Kavli Affiliate: Mounya Elhilali/p> | Authors: Kai Lu, Kelsey Dutta, Ali Mohammed, Mounya Elhilali and Shihab Shamma | Summary: Binding the attributes of a sensory source is necessary to perceive it as a unified entity, one that can be attended to and extracted from its surrounding scene. In auditory perception, this is the essence of […]
Kavli Affiliate: Jeremy Willsey/p> | Authors: Kate E McCluskey, Katherine M Stovell, Karen Law, Elina Kostyanovskaya, James Schmidt, Cameron RT Exner, Jeanselle Dea, Elise Brimble, Matthew W State, A Jeremy Willsey and Helen Rankin Willsey | Summary: The comorbidity of autism spectrum disorders and severe gastrointestinal symptoms is well-established, yet the molecular underpinnings remain unknown. […]
Kavli Affiliate: Flora Vaccarino | Authors: Soraya Scuderi, Tae-Yun Kang, Alexandre Jourdon, Liang Yang, Feinan Wu, Alex Nelson, George M. Anderson, Jessica Mariani, VIVEKANANDA SARANGI, Alexej Abyzov, Andre Levchenko and Flora M. Vaccarino | Summary: The repertory of neurons generated by progenitor cells depends on their location along antero-posterior and dorso-ventral axes of the neural […]
Kavli Affiliate: Timothy A. Ryan | Authors: Kirsten Bredvik and Timothy A Ryan | Summary: Inhibitory neurons shape the brain’s computational landscape and rely on different cellular architectures and intrinsic properties than excitatory neurons. Maintenance of the overall balance of excitatory (E) versus inhibitory (I) drive is essential, as disruptions can lead to neuropathological conditions, […]
Kavli Affiliate: Liam Paninski | Authors: Pojeong Park, J. David Wong-Campos, Daniel Itkis, Byung Hun Lee, Yitong Qi, Hunter C. Davis, Benjamin Antin, Amol Praveen Pasarkar, Jonathan B. Grimm, Sarah E. Plutkis, Katie L. Holland, Liam Paninski, Luke Lavis and Adam Ezra Cohen | Summary: Dendrites on neurons support nonlinear electrical excitations, but the computational […]
Kavli Affiliate: Edvard Moser and May-Britt Moser | Authors: Abraham Z. Vollan, Richard J. Gardner, May-Britt Moser and Edvard I. Moser | Summary: Place cells in the hippocampus and grid cells in the entorhinal cortex are elements of a neural map of self- position. To benefit navigation, this representation must be dynamically related to surrounding […]
Kavli Affiliate: Kristina Nielsen Loyal Goff | Authors: Soraia Barao, Yijun Xu, Rachel Vistein, Loyal Goff, Kristina Nielsen, Byoung-Il Bae, Richard S. Smith, Christopher A Walsh, Genevieve Stein O Brien and Ulrich Muller | Summary: The mammalian neocortex differs vastly in size and complexity between mammalian species, yet the mechanisms that lead to an increase […]
Kavli Affiliate: Sreekanth Chalasani | Authors: Kathleen T Quach, Gillian A Hughes and Sreekanth H Chalasani | Summary: Prey must balance the need to avoid predators with the need to feed, a dilemma central to prey refuge theory. Additionally, prey must also assess predatory imminence, or how close predator threats are in space and time. […]
Kavli Affiliate: Jean Fan | Authors: Jude Marvin Phillip, Pratik Kamat, Nico Macaluso, Chanhong Min, Yukang Li, Anshika Agrawal, Aaron Winston, Lauren Pan, Bartholomew Marvin Starich, Teasia Stewert, Pei-Hsun Wu, Jean Fan and Jeremy Walston | Summary: Cellular senescence is an established driver of aging, exhibiting context-dependent phenotypes across multiple biological length-scales. Despite its mechanistic […]
Kavli Affiliate: Jin Kang | Authors: Alexandra Nelson and Anatol Kreitzer | Summary: Parkinson’s disease (PD) is characterized by the death of substantia nigra (SNc) dopamine (DA) neurons, but the pathophysiological mechanisms that precede and drive their death remain unknown. The activity of DA neurons is likely altered in PD, but we understand little about […]