Neuroscience – Page 82 – Kavli Institute Pre-Print Publications

BrainLine: An Open Pipeline for Connectivity Analysis of Heterogeneous Whole-Brain Fluorescence Volumes

Posted by klaurent March 1, 2023March 14, 2023Hopkins

Kavli Affiliate: Michael Miller, Joshua Vogelstein | Authors: Thomas Athey, Matthew Wright, Marija Pavlovic, Vikram Chandrashekhar, Karl Deisseroth, Michael Miller and Joshua Vogelstein | Summary: Whole-brain fluorescence images require several stages of computational processing to fully reveal the neuron morphology and connectivity information they contain. However, these computational tools are rarely part of an integrated […]

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Inhibitory control of speech production in the human premotor frontal cortex

Posted by klaurent March 1, 2023March 14, 2023UCSF

Kavli Affiliate: Edward Chang | Authors: Lingyun Zhao, Alexander B. Silva, Garret L. Kurteff and Edward F. Chang | Summary: Natural speech is full of starts and stops. Here, we studied the neural mechanisms that underlie the inhibitory control of speech, specifically the ability to stop speaking on demand. We recorded direct cortical activity while […]

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White matter and literacy: a dynamic system in flux

Posted by klaurent March 1, 2023March 14, 2023UCSD / Salk

Kavli Affiliate: Terry Jernigan, Timothy Brown | Authors: Ethan Roy, Adam Richie-Halford, John Kruper, Manjari Narayan, David Bloom, Pierre Nedelec, Leo P. Sugrue, Andreas Rauschecker, Timothy T. Brown, Terry L. Jernigan, Bruce D. McCandliss, Ariel Rokem and Jason D. Yeatman | Summary: Cross-sectional studies have linked differences in white matter tissue properties to reading skills. […]

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A frontosensory circuit for visual context processing is synchronous in the theta/alpha band

Posted by klaurent February 25, 2023March 7, 2023Columbia

Kavli Affiliate: Darcy Peterka | Authors: Georgia Bastos, Jacob T Holmes, Jordan M Ross, Anna M Rader, Connor G Gallimore, Darcy S Peterka and Jordan P Hamm | Summary: Visual processing is strongly influenced by context. Stimuli that deviate from contextual regularities elicit augmented responses in primary visual cortex (V1). These heightened responses, known as […]

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Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer’s Knock-in Mice Require Cellular Prion Protein

Posted by klaurent February 23, 2023March 7, 2023Yale

Kavli Affiliate: Stephen Strittmatter | Authors: Austin Stoner, Li Fu, LaShae Nicholson, Chao Zheng, Takuya Toyonaga, Joshua Spurrier, Will Laird, Zhengxin Cai and Stephen M. Strittmatter | Summary: Background Cellular prion protein (PrPC) is a high-affinity cell-surface receptor for Amyloid-β oligomers (Aßo). In certain overexpression models of Alzheimer’s Disease (AD), pharmacology and genetics demonstrate its […]

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Phased nanopore assembly with Shasta and modular graph phasing with GFAse

Posted by klaurent February 22, 2023March 7, 2023Columbia

Kavli Affiliate: Richard Axel | Authors: Ryan Lorig-Roach, Melissa Meredith, Jean Monlong, Miten Jain, Hugh Olsen, Brandy McNulty, David Porubsky, Tessa G. Montague, Julian Lucas, Chris Condon, Jordan Eizenga, Sissel Juul, Sean McKenzie, Sara Simmonds, Jimin Park, Mobin Asri, Sergey Koren, Evan Eichler, Richard Axel, Bruce Martin, Paolo Carnevali, Karen Miga and Benedict Paten | […]

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Early retinal deprivation crossmodally alters nascent subplate circuits and activity in the auditory cortex during the precritical period

Posted by klaurent February 21, 2023March 7, 2023Hopkins

Kavli Affiliate: Patrick Kanold | Authors: Didhiti Mukherjee, Binghan Xue, Chih-Ting Chen, Minzi Chang, Joseph P-Y. Kao and Patrick O. Kanold | Summary: Sensory perturbation in one modality results in adaptive reorganization of neural pathways within the spared modalities, a phenomenon known as “crossmodal plasticity”, which has been examined during or after the classic ‘critical […]

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Prdm16 and Vcam1 regulate the postnatal disappearance of embryonic radial glia and the ending of cortical neurogenesis

Posted by klaurent February 16, 2023March 7, 2023UCSF

Kavli Affiliate: Arturo Alvarez-Buylla | Authors: Jiwen Li, Marlesa I. Godoy, Alice J. Zhang, Graciel Diamante, In Sook Ahn, Arantxa Cebrian-Silla, Arturo Alvarez-Buylla, Xia Yang, Bennett G. Novitch and Ye Zhang | Summary: Embryonic neural stem cells (NSCs, i.e., radial glia) in the ventricular-subventricular zone (V-SVZ) generate the majority of neurons and glia in the […]

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Spatial heterogeneity in biofilm metabolism elicited by local control of phenazine methylation

Posted by klaurent February 16, 2023March 7, 2023Columbia

Kavli Affiliate: Wei Min | Authors: Christopher R. Evans, Marina K. Smiley, Sean Asahara Thio, Mian Wei, Alexa Price-Whelan, Wei Min and Lars E.P. Dietrich | Summary: Within biofilms, gradients of electron acceptors such as oxygen stimulate the formation of physiological subpopulations. This heterogeneity can enable cross-feeding and promote drug resilience, features of the multicellular […]

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Alteration of functional connectivity in the cortex and major brain networks of non-human primates following focused ultrasound exposure

Posted by klaurent February 16, 2023February 28, 2023Columbia

Kavli Affiliate: Vincent Ferrera | Authors: Dong Liu, Fabian A Munoz Silva, Soroosh Sanatkhani, Antonios Pouliopoulos, Elisa Konofagou, Jack Grinband and Vincent P. Ferrera | Summary: Focused ultrasound (FUS) is a non-invasive neuromodulation technology that is being investigated for potential treatment of neurological and psychiatric disorders. Focused ultrasound combined with microbubbles can temporarily open the […]

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