Kavli Affiliate: Franck Polleux | Authors: Koki Nakamura, Saeko Aoyama-Ishiwatari, Takahiro Nagao, Mohammadreza Paaran, Christopher J. Obara, Yui Sakurai-Saito, Jake Johnston, Yudan Du, Shogo Suga, Masafumi Tsuboi, Makoto Nakakido, Kouhei Tsumoto, Yusuke Kishi, Yukiko Gotoh, Chulhwan Kwak, Hyun-Woo Rhee, Jeong Kon Seo, Hidetaka Kosako, Clint Potter, Bridget Carragher, Jennifer Lippincott-Schwartz, Franck Polleux and Yusuke Hirabayashi […]

Kavli Affiliate: Liam Paninski | Authors: Julien Boussard, Charlie Windolf, Cole Hurwitz, Hyun Dong Lee, Han Yu, Olivier Winter and Liam Paninski | Summary: With the advent of high-density, multi-electrode probes, there has been a renewed interest in developing robust and scalable algorithms for spike sorting. Current spike sorting approaches, however, struggle to deal with […]

Kavli Affiliate: Sarah Woolley | Authors: Mila Bertolo, Daniel Müllensiefen, Isabelle Peretz, Sarah C. Woolley, Jon T. Sakata and Samuel A. Mehr | Summary: Since Darwin1, researchers have proposed that human musicality evolved in a reproductive context in which males produce music to signal their mate quality to females. Sexually selected traits involve tradeoffs in […]

Kavli Affiliate: Daphna Shohamy | Authors: Kenneth Kay, Natalie Biderman, Ramin Khajeh, Manuel Beiran, Christopher J Cueva, Daphna Shohamy, Greg Jensen, Xue-Xin Wei, Vincent P Ferrera and L F Abbott | Summary: Relational cognition — the ability to infer relationships that generalize to novel combinations of objects — is fundamental to human and animal intelligence. […]

Kavli Affiliate: Steven Siegelbaum | Authors: Pegah Kassraian, Shivani K. Bigler, Diana M. Gilly, Neilesh Shrotri and Steven A. Siegelbaum | Summary: The ability to distinguish a threatening from non-threatening conspecific based on past experience is critical for adaptive social behaviors. Although recent progress has been made in identifying the neural circuits that contribute to […]

Kavli Affiliate: Liam Paninski | Authors: Benjamin Antin, Masato Sadahiro, Marta Gajowa, Marcus A. Triplett, Hillel Adesnik and Liam Paninski | Summary: Monosynaptic connectivity mapping is crucial for building circuit-level models of neural computation. Two-photon optogenetic stimulation, when combined with whole-cell recordings, has the potential to map monosynaptic connectivity at an unprecedented scale. However, optogenetic […]

Kavli Affiliate: Rudy Behnia | Authors: Matthias P Christenson, Alvaro Sanz Diez, Sarah L Heath, Maia Saavedra-Weisenhaus, Atsuko Adashi, LF Abbott and Rudy Behnia | Summary: A universal principle of sensory perception is the progressive transformation of sensory information from broad non-specific signals to stimulus-selective signals that form the basis of perception. To perceive color, […]

Kavli Affiliate: Robert Hawkins | Authors: Kerriann K Badal, Abhishek Sadhu, Carrie McCracken, Bindu L Raveendra, Sebastian Lozano-Villada, Amol C Shetty, Phillip Gillette, Yibo Zhao, Dustin Stommes, Lynne A Fieber, Michael C Schmale, Anup Mahurkar, Robert D Hawkins and Sathyanarayanan V Puthanveettil | Summary: Molecular mechanisms underlying aging associated impairments in learning and long-term memory […]

Kavli Affiliate: Michael Shadlen | Authors: Anne Löffler, Ariel Zylberberg, Michael N. Shadlen and Daniel M Wolpert | Summary: Deciding how difficult it is going to be to perform a task allows us to choose between tasks, allocate appropriate resources, and predict future performance. To be useful for planning, difficulty judgments should not require completion […]

Kavli Affiliate: Liam Paninski | Authors: Marcus A Triplett, Marta Gajowa, Hillel Adesnik and Liam Paninski | Summary: Two-photon optogenetics has transformed our ability to probe the structure and function of neural circuits. However, achieving precise optogenetic control of neural ensemble activity has remained fundamentally constrained by the problem of off-target stimulation (OTS): the inadvertent […]