Kavli Affiliate: Menno Witter | Authors: Christiana Bjorkli, Nora Cecilie Ebbesen, Joshua B Julian, Menno P Witter, Axel Sandvig and Ioanna Sandvig | Summary: One of the neuropathological hallmarks of Alzheimer’s disease (AD) is the accumulation of amyloid-β (Aβ) plaques, which is preceded by intraneuronal build-up of toxic, aggregated Aβ during disease progression. Aβ plaques […]
Continue.. Manipulation of neuronal activity in the entorhinal-hippocampal circuit affects intraneuronal amyloid-β levels