingcong Li, Li Wang, Jingjing Li, Arnold Kriegstein and Daniel Lim | Summary: Approximately 30-40% of the human genome is anchored to the nuclear lamina through variably sized (10 kb–10 Mb) lamina-associated domains (LADs). Previous work in cultured murine and human […]


Continue.. Genome Organization with CUT and Tag (GO-CaT) identifies substructure and maturation of lamina-associated domains in neurons of the developing human brain

Signatures of black hole seeding in the local Universe: Predictions from the BRAHMA cosmological simulations

Posted by dbos MIT, This Week: Astrophysics

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Aklant K Bhowmick, Laura Blecha, Paul Torrey, Rachel S Somerville, Luke Zoltan Kelley | Summary: The first "seeds" of supermassive black holes (BHs) continue to be an outstanding puzzle, and it is currently unclear whether the imprints of early seed formation survive today. Here we examine the […]


Continue.. Signatures of black hole seeding in the local Universe: Predictions from the BRAHMA cosmological simulations

Rapid Rotation of Polarization Orientations in PSR B1919+21’s Single Pulses: Implications On Pulsar’s Magnetospheric Dynamics

Posted by dbos Peking, This Week: Astrophysics

Kavli Affiliate: Kejia Lee | First 5 Authors: Shunshun Cao, Jinchen Jiang, Jaroslaw Dyks, Kejia Lee, Jiguang Lu | Summary: We analyse and model rapid rotations of polarization orientations in PSR B1919+21’s single pulses, based on FAST observation data. In more than one third of B1919+21’s single pulses, polarization angle (PA) is found to rotate […]


Continue.. Rapid Rotation of Polarization Orientations in PSR B1919+21’s Single Pulses: Implications On Pulsar’s Magnetospheric Dynamics

A Short-lived Rejuvenation during the Decades-long Changing-look Transition in the Nucleus of Mrk 1018

Posted by dbos Peking, This Week: Astrophysics

Kavli Affiliate: Luis C. Ho | First 5 Authors: Kai-Xing Lu, Yan-Rong Li, Qingwen Wu, Luis C. Ho, Zhi-Xiang Zhang | Summary: Changing-look active galactic nuclei (CL-AGNs), characterized by emerging or disappearing of broad lines accompanied with extreme continuum flux variability, have drawn much attention for their potential of revealing physical processes underlying AGN evolution. […]


Continue.. A Short-lived Rejuvenation during the Decades-long Changing-look Transition in the Nucleus of Mrk 1018

A Trade-Off Between Path Entanglement and Quantum Sensitivity

Posted by dbos MIT, This Week: Astrophysics

Kavli Affiliate: Nergis Mavalvala | First 5 Authors: Benjamin Lou, Hudson A. Loughlin, Nergis Mavalvala, , | Summary: Entanglement often increases quantum measurement schemes’ sensitivity. However, we find that in precision measurements with zero-mean Gaussian states, such as squeezed states, entanglement between different paths degrades measurement sensitivity. We prove an inverse relationship between entanglement entropy […]


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The Higgs-Amplitude mode in the optical conductivity in the presence of a supercurrent: Gauge invariant forumulation

Posted by dbos Peking, This Week: Astrophysics

Kavli Affiliate: Ke Wang | First 5 Authors: Ke Wang, Rufus Boyack, K. Levin, , | Summary: Observing the amplitude-Higgs mode in superconductors has been a central challenge in condensed matter physics. Unlike the phase mode in the electromagnetic (EM) response, the amplitude mode is not needed to satisfy gauge invariance. Indeed, it couples to […]


Continue.. The Higgs-Amplitude mode in the optical conductivity in the presence of a supercurrent: Gauge invariant forumulation

The Galaxy Activity, Torus, and Outflow Survey (GATOS). VII. The 20-214 $μ$m imaging atlas of active galactic nuclei using SOFIA

Posted by dbos Peking, This Week: Astrophysics

Kavli Affiliate: Claudio Ricci | First 5 Authors: Lindsay Fuller, Enrique Lopez-Rodriguez, Ismael Garcia-Bernete, Cristina Ramos Almeida, Almudena Alonso-Herrero | Summary: We present a 19.7 – 214 $mu$m imaging atlas of local (4 – 181 Mpc; median 43 Mpc) active galactic nuclei (AGN) observed with FORCAST and HAWC+ on board the SOFIA telescope with angular […]


Continue.. The Galaxy Activity, Torus, and Outflow Survey (GATOS). VII. The 20-214 $μ$m imaging atlas of active galactic nuclei using SOFIA

Multi-sample non-negative spatial factorization

Posted by dbos Hopkins, This Week: Neuroscience

Kavli Affiliate: Loyal Goff | Authors: Yi Wang, Kyla Woyshner, Chaichontat Sriworarat, Genevieve Stein-O’Brien, Loyal A Goff and Kasper D Hansen | Summary: Analyzing multi-sample spatial transcriptomics data requires accounting for biological variation. We present multi-sample non-negative spatial factorization (mNSF), an alignment-free framework extending single-sample spatial factorization (NSF) to multi-sample datasets. mNSF incorporates sample-specific spatial […]


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A New Moiré Platform Based on M-Point Twisting

Posted by dbos Cornell, This Week: Nanoscience

Kavli Affiliate: Jie Shan | First 5 Authors: Dumitru Călugăru, Yi Jiang, Haoyu Hu, Hanqi Pi, Jiabin Yu | Summary: We introduce a new class of moir’e systems and materials based on monolayers with triangular lattices and low-energy states at the M points of the Brillouin zone. These M-point moir’e materials are fundamentally distinct from […]


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A giant planet transiting a 3-Myr protostar with a misaligned disk

Posted by dbos MIT, This Week: Astrophysics

Kavli Affiliate: Sara Seager | First 5 Authors: Madyson G. Barber, Andrew W. Mann, Andrew Vanderburg, Daniel Krolikowski, Adam Kraus | Summary: Astronomers have found more than a dozen planets transiting 10-40 million year old stars, but even younger transiting planets have remained elusive. A possible reason for the lack of such discoveries is that […]


Continue.. A giant planet transiting a 3-Myr protostar with a misaligned disk