Neuroscience – Page 122 – Kavli Institute Pre-Print Publications

Cell-specific regulation of gene expression using splicing-dependent frameshifting.

Posted by klaurent March 2, 2022March 10, 2022Hopkins

Kavli Affiliate: Dwight Bergles, Seth Blackshaw, Richard Huganir, Patrick Kanold, Kristina Nielsen | Authors: Jonathan Ling, Alexei Bygrave, Clayton Santiago, Rogger Carmen, Vickie Trinh, Minzhong Yu, Yini Li, Jeong Han, Kamil Taneja, Ying Liu, Rochinelle Dongmo, Travis Babola, Patrick Parker, Lizhi Jiang, Patrick Leavey, Jennifer Smith, Rachel Vistein, Megan Gimmen, Benjamin Dubner, Patric Teodorescu, THEODOROS […]

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Spatially distributed computation in cortical circuits

Posted by klaurent March 1, 2022March 10, 2022UCSD / Salk

Kavli Affiliate: Thomas Albright | Authors: Sergei Gepshtein, Ambarish Pawar, Sunwoo Kwon, Sergey Savel’ev and Thomas D Albright | Summary: The traditional view of neural computation in the cerebral cortex holds that sensory neurons are specialized, i.e., selective for certain dimensions of sensory stimuli. This view was challenged by evidence of contextual interactions between stimulus […]

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Loss of functional heterogeneity along the CA3 transverse axis in aging

Posted by klaurent March 1, 2022March 10, 2022Hopkins

Kavli Affiliate: Michela Gallagher, James Knierim | Authors: Heekyung Lee, Zitong Wang, Arjuna Tilekeratne, Nick Lukish, Scott Zeger, Michela Gallagher and James J Knierim | Summary: Age-related deficits in pattern separation have been postulated to bias the output of hippocampal memory processing toward pattern completion, which can cause deficits in accurate memory retrieval. While the […]

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The role of liver fat in cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition

Posted by klaurent February 28, 2022March 10, 2022UCSD / Salk

Kavli Affiliate: Anders Dale | Authors: Dennis van der Meer, Tiril P Gurholt, Ida E Sonderby, Alexey Shadrin, Guy FL Hindley, Zillur Rahman, Ann-Marie Glaso de Lange, Oleksandr Frei, Olof D Leinhard, Jennifer Linge, Rozalyn Simon, Lars T. Westlye, Sigrun Halvorsen, Anders Dale, Tom H Karlsen, Tobias Kaufmann and Ole A Andreassen | Summary: Background […]

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Cortical ripples in humans

Posted by klaurent February 28, 2022March 10, 2022UCSD / Salk

Kavli Affiliate: Eric Halgren | Authors:Charles W Dickey, Ilya A Verzhbinsky, Xi Jiang, Burke Q Rosen, Sophie Kajfez, Emad N Eskandar, Jorge Gonzalez-Martinez, Sydney S Cash and Eric Halgren | Summary: Hippocampal ripples index the reconstruction of spatiotemporal neuronal firing patterns essential for the consolidation of memories in the cortex during non-rapid eye movement sleep […]

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Conserved neuropeptidergic regulation of intestinal integrity in invertebrate models of aging

Posted by klaurent February 28, 2022March 10, 2022UCSD / Salk

Kavli Affiliate: Sreekanth Chalasani, Ethan Bier | Authors: Anupama Singh, Bhagyashree Kaduskar, Kirthi C Reddy, Caroline Kumsta, Ethan Bier, Malene Hansen and Sreekanth H Chalasani | Summary: Age-related decline in intestinal barrier function impacts survival across species, but the underlying cell intrinsic and extrinsic factors remain unclear. Here, we demonstrate a role for neuropeptides in […]

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Dynamic Interrogation of Stochastic Transcriptome Trajectories Using Disease Associated Genes Reveals Distinct Origins of Neurological and Neuropsychiatric Disorders

Posted by klaurent February 27, 2022March 7, 2022UCSD / Salk

Kavli Affiliate: Fred Gage, Terrence Sejnowski | Authors: Thodoros Bermperidis, Simon Schafer, Fred H. Gage, Terrence Sejnowski and Elizabeth B Torres | Summary: The advent of open access to genomic data offers new opportunities to revisit old clinical debates while approaching them from a different angle. We examine anew the question of whether psychiatric and […]

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Widespread ripples synchronize human cortical activity during sleep, waking, and memory recall

Posted by klaurent February 27, 2022March 7, 2022UCSD / Salk

Kavli Affiliate: Eric Halgren | Authors: Charles W Dickey, Ilya A Verzhbinsky, Xi Jiang, Burke Q Rosen, Sophie Kajfez, Brittany Stedelin, Jerry J Shih, Sharona Ben-Haim, Ahmed M Raslan, Emad N Eskandar, Jorge Gonzalez-Martinez, Sydney S Cash and Eric Halgren | Summary: Declarative memory encoding, consolidation, and retrieval require the integration of elements encoded in […]

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The incentive circuit: memory dynamics in the mushroom body of Drosophila melanogaster

Posted by klaurent February 25, 2022March 7, 2022Yale

Kavli Affiliate: Michael Nitabach | Authors: Evripidis Gkanias, Li Yan McCurdy, Michael N Nitabach and Barbara Webb | Summary: Insects adapt their response to stimuli, such as odours, according to their pairing with positive or negative reinforcements, such as sugar or shock. Recent electrophysiological and imaging findings in Drosophila melanogaster allow detailed examination of the […]

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Dynamic Synchronization between Hippocampal Spatial Representations and the Stepping Rhythm

Posted by klaurent February 25, 2022March 7, 2022UCSF

Kavli Affiliate: Loren Frank | Authors: Abhilasha Joshi, Eric L. Denovellis, Abhijith Mankili, Yagiz Meneksedag, Thomas Davidson, Anna K Gillespie, Jennifer Ann Guidera, Demetris Roumis and Loren M. Frank | Summary: The hippocampus is a vertebrate brain structure that expresses spatial representations1 and is critical for navigation2,3. Navigation in turn intricately depends on locomotion; however, […]

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