Brain-wide mapping of oligodendrocyte organization and oligodendrogenesis across the murine lifespan

Kavli Affiliate: Dwight Bergles | Authors: Yu Kang T Xu, Abigail Bush, Ephraim Musheyev, Anya A Kim, Sen Zhang, Jaime Eugenin von Bernhardi, Jeremias Sulam and Dwight E Bergles | Summary: Insulating sheaths of myelin accelerate neuronal signaling in complex networks of the mammalian brain. In the CNS, myelin sheaths are exclusively produced by oligodendrocytes, […]


Continue.. Brain-wide mapping of oligodendrocyte organization and oligodendrogenesis across the murine lifespan

Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function

Kavli Affiliate: Kathleen Cullen | Authors: Kazuya Ono, Amandine Jarysta, Natasha C. Hughes, Alma Jukic, Hui Ho Vanessa Chang, Michael R Deans, Ruth Anne Eatock, Kathleen E Cullen, Katie S Kindt and Basile Tarchini | Summary: Otolith organs in the inner ear and neuromasts in the fish lateral-line harbor two populations of hair cells oriented […]


Continue.. Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function

Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness

Kavli Affiliate: Michael Beer | Authors: Bess P. Rosen, Qing V. Li, Hyein S. Cho, Dingyu Liu, Dapeng Yang, Sarah Graff, Jielin Yan, Renhe Luo, Nipun Verma, Jeyaram R. Damodaran, Hanuman T. Kale, Samuel J. Kaplan, Michael A. Beer, Simone Sidoli and Danwei Huangfu | Summary: Pluripotent stem cells are defined by their self-renewal capacity, […]


Continue.. Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness

Effects of connectivity hyperalignment (CHA) on estimated brain network properties: from coarse-scale to fine-scale

Kavli Affiliate: Martin Lindquist | Authors: Farzad V. Farahani, Mary Beth Nebel, Tor Wager and Martin A. Lindquist | Summary: Recent gains in functional magnetic resonance imaging (fMRI) studies have been driven by increasingly sophisticated statistical and computational techniques and the ability to capture brain data at finer spatial and temporal resolution. These advances allow […]


Continue.. Effects of connectivity hyperalignment (CHA) on estimated brain network properties: from coarse-scale to fine-scale

Solving the “Blind men and the elephant problem”: Additive deep learning of complex high dimensional models from partial faceted datasets

Kavli Affiliate: Denis Wirtz | Authors: Yufei Wu, Pei-Hsun Wu, Allison Chambliss, Denis Wirtz and Sean Sun | Summary: Summary: Biological systems are complex networks involving tens of thousands of interacting molecular components, and measurable biological functions are emerging properties of these complex networks. Many quantitative studies in biology attempt to connect biological function with […]


Continue.. Solving the “Blind men and the elephant problem”: Additive deep learning of complex high dimensional models from partial faceted datasets

A Real-time Multi-Subject Three Dimensional Pose Tracking System for Analyzing Social Behaviors of Non-human Primates

Kavli Affiliate: Xiaoqin Wang | Authors: Chaoqun Cheng, Zijian Huang, Ruiming Zhang, Guozheng Huang, Han Wang, Likai Tang and Xiaoqin Wang | Summary: Summary: The ability to track positions and poses (body parts) of multiple monkeys in a 3D space in real time is highly desired by non-human primate (NHP) researchers in behavioral and systems […]


Continue.. A Real-time Multi-Subject Three Dimensional Pose Tracking System for Analyzing Social Behaviors of Non-human Primates

Functional Regrowth of Norepinephrine Axons in the Adult Mouse Brain Following Injury

Kavli Affiliate: David Linden | Authors: Patrick R Cooke and David J Linden | Summary: Summary: It is widely believed that axons in the central nervous system of adult mammals do not regrow following injury. This failure is thought, at least in part, to underlie the limited recovery of function following injury to the brain […]


Continue.. Functional Regrowth of Norepinephrine Axons in the Adult Mouse Brain Following Injury

CellCover Captures Neural Stem Cell Progression in Mammalian Neocortical Development

Kavli Affiliate: Jean Fan and Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Summary: Definition of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Marker […]


Continue.. CellCover Captures Neural Stem Cell Progression in Mammalian Neocortical Development

CellCover Defines Temporal Progression in Conserved Cell Types and Informs oRG Evolution using scRNA-seq Data in Mammalian Neocortical Development

Kavli Affiliate: Donald Geman and Laurent Younes | Authors: Lanlan Ji, An Wang, Shreyash Sonthalia, Daniel Q Naiman, Laurent Younes, Carlo Colantuoni and Donald Geman | Summary: Accurate identification of cell classes across the tissues of living organisms is central in the analysis of growing atlases of single-cell RNA sequencing (scRNA-seq) data across biomedicine. Such […]


Continue.. CellCover Defines Temporal Progression in Conserved Cell Types and Informs oRG Evolution using scRNA-seq Data in Mammalian Neocortical Development

Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage

Kavli Affiliate: Jean Fan | Authors: Katy Boerner, Philip D Blood, Jonathan C Silverstein, Matthew Ruffalo, Sarah A Teichmann, Gloria Pryhuber, Ravi S Misra, Jeffrey M Purkerson, Jean Fan, John W Hickey, Gesmira Molla, Chuan Xu, Yun Zhang, Griffin M Weber, Yashvardhan Jain, Danial Qaurooni, Yongxin Kong, Andreas Bueckle and Bruce W Herr II | […]


Continue.. Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage