Neuroscience – Page 32 – Kavli Institute Pre-Print Publications

Disparate demographic impacts of the Roman Colonization and the Migration Period in the Iberian Peninsula

Posted by dbos September 23, 2024October 7, 2024UCSD / Salk

Kavli Affiliate: Jose Ricardo Suarez | Authors: Pablo Carrion, Inigo Olalde, Juan Manuel Jimenez-Arenas, Neus Coromina, David Vivo, Josep Maria Verges, Ana Costa, Daniel Botella, Macarena Bustamante-Alvarez, Javier Heras-Mora, Ricardo Ortega-Ruiz, Celia Chaves, Maite Iris Garcia-Collado, Juan Quiros-Castillo, Jordi Roig, Jose Suarez-Padilla, Ildelfonso Navarro-Luengo, Miguel Angel Cuadrado, Isidro Aguilera, Jordi Morera, Raul Catalan, Maria Luisa […]

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A feedforward mechanism for human-like contour integration

Posted by dbos September 23, 2024October 7, 2024Harvard

Kavli Affiliate: George A. Alvarez | Authors: Fenil R. Doshi, Talia Konkle and George A. Alvarez | Summary: Summary: Deep neural network models provide a powerful experimental platform for exploring core mechanisms underlying human visual perception, such as perceptual grouping and contour integration — the process of linking local edge elements to arrive at a […]

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Targeting the host transcription factor HSF1 prevents human cytomegalovirus replication in vitro and in vivo

Posted by dbos September 23, 2024October 7, 2024Hopkins

Kavli Affiliate: Michael Miller | Authors: Juthi Biswas, Dilruba Akter, Michael J Miller, Dennis J Thiele, Eain A. Murphy, Christine O’Connor, Jennifer F Moffat and Gary Chan | Summary: Summary: FDA-approved antivirals against HCMV have several limitations, including only targeting the later stages of the viral replication cycle, adverse side effects, and the emergence of […]

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Hippocampal representations of alternative possibilities are flexibly generated to meet cognitive demands

Posted by dbos September 23, 2024October 7, 2024UCSF

Kavli Affiliate: Joshua Berke and Loren Frank | Authors: Alison E. Comrie, Emily J. Monroe, Ari E. Kahn, Eric L. Denovellis, Abhilasha Joshi, Jennifer A. Guidera, Timothy A. Krausz, Joshua D. Berke, Nathaniel D. Daw and Loren M. Frank | Summary: Summary: The cognitive ability to go beyond the present to consider alternative possibilities, including […]

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High-Resolution Laminar Identification in Macaque Primary Visual Cortex Using Neuropixels Probes

Posted by dbos September 22, 2024September 30, 2024UCSD / Salk

Kavli Affiliate: Edward Callaway | Authors: Li Alex Zhang, Peichao Li and Edward M. Callaway | Summary: Summary: Laminar electrode arrays allow simultaneous recording of activity of many cortical neurons and assignment to layers using current source density (CSD) analyses. Electrode arrays with 100-micron contact spacing have been used to estimate borders between layer 4 […]

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The HIV-1 Nuclear Export Complex Reveals the Role of RNA in Crm1 Cargo Recognition

Posted by dbos September 22, 2024September 30, 2024UCSF

Kavli Affiliate: Keri Martinowich | Authors: Amber M Smith, Yang Li, Arianna Velarde, Yifan Cheng and Alan D. Frankel | Summary: Summary: Crm1 is a highly conserved nuclear exportin that transports >1000 human proteins including ribonucleoprotein (RNP) complexes. The interface between Crm1 and RNP cargos is unknown. The HIV regulatory protein, Rev, was one of […]

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Transcriptomic characterization of human lateral septum neurons reveals conserved and divergent marker genes across species

Posted by dbos September 22, 2024September 30, 2024Hopkins

Kavli Affiliate: Keri Martinowich | Authors: Robert A Phillips III, Seyun Oh, Svitlana V Bach, Yufeng Du, Ryan A Miller, Joel E Kleinman, Thomas M Hyde, Stephanie C Hicks, Stephanie Cerceo Page and Keri Martinowich | Summary: The lateral septum (LS) is a midline, subcortical structure, which regulates social behaviors that are frequently impaired in […]

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Mobius Assembly for Plant Systems highlights promoter-coding sequence terminator interaction in gene regulation

Posted by dbos September 21, 2024September 30, 2024Hopkins

Kavli Affiliate: Andreas Andreou | Authors: Elif Gediz Kocaoglan, Andreas Andreou, Jessica Nirkko, Marisol Ochoa-Villarreal, Gary Loake and Naomi Nakayama | Summary: Plants are the primary biological platforms for producing food, energy, and materials in agriculture; however, they remain a minor player in the recent synthetic biology-driven transformation in bioproduction. Molecular tools and technologies for […]

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Altered development and network connectivity in a human neuronal model of 15q11.2 deletion-related neurodevelopmental disorders

Posted by dbos September 20, 2024September 30, 2024Hopkins

Kavli Affiliate: Dwight Bergles | Authors: Christa Whelan Habela, Shiyu Liu, Arens Taga, Raha Dastgheyb, Norman Haughey, Dwight E Bergles, Hongjun Song, Guo-Li Ming and Nicholas J. Maragakis | Summary: The chromosome 15q11.2 locus is deleted in 1.5% of patients with genetic epilepsy and confers a risk for intellectual disability and schizophrenia. Individuals with this […]

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Lateral prefrontal cortex controls interplay between working memory and actions

Posted by dbos September 18, 2024September 30, 2024UCSD / Salk

Kavli Affiliate: Anastasia Kiyonaga | Authors: Anastasia Kiyonaga, Jacob Miller and Mark D’Esposito | Summary: Humans must often keep multiple task goals in mind, at different levels of priority and immediacy, while also interacting with the environment. We might need to remember information for an upcoming task while engaged in more immediate actions. Consequently, actively […]

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