Production of brain-derived neurotrophic factor gates plasticity in developing visual cortex

Kavli Affiliate: Michael Stryker | Authors: Megumi Kaneko and Michael P Stryker | Summary: Abstract We have previously shown that recovery of visual responses to a deprived eye during the critical period in mouse primary visual cortex (V1) requires both export of mRNA encoding brain derived neurotrophic factor (BDNF) to the dendrites of cortical cells […]


Continue.. Production of brain-derived neurotrophic factor gates plasticity in developing visual cortex

Basolateral amygdala and orbitofrontal cortex, but not dorsal hippocampus, are necessary for the control of reward-seeking by occasion setters

Kavli Affiliate: Patricia Janak | Authors: Kurt M Fraser and Patricia H Janak | Summary: ABSTRACT Reward-seeking in the world is driven by cues that can have ambiguous predictive and motivational value. To produce adaptive, flexible reward-seeking it is necessary to exploit occasion setters, other distinct features in the environment, to resolve the ambiguity of […]


Continue.. Basolateral amygdala and orbitofrontal cortex, but not dorsal hippocampus, are necessary for the control of reward-seeking by occasion setters

Microcephaly-associated WDR62 mutations hamper Golgi apparatus-to-spindle pole shuttling in human neural progenitors

Kavli Affiliate: Angeliki Louvi | Authors: Claudia dell’Amico, Marilyn Marlene Angulo Salavarria, Yutaka Takeo, Ichiko Saotome, Maria Teresa Dell’Anno, Maura Galimberti, Enrica Pellegrino, Elena Cattaneo, Angeliki Louvi and Marco Onorati | Summary: Abstract WDR62 is a spindle pole-associated scaffold protein with pleiotropic functions during corticogenesis. Recessive mutations in WDR62 are associated with structural brain abnormalities […]


Continue.. Microcephaly-associated WDR62 mutations hamper Golgi apparatus-to-spindle pole shuttling in human neural progenitors

Allosteric Regulation of a Synaptic Vesicle Glutamate Transporter

Kavli Affiliate: Robert Edwards | Authors: Fei Li, Jacob Eriksen, Juan A Oses-Prieto, Yessica K Gomez, Hongfei Xu, Janet Finer-Moore, Phuong Nguyen, Alisa Bowen, Andrew Nelson, Alma Burlingame, Michael Grabe, Robert Stroud and Robert Edwards | Summary: Abstract Concentration of neurotransmitter inside synaptic vesicles (SVs) underlies the quantal nature of synaptic transmission. In contrast to […]


Continue.. Allosteric Regulation of a Synaptic Vesicle Glutamate Transporter

Encoding of Dynamic Facial Information in the Middle Dorsal Face Area

Kavli Affiliate: Winrich Freiwald | Authors: Zetian Yang and Winrich A. Freiwald | Summary: Abstract Faces in motion reveal a plethora of information through visual dynamics. Faces can move in complex patterns while transforming facial shape, e.g. during the generation of different emotional expressions. While motion and shape processing have been studied extensively in separate […]


Continue.. Encoding of Dynamic Facial Information in the Middle Dorsal Face Area

Neuronal Activity Alters Neuron to OPC Synapses

Kavli Affiliate: Samuel Pleasure | Authors: Daniela S Moura, Alekhya Parvathaneni, Atehsa Sahagun, Hirofumi Noguchi, Iris Tilton, Emma Brennan, Robert M Brock, Lindsay R. Halladay, Samuel J Pleasure and Laura A. Cocas | Summary: Abstract The mechanisms that drive the timing and specificity of oligodendrocyte myelination during development, or remyelination after injury or immune attack […]


Continue.. Neuronal Activity Alters Neuron to OPC Synapses

Cortical surface electrical potentials are composed of multiple bandlimited frequency components, including high-gamma

Kavli Affiliate: Kristofer Bouchard, Edward Chang | Authors: Jesse A Livezey, Ahyeon Hwang, Kseniya Usovich, Maximilian Dougherty, Edward F Chang and Kristofer E Bouchard | Summary: A common challenge in neuroscience is how to decompose noisy, multi-source signals measured in experiments into biophysically interpretable components. Analysis of cortical surface electrical potentials (CSEPs) measured using electrocorticography […]


Continue.. Cortical surface electrical potentials are composed of multiple bandlimited frequency components, including high-gamma

Oxytocin receptor is not required for social attachment in prairie voles

Kavli Affiliate: Devanand Manoli | Authors: Kristen M. Berendzen, Ruchira Sharma, Maricruz Alvarado, YiChao Wei, Forrest D. Rogers, Adele Seelke, Trenton C. Simmons, Jessica Bond, Rose D. Larios, Michael Sherman, Srinivas Parthasarathy, Isidero Espineda, Joseph R. Knoedler, Annaliese Beery, Karen L. Bales, Nirao M Shah and Devanand S. Manoli | Summary: Prairie voles are among […]


Continue.. Oxytocin receptor is not required for social attachment in prairie voles

Suboptimal phenotypic reliability impedes reproducible human neuroscience

Kavli Affiliate: Joshua Vogelstein | Authors: Aki Nikolaidis, Andrew An Chen, Xiaoning He, Russell Shinohara, Joshua Vogelstein, Michael Milham and Haochang Shou | Summary: Biomarkers of behavior and psychiatric illness for cognitive and clinical neuroscience remain out of reach. Suboptimal reliability of biological measurements, such as functional magnetic resonance imaging (fMRI), is increasingly cited as […]


Continue.. Suboptimal phenotypic reliability impedes reproducible human neuroscience

Versatile Multiple Object Tracking in Sparse 2D/3D Videos Via Diffeomorphic Image Registration

Kavli Affiliate: Liam Paninski | Authors: James Yu, Amin Nejatbakhsh, Mahdi Torkashvand, Sahana Gangadharan, Maedeh Seyedolmohadesin, Jinmahn Kim, Liam Paninski and Vivek Venkatachalam | Summary: Tracking body parts in behaving animals, extracting fluorescence signals from cells embedded in deforming tissue, and analyzing cell migration patterns during development all require tracking objects with partially correlated motion. […]


Continue.. Versatile Multiple Object Tracking in Sparse 2D/3D Videos Via Diffeomorphic Image Registration