Kavli Affiliate: John Reynolds | Authors: Sachira Denagamage, Mitchell P. Morton, John H. Reynolds, Monika P. Jadi and Anirvan S. Nandy | Summary: Saccades are a ubiquitous and crucial component of our visual system, allowing for the efficient deployment of the fovea and its accompanying neural resources. Initiation of a saccade is known to cause […]
Kavli Affiliate: Tejal Desai | Authors: Joel A Finbloom, Preethi Raghavan, Michael Kwon, Bhushan N Kharbikar, Michelle A Yu and Tejal A Desai | Summary: Abstract New approaches are needed to treat bacterial biofilm infections, particularly those of Pseudomonas aeruginosa (PA), which have high rates of antimicrobial resistance and are commonly found in chronic wound […]
Kavli Affiliate: Li Zhao | Authors: Evan Witt, Christopher B Langer, Nicolas Svetec and Li Zhao | Summary: Abstract Aging is a complex biological process that is accompanied by changes in gene expression and mutational load. In many species, including humans, older fathers pass on more paternally-derived de novo mutations; however, the cellular basis and […]
Kavli Affiliate: Edward Chang | Authors: DANQING ZHU, David H Brookes, Akosua Busia, Ana Carneiro, Clara Fannjiang, Galina Popova, David Shin, Edward F Chang, Tomasz J. Nowakowski, Jennifer Listgarten and David V Schaffer | Summary: Abstract Adeno-associated viruses (AAVs) hold tremendous promise as delivery vectors for clinical gene therapy, but they need improvement. AAVs with […]
Kavli Affiliate: John Reynolds | Authors: Kandarp Dave, Donna B Stolz, Venugopal R Venna, Victoria A. Quaicoe, Michael E Maniskas, Michael John Reynolds, Riyan Babidhan, Duncan X Dobbins, Maura N. Farinelli, Abigail Sullivan, Tarun N. Bhatia, Hannah Yankello, Rohan Reddy, Younsoo Bae, Rehana K Leak, Sruti Shiva, Louise D McCullough and Devika Soundara Manickam | […]
Kavli Affiliate: John Reynolds | Authors: Kandarp Dave, Donna B Stolz, Michael John Reynolds, Riyan Babidhan, Duncan X Dobbins, Tarun N. Bhatia, Hannah Yankello, Rohan Reddy, Younsoo Bae, Rehana K Leak, Sruti Shiva and Devika Soundara Manickam | Summary: Ischemic stroke causes brain endothelial cell (BEC) death and damages tight junction integrity of the blood-brain […]
Kavli Affiliate: Attila Losonczy | Authors: S. Wenceslao Evans, Dongqing Shi, Mariya Chavarha, Mark H. Plitt, Jiannis Taxidis, Blake Madruga, Siri C. van Keulen, Michelle M. Pang, Sharon Su, Fuu-Jiun Hwang, Guofeng Zhang, Austin Reese, Lagnajeet Pradhan, Jiang Lan Fan, Sungmoo Lee, Yu Liu, Carl-Mikael Suomivuori, Dongyun Jiang, Adrian Negrean, Sui Wang, Na Ji, Thomas […]
Kavli Affiliate: Jonathan Whitlock, Jingyi Guo, Pearl Saldanha | Authors: Jingyi Guo Fuglstad, Pearl Saldanha, Jacopo Paglia and Jonathan R. Whitlock | Summary: Abstract Recording technologies for rodents have seen huge advances in the last decade, allowing users to sample thousands of neurons simultaneously from multiple brain regions. This has prompted the need for digital […]
Kavli Affiliate: Daphna Shohamy | Authors: David L Barack, Akram Bakkour, Daphna Shohamy and C Daniel Salzman | Summary: Abstract In the real world, making sequences of decisions to achieve goals often depends upon the ability to learn aspects of the environment that are not directly perceptible. Learning these so-called latent features requires seeking information […]
Kavli Affiliate: Michael Keiser | Authors: Laura M Gunsalus, Michael J. Keiser and Katherine S Pollard | Summary: ABSTRACT Predictive remapping — the ability of cells in retinotopic brain areas to transiently exhibit spatio-temporal retinotopic shifts beyond the spatial extent of their classical receptive fields — has been proposed as a primary mechanism that stabilizes […]