Kavli Affiliate: Jean-Laurent Casanova, Charles M. Rice | Authors: Jeremie Le Pen, Gabrielle Paniccia, Michael Bauer, H.-Heinrich Hoffmann, Volker Kinast, Marcela Moncada-Velez, Ana Pinharanda, Inna Ricardo-Lax, Ansgar F Stenzel, Edwin A Rosado-Olivieri, Alison W Ashbrook, Kenneth H Dinnon, William Doyle, Catherine Freije, Seon-Hui Hong, Danyel Lee, Tyler Lewy, Joseph M Luna, Avery Peace, Carltin Schmidt, […]

Kavli Affiliate: Mary E. Hatten | Authors: Michalina Hanzel, Kayla Fernando, Susan E Maloney, Shioaching Gong, Kärt Mätlik, Jiajia Zhao, H Amalia Pasolli, Søren Heissel, Joseph D Dougherty, Court Hull and Mary E Hatten | Summary: Astrotactin 2 (ASTN2) is a transmembrane neuronal protein highly expressed in the cerebellum that functions in receptor trafficking and […]

Kavli Affiliate: Timothy A. Ryan, Timothy Brown | Authors: Ryan J Farrell, Kirsten G Bredvik, Michael Blake Hoppa, S Thomas Hennegan, Timothy A Brown and Timothy A Ryan | Summary: The endoplasmic reticulum (ER) is an important regulator of Ca2+ in cells and dysregulation of ER calcium homeostasis can lead to numerous pathologies. Understanding how […]

Kavli Affiliate: Li Zhao | Authors: Xin Hou, Yong He, Pan Fang, Shi-Qiang Mei, Zan Xu, Wei-Chen Wu, Jun-Hua Tian, Shun Zhang, Zhen-Yu Zeng, Qin-Yu Gou, Gen-Yang Xin, Shi-Jia Le, Yin-Yue Xia, Yu-Lan Zhou, Feng-Ming Hui, Yuan-Fei Pan, John-Sebastian Eden, Zhao-Hui Yang, Chong Han, Yue-Long Shu, Deyin Guo, Jun Li, Edward C Holmes, Zhao-Rong Li […]

Kavli Affiliate: Michael W. Young | Authors: Waruna Thotamune, Sithurandi Ubeysinghe, Kendra Kumar Shrestha, Mahmoud Elhusse Mostafa, Michael C Young and Ajith Karunarathne | Summary: Beta-adrenergic receptors (βARs) are G protein-coupled receptors (GPCRs) that mediate catecholamine-induced stress responses, such as heart rate increase and bronchodilation. In addition to signals from the cell surface, βARs also […]

Kavli Affiliate: Daniel Kronauer | Authors: Taylor Hart, Lindsey E. Lopes, Dominic D. Frank and Daniel J.C. Kronauer | Summary: While the neural basis of age-related decline has been extensively studied (1–3), less is known about changes in neural function during the pre-senescent stages of adulthood. Adult neural plasticity is likely a key factor in […]

Kavli Affiliate: Daniel Kronauer | Authors: Kip D Lacy, Taylor Hart and Daniel J.C. Kronauer | Summary: According to Mendel’s second law, chromosomes segregate randomly in meiosis. Non-random segregation is primarily known for cases of selfish meiotic drive in females, in which particular alleles bias their own transmission into the oocyte1,2. Here, we report a […]

Kavli Affiliate: Erich Jarvis | Authors: Jun Ishigohoka, Karen Bascón-Cardozo, Andrea Bours, Janina Fuß, Arang Rhie, Jacquelyn Mountcastle, Bettina Haase, William Chow, Joanna Collins, Kerstin Howe, Marcela Uliano-Silva, Olivier Fedrigo, Erich D. Jarvis, Javier Pérez-Tris, Juan Carlos Illera and Miriam Liedvogel | Summary: Genetic variation of the entire genome represents population structure, yet individual loci […]

Kavli Affiliate: Erich Jarvis | Authors: Elena N Waidmann, Victor HY Yang, William C Doyle and Erich D Jarvis | Summary: Vocal communication is a major component of animal social behavior. Vocalizations can be learned or innate, and can convey a variety of signals, including territorial limits, the presence of predators, or courtship intent. Mouse […]

Kavli Affiliate: Erich Jarvis | Authors: César D M Vargas, Rajvi K Agravat, Elena N Waidmann, Christodoulos Bochalis, Hector Bermudez, Theodoros Giannakopoulos and Erich D Jarvis | Summary: Vocalization is a complex behavior ranging from fully innate to advanced vocal learning. Vocal learning species possess a vocal primary motor cortex (M1) region that makes direct […]