Kavli Affiliate: Costa, Rui | Authors: Joseph Pemberton, Paul Chadderton and Rui Ponte Costa | Summary: Abstract To drive behavior, the cortex must bridge sensory cues with future outcomes. However, the principles by which cortical networks learn such sensory-behavioural transformations remain largely elusive. Here, we posit that the cerebellum assumes a crucial role in driving […]
Kavli Affiliate: Leslie B. Vosshall | Authors: Takeshi Morita, Nia G Lyn, Ricarda K von Heynitz, Olivia V Goldman, Trevor R Sorrells, Matthew DeGennaro, Benjamin J Matthews, Leah Houri-Zeevi and Leslie B Vosshall | Summary: Sensory compensation is a process that allows individuals with a loss of one sense, for instance hearing or vision, to […]
Kavli Affiliate: Zachary Knight & Jeffrey M. Friedman | Authors: Christin Kosse, Jessica Ivanov, Zachary Knight, Kyle Pellegrino and Jeffrey Friedman | Summary: The brain processes an array of stimuli enabling the selection of an appropriate behavioural response but the underlying circuitry linking inputs to outputs is unknown. Here we delineate a subcortical circuit in […]
Kavli Affiliate: V. S. Ramachandran | Authors: Vysakh Ramachandran and Davit A Potoyan | Summary: Conformational dynamics plays crucial roles in RNA functions about sensing and responding to environmental signals. The liquid-liquid phase separation of RNAs and the formation of stress granules partly relies on RNA’s conformational plasticity and its ability to engage in multivalent […]
Kavli Affiliate: Deanna J. Greene | Authors: Carolina Badke D’Andrea, Timoth O Laumann, Dillan J Newbold, Steven M Nelson, Ashley N Nielsen, Roselyne Chauvin, Scott Marek, Deanna J. Greene, Nico U F Dosenbach and Evan M Gordon | Summary: HThe Cingulo-Opercular network (CON) is an executive network of the human brain that regulates actions. CON […]
Kavli Affiliate: Timothy A. Ryan & Pietro De Camilli | Authors: Talex Kokotos, Aldana Antoniazzi, Santiago Unda, Myung Soo Kokotos, Daehun Park, David Eliezer, Michael Kaplitt, Pietro De Camilli and Timothy Ryan | Summary: Phosphoglycerate kinase 1 (PGK1), the first ATP producing glycolytic enzyme, has emerged as a therapeutic target for Parkinson’s Disease (PD), since […]
Kavli Affiliate: Daniel Mucida | Authors: Gregory P. Donaldson, Gabriella L. Reis, Marwa Saad, Izabela Mamede, Guo Chen, Nicole L. DelGaudio, Dayu Zhang, Begum Aydin, Caroline E. Harrer, Tiago B.R. Castro, Sergei Grivennikov, Bernardo S. Reis, Beth M. Stadtmueller, Gabriel D. Victora and Daniel Mucida | Summary: Immunoglobulin A (IgA) is the most abundant antibody […]
Kavli Affiliate: Xin Duan | Authors: Axel Guskjolen, Jagroop Dhaliwal, Juan de la Parra, Jonathan R Epp, Sangyoon Ko, Erin Chahley, Mitch de Snoo, Michela Solari, Prabdeep Panesar, Jason Scott Snyder, Xin Duan, Joshua Sanes, Sheena Josselyn and Paul Frankland | Summary: Post-training increases in hippocampal neurogenesis are associated with forgetting of hippocampus-dependent memories in […]
Kavli Affiliate: Arturo Alvarez-Buylla | Authors: Yajun Xie, Christopher M Reid, Alejandro A Granados, Miguel Turrero Garcia, Fiona Dale-Huang, Sarah M Hanson, Walter R Mancia Leon, Jonathan Liu, Manal A Adam, Olivia Mosto, Angela Oliveira Pisco, Arturo Alvarez-Buylla and Corey C Harwell | Summary: Astrocyte specification during development is influenced by both intrinsic and extrinsic […]
Kavli Affiliate: Cory Miller | Authors: Dori Grijseels, Daniella Fairbank and Cory Miller | Summary: Vocal turn-taking has been described in a diversity of species. Yet a model that captures the various processes underlying this social behavior across species has not been developed. To this end, here we recorded a large and diverse dataset of […]