A Transiting Super-Earth in the Radius Valley and An Outer Planet Candidate Around HD 307842

Kavli Affiliate: Avi Shporer | First 5 Authors: Xinyan Hua, Sharon Xuesong Wang, Johanna K. Teske, Tianjun Gan, Avi Shporer | Summary: We report the confirmation of a TESS-discovered transiting super-Earth planet orbiting a mid-G star, HD 307842 (TOI-784). The planet has a period of 2.8 days, and the radial velocity (RV) measurements constrain the […]


Continue.. A Transiting Super-Earth in the Radius Valley and An Outer Planet Candidate Around HD 307842

Hill-top inflation from Dai-Freed anomaly in the standard model — A solution to the iso-curvature problem of the axion dark matter

Kavli Affiliate: Masahiro Kawasaki | First 5 Authors: Masahiro Kawasaki, Tsutomu T. Yanagida, , , | Summary: The discrete symmetry $Z_4$ in the standard model (SM) with three right-handed neutrinos is free from the Dai-Freed anomaly. Motivated by this $Z_4$ symmetry, we constructed a topological inflation model consistent with all known constraints and observations. However, […]


Continue.. Hill-top inflation from Dai-Freed anomaly in the standard model — A solution to the iso-curvature problem of the axion dark matter

Single-shot 3D photoacoustic computed tomography with a densely packed array for transcranial functional imaging

Kavli Affiliate: Lihong V. Wang | First 5 Authors: Rui Cao, Yilin Luo, Jinhua Xu, Xiaofei Luo, Ku Geng | Summary: Photoacoustic computed tomography (PACT) is emerging as a new technique for functional brain imaging, primarily due to its capabilities in label-free hemodynamic imaging. Despite its potential, the transcranial application of PACT has encountered hurdles, […]


Continue.. Single-shot 3D photoacoustic computed tomography with a densely packed array for transcranial functional imaging

Single-shot 3D photoacoustic computed tomography with a densely packed array for transcranial functional imaging

Kavli Affiliate: Lihong V. Wang | First 5 Authors: Rui Cao, Yilin Luo, Jinhua Xu, Xiaofei Luo, Ku Geng | Summary: Photoacoustic computed tomography (PACT) is emerging as a new technique for functional brain imaging, primarily due to its capabilities in label-free hemodynamic imaging. Despite its potential, the transcranial application of PACT has encountered hurdles, […]


Continue.. Single-shot 3D photoacoustic computed tomography with a densely packed array for transcranial functional imaging

Performing quantum entangled biphoton spectroscopy using classical light pulses

Kavli Affiliate: Birgitta Whaley | First 5 Authors: Liwen Ko, Robert L. Cook, K. Birgitta Whaley, , | Summary: We show that for a class of quantum light spectroscopy (QLS) experiments using n = 0,1,2,$cdots$ classical light pulses and an entangled photon pair (a biphoton state) where one photon acts as a reference without interacting […]


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Clonal neural tube organoids self-organise floorplate through BMP-mediated cluster competition

Kavli Affiliate: Eric D. Siggia | Authors: Teresa Krammer, Hannah Taylor Stuart, Elena Gromberg, Keisuke Ishihara, Manuela Melchionda, Jingkui Wang, Elena Costantini, Stefanie Lehr, Dillon Cislo, Laura Arbanas, Alexandra Hoermann, Ralph Alexander Neumueller, Nicola Elvassore, Eric Siggia, James Briscoe, Anna Kicheva and Elly Margaret Tanaka | Summary: Organoids can undergo pattern formation by spontaneously forming […]


Continue.. Clonal neural tube organoids self-organise floorplate through BMP-mediated cluster competition

A Chicken Tapasin ortholog can chaperone empty HLA molecules independently of other peptide-loading components

Kavli Affiliate: Michael W. Young | Authors: Georgia F Papadaki, Claire H Woodward, Michael C Young, Trenton J Winters, George M Burslem and Nikolaos G Sgourakis | Summary: Human Tapasin (hTapasin) is the main chaperone of MHC-I molecules, enabling peptide loading and antigen repertoire optimization across HLA allotypes. However, it is restricted to the endoplasmic […]


Continue.. A Chicken Tapasin ortholog can chaperone empty HLA molecules independently of other peptide-loading components

HD mutation results in a dominant negative effect on HTT function

Kavli Affiliate: Ali H. Brivanlou | Authors: Tiago L Laundos, Shu Li, Eric Cheang, Riccardo De Santis, Francesco M Piccolo and Ali H. Brivanlou | Summary: Huntington’s disease (HD) remains an incurable and fatal neurodegenerative disease long after CAG-expansion mutation in the huntingtin gene (HTT) was identified as the cause. The underlying pathological mechanism, whether […]


Continue.. HD mutation results in a dominant negative effect on HTT function

Multi-night naturalistic cortico-basal recordings reveal mechanisms of NREM slow wave suppression and spontaneous awakenings in Parkinson’s disease

Kavli Affiliate: Philip Starr | Authors: Md Fahim Anjum, Clay Smyth, Derk-Jan Dijk, Philip Starr, Timothy Denison and Simon Little | Summary: Background: Sleep disturbance is a prevalent and highly disabling comorbidity in individuals with Parkinson’s disease (PD) that leads to worsening of daytime symptoms, accelerated disease progression and reduced quality of life. Objectives: We […]


Continue.. Multi-night naturalistic cortico-basal recordings reveal mechanisms of NREM slow wave suppression and spontaneous awakenings in Parkinson’s disease

Oxysterol-liver X receptor signaling mediates CYFIP1 regulation of cortical neurogenesis

Kavli Affiliate: David Linden | Authors: Daniel C de la Fuente, Claudia Tamburini, Emily Stonelake, William J Griffiths, Jeremy Hall, Michael J Owen, David E. J. Linden, Andrew Pocklington, Yuqin Wang and Meng Li | Summary: Dysregulation in neural progenitor proliferation and neuronal differentiation has been increasingly recognised as a common pathology in neural cells […]


Continue.. Oxysterol-liver X receptor signaling mediates CYFIP1 regulation of cortical neurogenesis