Kavli Affiliate: Michael Shadlen | Authors: Naomi N Odean, Mehdi Sanayei and Michael N Shadlen | Summary: Abstract To form a perceptual decision the brain must acquire samples of evidence from the environment and incorporate them in computations that mediate choice behavior. While much is known about the neural circuits that process sensory information and […]
Kavli Affiliate: Marcelo Mattar | Authors: Flora Bouchacourt, Sina Tafazoli, Marcelo Gomes Mattar, Timothy J Buschman and Nathaniel Douglass Daw | Summary: Abstract To adapt to a changing world, we must be able to switch between rules already learned and, at other times, learn rules anew. Often we must do both at the same time, […]
Kavli Affiliate: David Rowitch | Authors: Tanay Ghosh, Rafael G Almeida, Chao Zhao, Abdelkrim Mannioui, Elodie Martin, Alex Fleet, Ginez Gonzalez M, David H Rowitch, Katherine Stott, Ian Adams, Bernard Zalc, Nick Goldman, David A Lyons and Robin JM Franklin | Summary: Abstract Myelin, the insulating sheath that surrounds neuronal axons, is produced by oligodendrocytes […]
Kavli Affiliate: John Reynolds | Authors: Sachira Denagamage, Mitchell P. Morton, John H. Reynolds, Monika P. Jadi and Anirvan S. Nandy | Summary: Saccades are a ubiquitous and crucial component of our visual system, allowing for the efficient deployment of the fovea and its accompanying neural resources. Initiation of a saccade is known to cause […]
Kavli Affiliate: Tejal Desai | Authors: Joel A Finbloom, Preethi Raghavan, Michael Kwon, Bhushan N Kharbikar, Michelle A Yu and Tejal A Desai | Summary: Abstract New approaches are needed to treat bacterial biofilm infections, particularly those of Pseudomonas aeruginosa (PA), which have high rates of antimicrobial resistance and are commonly found in chronic wound […]
Kavli Affiliate: Li Zhao | Authors: Evan Witt, Christopher B Langer, Nicolas Svetec and Li Zhao | Summary: Abstract Aging is a complex biological process that is accompanied by changes in gene expression and mutational load. In many species, including humans, older fathers pass on more paternally-derived de novo mutations; however, the cellular basis and […]
Kavli Affiliate: Edward Chang | Authors: DANQING ZHU, David H Brookes, Akosua Busia, Ana Carneiro, Clara Fannjiang, Galina Popova, David Shin, Edward F Chang, Tomasz J. Nowakowski, Jennifer Listgarten and David V Schaffer | Summary: Abstract Adeno-associated viruses (AAVs) hold tremendous promise as delivery vectors for clinical gene therapy, but they need improvement. AAVs with […]
Kavli Affiliate: John Reynolds | Authors: Kandarp Dave, Donna B Stolz, Venugopal R Venna, Victoria A. Quaicoe, Michael E Maniskas, Michael John Reynolds, Riyan Babidhan, Duncan X Dobbins, Maura N. Farinelli, Abigail Sullivan, Tarun N. Bhatia, Hannah Yankello, Rohan Reddy, Younsoo Bae, Rehana K Leak, Sruti Shiva, Louise D McCullough and Devika Soundara Manickam | […]
Kavli Affiliate: John Reynolds | Authors: Kandarp Dave, Donna B Stolz, Michael John Reynolds, Riyan Babidhan, Duncan X Dobbins, Tarun N. Bhatia, Hannah Yankello, Rohan Reddy, Younsoo Bae, Rehana K Leak, Sruti Shiva and Devika Soundara Manickam | Summary: Ischemic stroke causes brain endothelial cell (BEC) death and damages tight junction integrity of the blood-brain […]
Kavli Affiliate: Attila Losonczy | Authors: S. Wenceslao Evans, Dongqing Shi, Mariya Chavarha, Mark H. Plitt, Jiannis Taxidis, Blake Madruga, Siri C. van Keulen, Michelle M. Pang, Sharon Su, Fuu-Jiun Hwang, Guofeng Zhang, Austin Reese, Lagnajeet Pradhan, Jiang Lan Fan, Sungmoo Lee, Yu Liu, Carl-Mikael Suomivuori, Dongyun Jiang, Adrian Negrean, Sui Wang, Na Ji, Thomas […]