Kavli Affiliate: Kay Tye | Authors: Chris A Leppla, Laurel Keyes, Gordon Glober, Gillian A Matthews, Kanha Batra, Maya Jay, Yu Feng, Hannah S Chen, Fergil Mills, Jeremy Delahanty, Jake Olsen, Edward H Nieh, Praneeth Namburi, Craig Wildes, Romy Wichmann, Anna Beyelar, Eyal Y Kimchi and Kay M. Tye | Summary: Rationale The basolateral amygdala […]
Kavli Affiliate: Denis Wirtz | Authors: Alexander T.F. Bell, Jacob T. Mitchell, Ashley L. Kiemen, Kohei Fujikura, Helen Fedor, Bonnie Gambichler, Atul Deshpande, Pei-Hsun Wu, Dimitrios N Sidiropoulos, Rossin Erbe, Jacob Stern, Rena Chan, Stephen Williams, James M. Chell, Jacquelyn W Zimmerman, Denis Wirtz, Elizabeth M. Jaffee, Laura D. Wood, Elana J. Fertig and Luciane […]
Kavli Affiliate: Richard Huganir | Authors: William Dylan Hale, Thomas C. Sudhof and Richard L. Huganir | Summary: In multicellular organisms, cell-adhesion molecules connect cells into tissues and mediate intercellular signaling between these cells. In vertebrate brains, synaptic cell-adhesion molecules (SAMs) guide the formation, specification, and plasticity of synapses. Some SAMs, when overexpressed in cultured […]
Kavli Affiliate: John Reynolds, Kenneth Miller | Authors: Alessandro Sanzeni, Agostina Palmigiano, Tuan H Nguyen, Junxiang Luo, Jonathan J Nassi, John H Reynolds, Mark H Histed, Kenneth D Miller and Nicolas Brunel | Summary: The ability to observe the response of neural circuits to controlled optogenetic perturbations opens an unprecedented window into the mechanisms governing […]
Kavli Affiliate: John Carlson | Authors: Wanyue Wang, Hany K M Dweck, Gaëlle J.S. Talross, Ali Zaidi, Joshua M Gendron and John R Carlson | Summary: The agricultural pest Drosophila suzukii differs from most other Drosophila species in that it lays eggs in ripe, rather than overripe, fruit. Previously we showed that changes in bitter […]
Kavli Affiliate: Takaki Komiyama | Authors: Saber Meamardoost, Eunjung Hwang, Mahasweta Bhattacharya, Chi Ren, Linbing Wang, Claudia Mewes, Ying Zhang, Takaki Komiyama and Rudiyanto Gunawan | Summary: The brain’s connectome continually rewires throughout the life of an organism. In this study, we sought to elucidate the operational principles of such rewiring by analyzing the functional […]
Kavli Affiliate: Jose Suarez Lopez | Authors: Liam Singer, Xenia Wietlisbach, Raffael Hickisch, Eva Maria Schoell, Angela Van den Broek, Manon Désalme, Koen Driesen, Mari Lyly, Francesca Marucco, Miroslav Kutal, Nives Pagon, Cristian Remus Papp, Paraskevi Milioni, Remigijus Uzdras, Ilgvars Zihmanis, Fridolin Zimmermann, Katrina Marsden, Klaus Hackländer, José Vicente López-Bao, Sybille Klenzendorf and Daniel Wegmann […]
Kavli Affiliate: Kathleen Cullen | Authors: Cynthia R Steinhardt, Diana E Mitchell, Kathleen E Cullen and Gene Y Fridman | Summary: Electrical stimulation of neural responses is used both scientifically in brain mapping studies and in many clinical applications such as cochlear, vestibular, and retinal implants. Due to safety considerations, stimulation of the nervous system […]
Kavli Affiliate: David Linden | Authors: Friederike Ehrhart, Ana Silva, Therese Amelsvoort, Emma von Scheibler, Chris Evelo and David E.J. Linden | Summary: Schizophrenia genetics is complex, and the contribution of common and rare variants are not fully understood. Several specific copy number variations (CNVs) confer increased risk for schizophrenia, and the study of their […]
Kavli Affiliate: Reza Abbasi-Asl | Authors: Fatemeh Kamali, Amir Abolfazl Suratgar, Mohammadbagher Menhaj and Reza Abbasi-Asl | Summary: Voxel-wise encoding models based on convolutional neural networks (CNNs) have emerged as state-of-the-art predictive models of brain activity evoked by natural movies. Despite the superior predictive performance of CNN-based models, the huge number of parameters in these […]