Correlation functions quantify super-resolution images and estimate apparent clustering due to over-counting

Kavli Affiliate: Barbara Baird | First 5 Authors: Sarah Veatch, Benjamin Machta, Sarah Shelby, Ethan Chiang, David Holowka | Summary: We present an analytical method to quantify clustering in super-resolution localization images of static surfaces in two dimensions. The method also describes how over-counting of labeled molecules contributes to apparent self-clustering and how the effective […]


Continue.. Correlation functions quantify super-resolution images and estimate apparent clustering due to over-counting

Opportunities and limitations of transition voltage spectroscopy: a theoretical analysis

Kavli Affiliate: Joseph M. Thijssen | First 5 Authors: Fatemeh Mirjani, Joseph M. Thijssen, Sense Jan van der Molen, , | Summary: In molecular charge transport, transition voltage spectroscopy (TVS) holds the promise that molecular energy levels can be explored at bias voltages lower than required for resonant tunneling. We investigate the theoretical basis of […]


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Finite Phase-separation FRET II: Determination of domain size from simulated data

Kavli Affiliate: Gerald W. Feigenson | First 5 Authors: Frederick A. Heberle, Gerald W. Feigenson, , , | Summary: We have developed a new model to describe FRET efficiency (E FRET) between freely-diffusing membrane probes in phase-separated bilayers (Finite Phase-separation FRET, or FP-FRET), that in principle applies to any system where phase domain dimensions are […]


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Finite Phase-separation FRET I: A quantitative model valid for bilayer nanodomains

Kavli Affiliate: Gerald W. Feigenson | First 5 Authors: Frederick A. Heberle, Gerald W. Feigenson, , , | Summary: Multicomponent lipid mixtures exhibit complex phase behavior, including coexistence of nanoscopic fluid phases in ternary mixtures mimicking the composition of the outer leaflet of mammalian plasma membrane. The physical mechanisms responsible for the small size of […]


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Limited Perturbation of a DPPC Bilayer by Fluorescent Lipid Probes: A Molecular Dynamics Study

Kavli Affiliate: Gerald W. Feigenson | First 5 Authors: Frederick A. Heberle, David G. Ackerman, Gerald W. Feigenson, , | Summary: The presence and the properties of lipid bilayer nanometer-scale domains might be important for understanding the membranes of living cells. We used molecular dynamics (MD) simulations to investigate perturbations of a small patch of […]


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Digital Plasmonics

Kavli Affiliate: Kobus Kuipers | First 5 Authors: Bergin Gjonaj, Jochen Aulbach, Patrick M. Johnson, Allard P. Mosk, Kobus Kuipers | Summary: The field of plasmonics offers a route to control light fields with metallic nanostructures through the excitation of Surface Plasmon Polaritons (SPPs). These surface waves, bound to a metal dielectric interface, tightly confine […]


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DFT-based many-body analysis of electron transport through molecules

Kavli Affiliate: Joseph M. Thijssen | First 5 Authors: Fatemeh Mirjani, Joseph M. Thijssen, , , | Summary: We present a method which uses density functional theory (DFT) to treat transport through a single molecule connected to two conducting leads for the weak and intermediate coupling. This case is not accessible to standard non-equilibrium Green’s […]


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Cross-link governed dynamics of biopolymer networks

Kavli Affiliate: Martin Depken | First 5 Authors: Chase P. Broedersz, Martin Depken, Norman Y. Yao, Martin R. Pollak, David A. Weitz | Summary: Cytoskeletal networks of biopolymers are cross-linked by a variety of proteins. Experiments have shown that dynamic cross-linking with physiological linker proteins leads to complex stress relaxation and enables network flow at […]


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