The emergence of human gastrulation upon in vitro attachment

Kavli Affiliate: Ali H. Brivanlou | Authors: Riccardo De Santis, Eleni Rice, Gist Croft, Min Yang, Edwin A. Rosado-Olivieri and Ali H. Brivanlou | Summary: While studied extensively in model systems, human gastrulation remains obscure. This process starts upon blastocyst implantation into the uterine wall, which is assumed to occur after 14 days post-fertilization. The […]


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Towards the biogeography of butyrate-producing bacteria

Kavli Affiliate: Robert Edwards | Authors: Joel E Brame, Craig Liddicoat, Catherine A Abbott, Robert A Edwards, Jake M Robinson, Nicolas E Gauthier and Martin F Breed | Summary: Butyrate-producing bacteria are found in many ecosystems and organisms, including humans, and are vital to ecosystem functionality and human health. These bacteria ferment organic matter, producing […]


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Invariant neural dynamics drive commands to control different movements

Kavli Affiliate: Rui Costa | Authors: Vivek Ravindra Athalye, Preeya Khanna, Suraj Gowda, Amy L Orsborn, Rui M Costa and Jose M Carmena | Summary: It has been proposed that the nervous system has the capacity to generate a wide variety of movements because it re-uses some invariant code. Previous work has identified that dynamics […]


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Social experiences shape song preference learning independent of developmental exposure to song

Kavli Affiliate: Sarah Woolley | Authors: Erin Mckenzie Wall and Sarah Cushing Woolley | Summary: Communication governs the formation and maintenance of social relationships. The interpretation of communication signals depends not only on the signal’s content, but also on a receiver’s individual experience. Experiences throughout life may interact to affect behavioral plasticity, such that a […]


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Allosteric regulation of TRPV1 by the inflammatory lipid, LPA

Kavli Affiliate: Yifan Cheng | Authors: William Randall Arnold, David Julius and Yifan Cheng | Summary: Transient Receptor Potential Vanilloid 1 (TRPV1) is a tetrameric cation channel expressed in primary afferent neurons, where it contributes to thermosensation and nociception. TRPV1 is a polymodal signal integrator that responds not only to heat, but also to inflammatory […]


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Reward contingency gates selective cholinergic suppression of amygdala neurons

Kavli Affiliate: Kay Tye | Authors: Eyal Y. Kimchi, Anthony Burgos-Robles, Gillian A Matthews, Tatenda Chakoma, Makenzie Patarino, Javier C Weddington, Cody A Siciliano, Wannan Yang, Shaun Foutch, Renee Simons, Ming-fai Fong, miao jing, Yulong Li, Daniel B Polley and Kay M. Tye | Summary: Basal forebrain cholinergic neurons modulate how organisms process and respond […]


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Fiberoptic Probe For Hemodynamic Spectroscopy in Freely Moving Mice Shows Cerebrovascular Dysregulation In Alzheimers and Glioma Models

Kavli Affiliate: Sidney Strickland | Authors: Daniel S. Gareau, Matija Snuderl, Cheddhi Thomas, Nermin Sumru Bayin, Dimitris Placantonakis, Julia Zou, Anna Yaroslavsky, Michael P. Dietz, Steven L. Jacques, Sidney Strickland, James G. Krueger and Hyung Jin Ahn | Summary: Significance Cerebral vascular reactivity is critical parameters of brain homeostasis in health and disease, but the […]


Continue.. Fiberoptic Probe For Hemodynamic Spectroscopy in Freely Moving Mice Shows Cerebrovascular Dysregulation In Alzheimers and Glioma Models

Foxj1 controls olfactory ciliogenesis and differentiation program of the olfactory sensory neurons

Kavli Affiliate: Emre Yaksi | Authors: Dheeraj Rayamajhi, Mert Ege, Kirill Ukhanov, Christa Ringers, Yiliu Zhang, Inyoung Jeong, Percival P D’Gama, Summer Shijia Li, Mehmet Ilyas Cosacak, Caghan Kizil, Hae-Chul Park, Emre Yaksi, Jeffrey R Martens, Steven L Brody, Nathalie Jurisch-Yaksi and Sudipto Roy | Summary: In vertebrates, olfactory receptors localize on multiple cilia elaborated […]


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Dopamine signaling regulates predator-driven changes in Caenorhabditis elegans egg laying behavior

Kavli Affiliate: Sreekanth Chalasani | Authors: Amy Pribadi, Michael A Rieger, Kaila Rosales, Kirthi C Reddy and Sreekanth H Chalasani | Summary: Prey respond to predators by altering their behavior to optimize their own fitness and survival. Specifically, prey are known to avoid predator-occupied territories to reduce their risk of harm or injury to themselves […]


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Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods

Kavli Affiliate: Edward Chang | Authors: Alejandro Omar Blenkmann, Sabine Liliana Leske, Anais Llorens, Jack J Lin, Edward Chang, Peter Brunner, Gerwin Schalk, Jugoslav Ivanovic, Pal Gunnar Larsson, Robert Thomas Knight, Tor Endestad and Anne-Kristin Solbakk | Summary: Precise electrode localization is important for maximizing the utility of intracranial EEG data. Electrodes are typically localized […]


Continue.. Anatomical registration of intracranial electrodes. Robust model-based localization and deformable smooth brain-shift compensation methods