Single cell transcriptomic profiling of human brain organoids reveals developmental timing- and cell-type-specific vulnerabilities induced by NRXN1 CNVs in schizophrenia

Posted by klaurent Hopkins

Kavli Affiliate: Jin Kang | Authors: ChangHui Pak, Rebecca Sebastian, Kang Jin, Narciso Pavon, Ruby Bansal, Andrew Potter, Yoonjae Song, Juliana Babu, Rafael Gabriel, Yubing Sun and Bruce J Aronow | Summary: Abstract De novo mutations and copy number variations (CNVs) in NRXN1 (2p16.3) pose a significant risk for schizophrenia (SCZ). How NRXN1 CNVs impact […]


Continue.. Single cell transcriptomic profiling of human brain organoids reveals developmental timing- and cell-type-specific vulnerabilities induced by NRXN1 CNVs in schizophrenia

MicroRNA-218 instructs proper assembly of hippocampal networks

Posted by klaurent Rockefeller

Kavli Affiliate: Robert B. Darnell | Authors: Seth Taylor, Mariko Kobayashi, Antonietta Vilella, Durgesh Tiwari, Norjin Zolboot, Andrea Hartzell, Carol Girgiss, Yusuf Abaci, Claudia De Sanctis, Gian Carlo Bellenchi, Robert B Darnell, Christina Gross, Michele Zoli, Darwin K Berg and Giordano Lippi | Summary: ABSTRACT The assembly of the mammalian brain is orchestrated by temporally […]


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Simultaneous bounds on the gravitational dipole radiation and varying gravitational constant from compact binary inspirals

Posted by klaurent Peking

Kavli Affiliate: Lijing Shao | First 5 Authors: Ziming Wang, Junjie Zhao, Zihe An, Lijing Shao, Zhoujian Cao | Summary: Compact binaries are an important class of gravitational-wave (GW) sources that can be detected by current and future GW observatories. They provide a testbed for general relativity (GR) in the highly dynamical strong-field regime. Here, […]


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Variability Catalog of Stars Observed During the TESS Prime Mission

Posted by klaurent MIT

Kavli Affiliate: Roland Vanderspek | First 5 Authors: Tara Fetherolf, Joshua Pepper, Emilie Simpson, Stephen R. Kane, Teo Mocnik | Summary: During its 2-year Prime Mission, TESS observed over 232,000 stars at a 2-min cadence across ~70% of the sky. These data provide a record of photometric variability across a range of astrophysically interesting time […]


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Variability Catalog of Stars Observed During the TESS Prime Mission

Posted by klaurent MIT

Kavli Affiliate: Roland Vanderspek | First 5 Authors: Tara Fetherolf, Joshua Pepper, Emilie Simpson, Stephen R. Kane, Teo Mocnik | Summary: During its 2-year Prime Mission, TESS observed over 232,000 stars at a 2-min cadence across ~70% of the sky. These data provide a record of photometric variability across a range of astrophysically interesting time […]


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Decoding Measurement-Prepared Quantum Phases and Transitions: from Ising model to gauge theory, and beyond

Posted by klaurent UCSB

Kavli Affiliate: Matthew P. A. Fisher | First 5 Authors: Jong Yeon Lee, Wenjie Ji, Zhen Bi, Matthew P. A. Fisher, | Summary: Measurements allow efficient preparation of interesting quantum many-body states with long-range entanglement, conditioned on additional transformations based on measurement outcomes. Here, we demonstrate that the so-called conformal quantum critical points (CQCP) can […]


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Measurement-Prepared Quantum Criticality: from Ising model to gauge theory, and beyond

Posted by klaurent UCSB

Kavli Affiliate: Matthew P. A. Fisher | First 5 Authors: Jong Yeon Lee, Wenjie Ji, Zhen Bi, Matthew P. A. Fisher, | Summary: Measurements allow efficient preparation of interesting quantum many-body states exhibiting long-range, topological, or fractonic orders. Here, we prove that the so-called conformal quantum critical points (CQCP) can be obtained by performing general […]


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Human anti-ACE2 monoclonal antibodies as pan-sarbecovirus prophylactic agents

Posted by klaurent Rockefeller

Kavli Affiliate: Charles Rice | Authors: Fengwen Zhang, Jesse Jenkins, Renan V.H. de Carvalho, Sandra Nakandakari-Higa, Teresia Chen, Morgan E Abernathy, Elisabeth Nyakatura, David Andrew, Irina V. Lebedeva, Ivo C Lorenz, H.-Heinrich Hoffmann, Charles M. Rice, Gabriel D. Victora, Christopher O. Barnes, Theodora Hatziioannou and Paul D Bieniasz | Summary: Abstract Human monoclonal antibodies from […]


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Morpheus Reveals Distant Disk Galaxy Morphologies with JWST: The First AI/ML Analysis of JWST Images

Posted by klaurent Cambridge

Kavli Affiliate: Roberto Maiolino | First 5 Authors: Brant E. Robertson, Sandro Tacchella, Benjamin D. Johnson, Ryan Hausen, Adebusola B. Alabi | Summary: The dramatic first images with James Webb Space Telescope (JWST) demonstrated its power to provide unprecedented spatial detail for galaxies in the high-redshift universe. Here, we leverage the resolution and depth of […]


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Microwave spectroscopy of interacting Andreev spins

Posted by klaurent Delft

Kavli Affiliate: L. P. Kouwenhoven | First 5 Authors: J. J. Wesdorp, F. J. Matute-Caňadas, A. Vaartjes, L. Grünhaupt, T. Laeven | Summary: Andreev bound states are fermionic states localized in weak links between superconductors which can be occupied with spinful quasiparticles. Microwave experiments using superconducting circuits with InAs/Al nanowire Josephson junctions have recently enabled […]


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