C. elegans CED-3 caspase promotes non-apoptotic linker cell dismantling but not death onset

Kavli Affiliate: Shai Shaham | Authors: Olya Yarychkivska, Lena M Kutscher, Betty Ortiz Bido, Juliana Kagan, Yoon A Kim, Dana Mamriev, Yun Lu, Elli Puscher, Wolfgang Keil, Sarit Larisch and Shai Shaham | Summary: dismantling of the C. elegans linker cell, which undergoes non-apoptotic morphologically-conserved cell death characterized by nuclear envelope crenellations and cell splitting. […]


Continue.. C. elegans CED-3 caspase promotes non-apoptotic linker cell dismantling but not death onset

Neural representation of action grammar structure in primate frontal cortex

Kavli Affiliate: Stefano Fusi | Authors: Ramon Nogueira, Saleh Esteki, Stefano Fusi and Roozbeh Kiani | Summary: Humans and other animals can solve new problems, even on the first attempt. This capacity to generate novel problem-solving behavior has been hypothesized to depend on brain mechanisms for recombining units of knowledge using systems of procedural rules, […]


Continue.. Neural representation of action grammar structure in primate frontal cortex

Cell type-specific proximity labeling of organ secretomes reveals energy balance-dependent proteomic remodeling.

Kavli Affiliate: Jeffrey M. Friedman and Ekaterina V. Vinogradova | Authors: Kaja Plucinska, Charlotte R Wayne, Henry Sanford, Boby Mathew, Nathalie Ropek, Stephanie M Adaniya, Corey Model, Nicolas Gomez-Banoy, Ksenia Morozova, Xiongwen Cao, Jeffrey M. Friedman, Ken H. Loh, Paul Cohen and Ekaterina V Vinogradova | Summary: Intercellular communication is critical for maintaining organismal metabolic […]


Continue.. Cell type-specific proximity labeling of organ secretomes reveals energy balance-dependent proteomic remodeling.

A commensally regulated immune rheostat fine-tunes skin barrier fitness

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Elaine Fuchs | Authors: Anita Gola, Rohith Srinivas, Elias G. Rodig, Marina Schernthanner, Merve Deniz Abdusselamoglu, Matthew T. Tierney, Natalie J. Alexander, Kevin A.U. Gonzales, Sairaj M. Sajjath, Luis F. Soto-Ugaldi, Alain R. Bonny and Elaine Fuchs | Summary: At […]


Continue.. A commensally regulated immune rheostat fine-tunes skin barrier fitness

C. elegans E3 ubiquitin ligase EBAX-1 promotes non-apoptotic linker cell-type death through target-directed miRNA degradation

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Shai Shaham | Authors: Lauren B Horowitz, Olya Yarychkivska, Yun Lu and Shai Shaham | Summary: Programmed cell death is essential for animal development and homeostasis, and its disruption accompanies many human disorders. Linker cell-type death (LCD) is a morphologically […]


Continue.. C. elegans E3 ubiquitin ligase EBAX-1 promotes non-apoptotic linker cell-type death through target-directed miRNA degradation

Biological signatures of history: Examination of composite biomes and Y chromosome analysis from da Vinci-associated cultural artifacts

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Thomas P. Sakmar | Authors: Harinder Singh, Seesandra V Rajagopala, Rebecca Hart, Pille Hallast, Mark Loftus, Rosana Wiscovitch-Russo, Cody R. K. Conrad, David S Thaler, Guadalupe Piñar, Karina C Åberg, Rosella Lorenzi, Jose A Lorente, Jesse H Ausubel, Thomas P […]


Continue.. Biological signatures of history: Examination of composite biomes and Y chromosome analysis from da Vinci-associated cultural artifacts

Radial-glia-to-astrocyte trans-differentiation and astrocyte transcriptional convergence are coordinated by CEH-43/DLX in C. elegans

Kavli Affiliate: Shai Shaham | Authors: Simin Liu, Kenneth Bradley, Jinghong J. Tang, Yoon A. Kim, Ana Milosevic and Shai Shaham | Summary: Mammalian radial glia can remodel to become astrocytes, which acquire common transcriptional states despite spatially and lineally distinct origins. To uncover molecular programs driving convergent radial-glia-to-astrocyte transformation, we investigated development of C. […]


Continue.. Radial-glia-to-astrocyte trans-differentiation and astrocyte transcriptional convergence are coordinated by CEH-43/DLX in C. elegans

Neural representation of action symbols in primate frontal cortex

Kavli Affiliate: Winrich Freiwald | Authors: Lucas Y Tian, Kedar Garzón Gupta, Daniel J. Hanuska, Adam G Rouse, Mark AG Eldridge, Marc H Schieber, Xiao-Jing Wang, Joshua B Tenenbaum and Winrich A Freiwald | Summary: A hallmark of intelligence is proficiency in solving new problems, including those that differ dramatically from problems seen before. Problem-solving, […]


Continue.. Neural representation of action symbols in primate frontal cortex

High-Fidelity Tuning of Olfactory Mixture Distances in the Perceptual Space of Smell Through a Community Effort

Kavli Affiliate: Leslie B. Vosshall | Authors: Vahid Satarifard, Laura Sisson, Yikun Han, Pedro Ilidio, Matej Hladis, Maxence Lalis, Xuebo Song, Wenjie Yin, Aharon Ravia, CiCi Xingyu Zheng, Gaia Andreoletti, Jake Albrecht, Robert Pellegrino, Zehua Wang, Stephen Yang, Robbe D’hondt, Achilleas Ghinis, Jasper de Boer, Felipe Kenji Nakano, Alireza Gharahighehi, DREAM Olfactory Mixtures Prediction Consortium, […]


Continue.. High-Fidelity Tuning of Olfactory Mixture Distances in the Perceptual Space of Smell Through a Community Effort

A cross-species spatial transcriptomic atlas of the human and non-human primate basal ganglia

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Winrich Freiwald | Authors: Nelson J. Johansen, Yuanyuan Fu, Matthew Schmitz, Alma Dubuc, Niklas Kempynck, Morgan Wirthlin, Aaron D. Garcia, Madeleine Hewitt, Meghan A. Turner, Stephanie C. Seeman, Brian Long, Xiao-Ping Liu, Shu Dan, Michael DeBerardine, Inkar Kapen, Anna Marie […]


Continue.. A cross-species spatial transcriptomic atlas of the human and non-human primate basal ganglia