Kavli Affiliate: Michael Goldberg | Authors: Michael E Goldberg, Michelle D Noyes, Evan E Eichler, Aaron Quinlan and Kelley Harris | Summary: Short tandem repeats (STRs) are hotspots of genomic variability in the human germline because of their high mutation rates, which have long been attributed largely to polymerase slippage during DNA replication. This model […]
Continue.. Effects of parental age and polymer composition on short tandem repeat de novo mutation rates