Kavli Affiliate: Li Zhao | Authors: Zhao Li, Aaron James and Shengxuan Li | Summary: Background Reference catalogs such as GENCODE capture most stably expressed mammalian genes but may not include condition-restricted or low-abundance transcripts. Reads supporting unannotated intergenic splice junctions are generally absent from annotation-restricted gene-count matrices; transcript assemblers may reconstruct a subset as novel […]

Kavli Affiliate: A. James Hudspeth | Authors: Swarna Jeewajee, Francesco Gianoli, Maria Jussila, Brian Ciruna, Aaron Steiner, Adrian Jacobo and Albert James Hudspeth | Summary: The conserved core planar cell polarity (PCP) pathway orients cells and subcellular structures within an epithelium through asymmetric protein localization and intercellular communication(1–4). In vestibular organs and lateral-line neuromasts, mechanosensory […]

Kavli Affiliate: A. James Hudspeth | Authors: Teng Han, Zhen Sun, Matthew Lange, Y Zoe Cho, Patrick Mcgillivray, Maren Buttner, Nathaniel R Kastan, Subhiksha Nandakumar, Huiyong Zhao, Sanyukta Oak, Linda Fong, Wenfei Kang, Ning Fan, Jimmy Zhao, Nazifa Salsabeel, Harmanpreet Kaur, Ninghui Mao, Qing Chang, Eric Rosiek, Eric Chan, Murray Tipping, Nikolaus Schultz, Pierre-Jacques Hamard, […]

Kavli Affiliate: Vanessa Ruta | Authors: Navid Paknejad, Dragana Nesic, Beth Graczyk, Jackson Rogow, Mackenzie A. Yedlin, Chidera Udedibia, Joel Butterwick and Vanessa Ruta | Summary: Insects detect the chemical world using a large family of odorant-gated ion channels, each formed from a variable odorant-binding subunit (OR) and a single conserved co-receptor Orco. This modular […]

Kavli Affiliate: Yifan Cheng | Authors: Maureen A McGargill, Beiyun C Liu, Michael S Kuhns, Daniel Mucida, Isabella Rauch, Lauren B Rodda, Meghan A Koch, Hugo Gonzalez Velozo, Ken Cadwell, Tanya S Freedman, Tiffany C Scharschmidt, Richard Sever, Jose Ordovas-Montanes, Sara Suliman, Andrew Oberst, Brooke Runnette and Matthew F Krummel | Summary: Peer review serves […]

Kavli Affiliate: Erich Jarvis | Authors: Christopher C. Kyriazis, Stefanie Grosser, Yasmin Foster, Bryce Masuda, Alison M. Flanagan, Jennifer Balacco, Erin Datlof, Olivier Fedrigo, Giulio Formenti, Catherine E. Grueber, Jacqueline A. Robinson, Jolene T. Sutton, Alan Tracey, Jonathan M.D. Wood, Erich D. Jarvis, Oliver A. Ryder, Bruce C. Robertson and Aryn P. Wilder | Summary: […]

Kavli Affiliate: Charles M. Rice | Authors: Antonis Athanasiadis, Georgios Dangas, Ansgar F. Stenzel, Paul Park, Anthi Maslarinou, Evgenia Moschogianni, Allan Henrique Depieri Cataneo, Catherine A Freije, Yichen Zhou, Kenneth C Levenson, Corrine Quirk, Chenhui Zou, William Matthew Schneider, Adriano Aguzzi, Charles M Rice, Ype P De Jong and Eleftherios Michailidis | Summary: More than […]

Kavli Affiliate: Li Zhao | Authors: Zhao Li, Aaron James and Shengxuan Li | Summary: Background Highly variable gene (HVG) selection begins almost every single-cell RNA-seq analysis. While ranking formulas have been compared extensively, the integer gene budget at which any ranking must be truncated is typically left to the user and habitually fixed near 2,000. […]

Kavli Affiliate: Erich Jarvis | Authors: Josephine R Paris, Linelle Abueg, Sarah Pelan, Ying Sims, Tatiana Tilley, Jacquelyn Mountcastle, Jennifer Balacco, Brian O’Toole, Olivier Fedrigo, Giulio Formenti, Erich D Jarvis, Daniele Canestrelli and Daniele Salvi | Summary: The European leaf-toed gecko (Euleptes europaea) is a small, nocturnal gecko endemic to the western Mediterranean. As a […]

Kavli Affiliate: Jean-Laurent Casanova | Authors: Diana Olguín Calderón, Laura E. Kilpatrick, Clément Conil, Quentin Philippot, Masato Ogishi, Joseph Vellutini, Ji Eun Han, Narelle Keating, Hailun Li, Geetha Rao, Jonathan Bohlen, Charles S. Lay, Simon Platt, Gaspard Kerner, Elsa Feredj, Jessica N. Peel, Mana Momenilandi, Yoann Seeleuthner, Candice Lainé, Camille Soudée, Claire Leloup, Cecile Debuisson, […]