Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized cortically differentiating human pluripotent stem cells

Kavli Affiliate: Seth Shipman | Authors: Manuel Peter, Seth Shipman and Jeffrey D Macklis | Summary: Differentiation of human pluripotent stem cells (hPSC) into distinct neuronal populations holds substantial potential for disease modeling in vitro, toward both elucidation of pathobiological mechanisms and screening of potential therapeutic agents. For successful differentiation of hPSCs into subtype-specific neurons […]


Continue.. Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized cortically differentiating human pluripotent stem cells

CaMKII autophosphorylation but not downstream kinase activity is required for synaptic memory

Kavli Affiliate: Roger Nicoll | Authors: XIUMIN CHEN, Qixu Cai, jing zhou, Samuel J Pleasure, Howard Schulman, Mingjie Zhang and Roger A Nicoll | Summary: CaMKII plays a critical role in long-term potentiation (LTP), a well-established model for learning and memory through the enhancement of synaptic transmission. Biochemical studies indicate that CaMKII catalyzes a phosphotransferase […]


Continue.. CaMKII autophosphorylation but not downstream kinase activity is required for synaptic memory

Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.

Kavli Affiliate: Mark Ellisman | Authors: Cristiane dos Santos, Shristi Shrestha, Matthew A Cottam, Guy Perkins, Varda Lev-Ram, Birbickram Roy, Christopher Acree, Keun-Young Kim, Thomas Deerinck, Melanie Cutler, Danielle Dean, Jean Philippe Cartailler, Patrick E MacDonald, Martin W Hetzer, Mark H Ellisman and Rafael Arrojo e Drigo | Summary: Caloric restriction (CR) extends organismal lifespan […]


Continue.. Caloric restriction promotes beta cell longevity and delays aging and senescence by enhancing cell identity and homeostasis mechanisms.

iATPSnFR2: a high dynamic range fluorescent sensor for monitoring intracellular ATP

Kavli Affiliate: Timothy A. Ryan, Timothy Brown | Authors: Jonathan S Marvin, Alexandros C Kokotos, Mukesh Kumar, Camila Pulido, Ariana N Tkachuk, Jocelyn Shuxin Yao, Timothy A Brown and Timothy A Ryan | Summary: We developed a significantly improved genetically encoded quantitative adenosine triphosphate (ATP) sensor to provide real-time dynamics of ATP levels in subcellular […]


Continue.. iATPSnFR2: a high dynamic range fluorescent sensor for monitoring intracellular ATP

VLBI Observations of a sample of Palomar-Green quasars II: characterising the parsec-scale radio emission

Kavli Affiliate: Luis C. Ho | First 5 Authors: Ailing Wang, Tao An, Yingkang Zhang, Xiaopeng Cheng, Luis C. Ho | Summary: This study uses multi-frequency Very Long Baseline Interferometry (VLBI) to study the radio emission from 10 radio-quiet quasars (RQQs) and four radio-loud quasars (RLQs). The diverse morphologies, radio spectra, and brightness temperatures observed […]


Continue.. VLBI Observations of a sample of Palomar-Green quasars II: characterising the parsec-scale radio emission

Edge-Assisted Lightweight Region-of-Interest Extraction and Transmission for Vehicle Perception

Kavli Affiliate: Cheng Peng | First 5 Authors: Yan Cheng, Peng Yang, Ning Zhang, Jiawei Hou, | Summary: To enhance on-road environmental perception for autonomous driving, accurate and real-time analytics on high-resolution video frames generated from on-board cameras be-comes crucial. In this paper, we design a lightweight object location method based on class activation mapping […]


Continue.. Edge-Assisted Lightweight Region-of-Interest Extraction and Transmission for Vehicle Perception

UV-Optical Emission of AB Aur b is Consistent with Scattered Stellar Light

Kavli Affiliate: Gregory J. Herczeg | First 5 Authors: Yifan Zhou, Brendan P. Bowler, Haifeng Yang, Aniket Sanghi, Gregory J. Herczeg | Summary: The proposed protoplanet AB Aur b is a spatially concentrated emission source imaged in the mm-wavelength disk gap of the Herbig Ae/Be star AB Aur. Its near-infrared spectrum and absence of strong […]


Continue.. UV-Optical Emission of AB Aur b is Consistent with Scattered Stellar Light

Determining Quasi-Equilibrium Electron and Hole Distributions from Plasmonic Photocatalysts using Photomodulated X-ray Absorption Spectroscopy

Kavli Affiliate: Scott K. Cushing | First 5 Authors: Levi D. Palmer, Wonseok Lee, Chung Li Dong, Ru-Shi Liu, Nianqiang Wu | Summary: Most photocatalytic and photovoltaic devices operate under broadband, constant illumination. Electron and hole dynamics in these devices, however, are usually measured using ultrafast pulsed lasers in a narrow wavelength range. In this […]


Continue.. Determining Quasi-Equilibrium Electron and Hole Distributions from Plasmonic Photocatalysts using Photomodulated X-ray Absorption Spectroscopy

Overview and First Results of EUSO-SPB2

Kavli Affiliate: Angela V. Olinto | First 5 Authors: Johannes Eser, Angela V. Olinto, Lawrence Wiencke, , | Summary: Observing ultra-high energy cosmic rays (UHECR) and very high energy (VHE) neutrinos from space is a promising way to measure their extremely low fluxes by significantly increasing the observed volume. The Extreme Universe Space Observatory on […]


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Giant elastocaloric effect at low temperatures in TmVO$_4$ and implications for cryogenic cooling

Kavli Affiliate: Brad J. Ramshaw | First 5 Authors: Mark P. Zic, Matthias S. Ikeda, Pierre Massat, Patrick M. Hollister, Linda Ye | Summary: Adiabatic decompression of para-quadrupolar materials has significant potential as a cryogenic cooling technology. We focus on TmVO$_4$, an archetypal material that undergoes a continuous phase transition to a ferroquadrupole-ordered state at […]


Continue.. Giant elastocaloric effect at low temperatures in TmVO$_4$ and implications for cryogenic cooling