Gut bacteria-derived succinate induces enteric nervous system regeneration

Kavli Affiliate: Daniel Mucida | Authors: Begüm Aydin, Izabela Mamede, Joana Cardoso, Julia Deere, Yelina Alvarez, Shanshan Qiao, Ved P. Sharma, Marissa A. Scavuzzo, Gregory P. Donaldson, Chun-Jun Guo and Daniel Mucida | Summary: Enteric neurons control gut physiology by regulating peristalsis, nutrient absorption, and secretion. Disruptions in microbial communities caused by antibiotics or enteric […]


Continue.. Gut bacteria-derived succinate induces enteric nervous system regeneration

Complete sequencing of ape genomes

Kavli Affiliate: Erich Jarvis | Authors: DongAhn Yoo, Arang Rhie, Prajna Hebbar, Francesca Antonacci, Glennis A. Logsdon, Steven J. Solar, Dmitry Antipov, Brandon D. Pickett, Yana Safonova, Francesco Montinaro, Yanting Luo, Joanna Malukiewicz, Jessica M. Storer, Jiadong Lin, Abigail N. Sequeira, Riley J. Mangan, Glenn Hickey, Graciela Monfort Anez, Parithi Balachandran, Anton Bankevich, Christine R. […]


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Quantifying transcriptome turnover on phylogenies by modeling gene expression as a binary trait

Kavli Affiliate: Li Zhao | Authors: Ammon Thompson, Michael R. May, Ben Hopkins, Nerisa Riedl, Olga Barmina, Benjamin J. Liebeskind, Li Zhao, David Begun and Artyom Kopp | Summary: Changes in gene expression are a key driver of phenotypic evolution, leading to a persistent interest in the evolution of transcriptomes. Traditionally, gene expression is modeled […]


Continue.. Quantifying transcriptome turnover on phylogenies by modeling gene expression as a binary trait

Long-Term Effects of Early Adolescent Second-Generation Antipsychotic Exposure on Body Weight, Caloric Intake, and Metabolism-Associated Gene Expression

Kavli Affiliate: Michael W. Young | Authors: Paul Soto, Michael E Young, Serena Nguyen, Megan Federoff, Mia M Goodson, Christopher D Morrison, Heidi Batdorf, Susan Burke and Jason Collier | Summary: The use of second-generation antipsychotic (SGA) medications in pediatric patients raises concerns about potential long-term adverse outcomes. The current study evaluated the long-term effects […]


Continue.. Long-Term Effects of Early Adolescent Second-Generation Antipsychotic Exposure on Body Weight, Caloric Intake, and Metabolism-Associated Gene Expression

Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine

Kavli Affiliate: Charles M. Rice | Authors: Samantha G Muccilli, Bejamin Schwarz, Forrest Jessop, Jeffrey G. Shannon, Eric Bohrnsen, Byron Shue, Seon-Hui Hong, Thomas Hsu, Alison W. Ashbrook, Joseph W. Guarnieri, Justin Lack, Douglas C. Wallace, Catharine M. Bosio, Margaret R. MacDonald, Charles M Rice, Jonathan W Yewdell and Sonja M. Best | Summary: The […]


Continue.. Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine

Spontaneously regenerative corticospinal neurons in mice

Kavli Affiliate: Nathaniel Heintz | Authors: Benjamin W Fait, Bianca Cotto, Tatsuya C Murakami, Michael Hagemann-Jensen, Huiqing Zhan, Corinne Freivald, Isadora Turbek, Yuan Gao, Zizhen Yao, Sharon W Way, Hongkui Zeng, Bosiljka Tasic, Oswald Steward, Nathaniel Heintz and Eric F Schmidt | Summary: The spinal cord receives inputs from the cortex via corticospinal neurons (CSNs). […]


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Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division

Kavli Affiliate: Li Zhao | Authors: Nathan Palmer, S. Zakiah A. Talib, Jin Rong Ow, Tommaso Tabaglio, Christine M.F. Goh, Li Na Zhao, Ernesto Guccione, Kui Liu and Philipp Kaldis | Summary: In most mammals, the cell cycle kinase; cyclin-dependent kinase 2 (CDK2) is expressed as two major isoforms due to the inclusion or exclusion […]


Continue.. Differential splice isoforms of mouse CDK2 play functionally redundant roles during mitotic and meiotic division

HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer

Kavli Affiliate: Li Zhao | Authors: Daniel Ranti, Haocheng Yu, Yuanshuo Wang, Christine Bieber, Trine Strandgaard, Berengere Salome, Sean Houghton, Junbum Kim, Hiranmayi Ravichandran, Iyinyeoluwa Okulate, Elliot Merritt, Sunjoo Bang, Alexandros Demetriou, Zhao Li, Sia Viborg Lindskrog, Dan Fu Ruan, Jorge Daza, Richa Rai, Everardo Hegewisch-Solloa, Emily Mace, Ruben Fernandez-Rodriguez, Sudeh Izadmehr, Glenn Doherty, Adam […]


Continue.. HLA-E and NKG2A Mediate Resistance to M. bovis BCG Immunotherapy in Non-Muscle-Invasive Bladder Cancer

Estrus-Tracking Cortical Neurons Integrate Social cues and Reproductive states to Adaptively Control Sexually Dimorphic Sociosexual Behaviors

Kavli Affiliate: Nathaniel Heintz | Authors: Yuping Wang, Xinli Song, Xiangmao Chen, Ying Zhou, Jihao Ma, Fang Zhang, Liqiang Wei, Guoxu Qi, Nakul Yadav, Benjie Miao, Yiming Yan, Guohua Yuan, Da Mi, Priyamvada Rajasethupathy, Ines Ibanez-Tallon, Xiaoxuan Jia, Nathaniel Heintz and Kun Li | Summary: Female sociosexual behaviors, essential for survival and reproduction, are adaptively […]


Continue.. Estrus-Tracking Cortical Neurons Integrate Social cues and Reproductive states to Adaptively Control Sexually Dimorphic Sociosexual Behaviors

Brain Charts for the Rhesus Macaque Lifespan

Kavli Affiliate: Winrich Freiwald | Authors: Samuel Alldritt, Julian S.B. Ramirez, Reinder Vos de Wael, Richard Bethlehem, Jakob Seidlitz, Zexi Wang, Karl-Heinz Nenning, Nathalia B. Esper, Jonathan Smallwood, Alexandre R. Franco, Kyoungseob Byeon, Aaron Alexander-Bloch, Adam Messinger, Aihua Chen, Alexander Thiele, Alison R. Weiss, Amir Shmuel, Andrew Fox, Anita Tusche, Ansgar M. Brambrink, Arnaud Falchier, […]


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