Neurofeedback training can modulate task-relevant memory replay in rats

Kavli Affiliate: Loren Frank | Authors: Anna K Gillespie, Daniela A Astudillo Maya, Eric L. Denovellis, Sachi Desse and Loren M Frank | Summary: Hippocampal replay – the time-compressed, sequential reactivation of ensembles of neurons related to past experience – is a key neural mechanism of memory consolidation. Replay typically coincides with a characteristic pattern […]


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A foundational atlas of autism protein interactions reveals molecular convergence

Kavli Affiliate: Jeremy Willsey | Authors: Belinda Wang, Rasika Vartak, Yefim Zaltsman, Zun Zar Chi Naing, Kelsey M Hennick, Benjamin J Polacco, Ali Bashir, Manon Eckhardt, Mehdi Bouhaddou, Jiewei Xu, Nawei Sun, Micaela Lasser, Yuan Zhou, Keelan Z Guiley, Una Chan, Julia A Kaye, Prachi Khare, Sam Drake, Vanessa Drury, David F Burke, Silvano Gonzalez, […]


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Protein property prediction based on local environment by 3D equivariant convolutional neural networks

Kavli Affiliate: Yifan Cheng | Authors: He Chen, Yifan Cheng, Jianqiang Dong, Jie Mao, Xin Wang, Yuan Gao, Yuchao Li, Chengzhi Wang and Qiong Wu | Summary: Predicting the properties of proteins is an important procedure in protein engineering. It determines the subspace of mutations for protein modifications, which is critical to the success of […]


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An experimental census of retrons for DNA production and genome editing

Kavli Affiliate: Seth Shipman | Authors: Asim G. Khan, Matías Rojas-Montero, Alejandro González-Delgado, Santiago C. Lopez, Rebecca F. Fang and Seth L. Shipman | Summary: Abstract Retrons are bacterial immune systems that use reverse transcribed DNA as a detector of phage infection. They are also increasingly deployed as a component of biotechnology. For genome editing, […]


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Regional specialization manifests in the reliability of neural population codes

Kavli Affiliate: Razi Haque Christoph Kirst Loren Frank | Authors: Kyu Hyun Lee, Eric L. Denovellis, Ryan Ly, Jeremy Magland, Jeff Soules, Alison E Comrie, Daniel P Gramling, Jennifer A Guidera, Rhino Nevers, Philip Adenekan, Chris Brozdowski, Sam Bray, Emily Monroe, Ji Hyun Bak, Michael Coulter, Xulu Sun, Andrew Tritt, Oliver Oliver Ruebel, Thinh Nguyen, […]


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Molecular and cellular dynamics of the developing human neocortex at single-cell resolution

Kavli Affiliate: Xin Duan, Arnold R. Kriegstein, and Xin Duan | Authors: Li Wang, Cheng Wang, Juan A. Moriano, Songcang Chen, Shaobo Zhang, Tanzila Mukhtar, Shaohui Wang, Arantxa Cebrian-Silla, Qiuli Bi, Jonathan J. Augustin, Lilian G. de Oliveira, Mengyi Song, Xinxin Ge, Guolong Zuo, Mercedes F. Paredes, Eric J. Huang, Arturo Alvarez-Buylla, Xin Duan, Jingjing […]


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Comment on ‘Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation’

Kavli Affiliate: Joshua Berke | Authors: James Taniguchi, Riccardo Melani, Lynne Chantranupong, Michelle J Wen, Ali Mohebi, Joshua D Berke, Bernardo L Sabatini and Nicolas X Tritsch | Summary: Acetylcholine is widely believed to modulate the release of dopamine in the striatum of mammals. Experiments in brain slices clearly show that synchronous activation of striatal […]


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Homological landscape of human brain functional sub-circuits

Kavli Affiliate: Alan David Kaplan | Authors: Duy Duong-Tran, Ralph Kaufmann, Jiong Chen, Xuan Wang, Sumita Garai, Frederick Xu, Jingxuan Bao, Enrico Amico, Alan David Kaplan, Giovanni Petri, Joaquin Goni, Yize Zhao and Li Shen | Summary: Human whole-brain functional connectivity networks have been shown to exhibit both local/quasilocal (e.g., set of functional sub-circuits induced […]


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Neurotrophin NT-4/5 Promotes Structural Changes in Neurons of the Developing Visual Cortex

Kavli Affiliate: Michael Stryker | Authors: Antonella Antonini, Sheri L Harris and Michael P Stryker | Summary: Current hypotheses on the mechanisms underlying the development and plasticity of the ocular dominance system through competitive interactions between pathways serving the two eyes strongly suggest the involvement of neurotrophins and their high affinity receptors. In the cat, […]


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Predicting stop codon reassignment improves functional annotation of bacteriophages

Kavli Affiliate: Robert Edwards | Authors: Ryan Cook, Andrea Telatin, George Bouras, Antonio Pedro Camargo, Martin Larralde, Robert A Edwards and Evelien M Adriaenssens | Summary: The majority of bacteriophage diversity remains uncharacterised, and new intriguing mechanisms of their biology are being continually described. Members of some phage lineages, such as the Crassvirales, repurpose stop […]


Continue.. Predicting stop codon reassignment improves functional annotation of bacteriophages