Kavli Affiliate: Steven Siegelbaum; | Authors: Lara M. Boyle, Wanhui Sheng, Felix Leroy, Rhea Sahai, Sarah Irfan, Heon-Jin Lee, Andres Villegas, W. Scott Young and Steven A Siegelbaum | Summary: Although it is well-known that the hippocampus mediates declarative memory (the repository of information of people, places, things and events) and influences behavior, the differential […]

Kavli Affiliate: Franck Polleux; | Authors: Sergio B. Garcia, Alexa P. Schlotter, Daniela Pereira, Franck Polleux and Luke Hammond | Summary: Accurate and unbiased reconstructions of neuronal morphology, including quantification of dendritic spine morphology and distribution, are widely used in neuroscience but remain a major roadblock for large-scale analysis. Traditionally, spine analysis has required labor-intensive […]

Kavli Affiliate: Franck Polleux; | Authors: Koki Nakamura, Saeko Aoyama-Ishiwatari, Takahiro Nagao, Mohammadreza Paaran, Christopher J. Obara, Yui Sakurai-Saito, Jake Johnston, Yudan Du, Shogo Suga, Masafumi Tsuboi, Makoto Nakakido, Kouhei Tsumoto, Yusuke Kishi, Yukiko Gotoh, Chulhwan Kwak, Hyun-Woo Rhee, Jeong Kon Seo, Hidetaka Kosako, Clint Potter, Bridget Carragher, Jennifer Lippincott-Schwartz, Franck Polleux and Yusuke Hirabayashi […]

Kavli Affiliate: Liam Paninski | Authors: Pojeong Park, J. David Wong-Campos, Daniel Itkis, Byung Hun Lee, Yitong Qi, Hunter C. Davis, Benjamin Antin, Amol Praveen Pasarkar, Jonathan B. Grimm, Sarah E. Plutkis, Katie L. Holland, Liam Paninski, Luke Lavis and Adam Ezra Cohen | Summary: Dendrites on neurons support nonlinear electrical excitations, but the computational […]

Kavli Affiliate: Wei Min | Authors: Sushmitha Sriramulu, Shivani Thoidingjam, Wei-Min Chen, Oudai Hassan, Farzan Siddiqui, Stephen L Brown, Benjamin Movsas, Michael D Green, Anthony J Davis, Corey Speers, Eleanor Walker and Shyam Nyati | Summary: Background Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer subtype often treated with radiotherapy (RT). […]

Kavli Affiliate: Michael Shadlen | Authors: Natalie A Steinemann, Gabriel M Stine, Eric M Trautmann, Ariel Zylberberg, Daniel M Wolpert and Michael N Shadlen | Summary: Neurobiological investigations of perceptual decision-making have furnished the first glimpse of a flexible cognitive process at the level of single neurons (Shadlen and Newsome, 1996; Shadlen and Kiani, 2013). […]

Kavli Affiliate: Steven Siegelbaum | Authors: Andres Villegas and Steven A Siegelbaum | Summary: The dorsal CA2 subregion (dCA2) of the hippocampus exerts a critical role in social novelty recognition (SNR) memory and in the promotion of social aggression. Whether the social aggression and SNR memory functions of dCA2 are related or represent independent processes […]

Kavli Affiliate: Daphna Shohamy | Authors: Peter Jendrichovsky, Hey-Kyoung Lee and Patrick O Kanold | Summary: Patients with Parkinsons disease are impaired at incremental reward-based learning. It is typically assumed that this impairment reflects a loss of striatal dopamine. However, many open questions remain about the nature of reward-based learning deficits in Parkinsons. Recent studies […]

Kavli Affiliate: Liam Paninski | Authors: Claire P. Everett, Amy L. Norovich, Jessica E. Burke, Matthew R Whiteway, Pei-Yin Shih, Yuyang Zhu, Liam Paninski and Andres Bendesky | Summary: Animals coordinate their behavior with each other during both cooperative and agonistic social interactions. Such coordination often adopts the form of “turn taking”, in which the […]

Kavli Affiliate: Liam Paninski | Authors: Samaher Fageiry, Claire L Warriner, Jackson Loper, Liam Paninski, Thomas Reardon, Thomas M. Jessell, Rui M. Costa and Andrew Miri | Summary: The corticospinal tract exerts its influence on movement through spinal neurons, which can be divided into types that exhibit distinct functions. However, it remains unknown whether these […]