EMC holdase:CaV1.2/CaVβ3 complex and CaV1.2 channel structures reveal CaV assembly and drug binding mechanisms

Posted by klaurent UCSF

Kavli Affiliate: Daniel Minor | Authors: Zhou Chen, Abhisek Mondal, Fayal Abderemane-Ali, Jose Montano, Balyn Zaro and Daniel L Minor, Jr. | Summary: Abstract Voltage-gated ion channels (VGICs) comprise multiple structural units whose assembly is required for function1,2. There is scant structural understanding of how VGIC subunits assemble and whether chaperone proteins are required. High-voltage […]


Continue.. EMC holdase:CaV1.2/CaVβ3 complex and CaV1.2 channel structures reveal CaV assembly and drug binding mechanisms

Three-dimensional genome re-wiring in loci with Human Accelerated Regions

Posted by klaurent UCSF

Kavli Affiliate: Alex Pollen | Authors: Kathleen C Keough, Sean Whalen, Fumitaka Inoue, Pawel F Przytycki, Tyler Fair, Chengyu Deng, Marilyn Steyert, Hane Ryu, Kerstin Lindblad-Toh, Elinor Karlsson, Zoonomia Consortium, Tomasz J. Nowakowski, Nadav J. Ahituv, Alex Aaron Pollen and Katherine S Pollard | Summary: Abstract Human Accelerated Regions (HARs) are conserved genomic loci that […]


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Fractional Statistics

Posted by klaurent MIT

Kavli Affiliate: Frank Wilczek | First 5 Authors: Martin Greiter, Frank Wilczek, , , | Summary: The quantum-mechanical description of assemblies of particles whose motion is confined to two (or one) spatial dimensions offers many possibilities that are distinct from bosons and fermions. We call such particles anyons. The simplest anyons are parameterized by an […]


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The Assembly of Black Hole Mass and Luminosity Functions of High-redshift Quasars via Multiple Accretion Episodes

Posted by klaurent Peking

Kavli Affiliate: Kohei Inayoshi | First 5 Authors: Wenxiu Li, Kohei Inayoshi, Masafusa Onoue, Daisuke Toyouchi, | Summary: The early evolution of the quasar luminosity function (QLF) and black hole mass function (BHMF) encodes key information on the physics determining the radiative and accretion processes of supermassive black holes (BHs) in high-$z$ quasars. Although the […]


Continue.. The Assembly of Black Hole Mass and Luminosity Functions of High-redshift Quasars via Multiple Accretion Episodes

The Assembly of Black Hole Mass and Luminosity Functions of High-redshift Quasars via Multiple Accretion Episodes

Posted by klaurent Peking

Kavli Affiliate: Kohei Inayoshi | First 5 Authors: Wenxiu Li, Kohei Inayoshi, Masafusa Onoue, Daisuke Toyouchi, | Summary: The early evolution of the quasar luminosity function (QLF) and black hole mass function (BHMF) encodes key information on the physics determining the radiative and accretion processes of supermassive black holes (BHs) in high-$z$ quasars. Although the […]


Continue.. The Assembly of Black Hole Mass and Luminosity Functions of High-redshift Quasars via Multiple Accretion Episodes

A novel $sqrt{19}timessqrt{19}$ superstructure in epitaxially grown 1T-TaTe$_2$

Posted by klaurent Berkeley

Kavli Affiliate: Michael F. Crommie | First 5 Authors: Jinwoong Hwang, Yeongrok Jin, Canxun Zhang, Tiancong Zhu, Kyoo Kim | Summary: The spontaneous formation of electronic orders is a crucial element for understanding complex quantum states and engineering heterostructures in two-dimensional materials. We report a novel $sqrt{19}timessqrt{19}$ charge order in few-layer thick 1T-TaTe$_2$ transition metal […]


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Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys

Posted by klaurent Hopkins

Kavli Affiliate: Jeremiah Cohen | Authors: Jae Hyung Woo, Claudia G Aguirre, Bilal A Bari, Ken-Ichiro Tsutsui, Fabian Grabenhorst, Jeremiah Y Cohen, Wolfram Schultz, Alicia Izquierdo and Alireza Soltani | Summary: Abstract Despite being unpredictable and uncertain, reward environments often exhibit certain regularities, and animals navigating these environments try to detect and utilize such regularities […]


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A dense $mathbf{0.1 M_{rm odot}}$ star in a 51-minute orbital period eclipsing binary

Posted by klaurent MIT

Kavli Affiliate: Saul Rappaport | First 5 Authors: Kevin B. Burdge, Kareem El-Badry, Thomas R. Marsh, Saul Rappaport, Warren R. Brown | Summary: In over a thousand known cataclysmic variables (CVs), where a white dwarf is accreting from a hydrogen-rich star, only a dozen have orbital periods below 75 minutes. One way to achieve these […]


Continue.. A dense $mathbf{0.1 M_{rm odot}}$ star in a 51-minute orbital period eclipsing binary

X-ray Reverberation Mapping of Ark 564 using Gaussian Process Regression

Posted by klaurent Stanford

Kavli Affiliate: Daniel R. Wilkins | First 5 Authors: Collin D. Lewin, Erin Kara, Daniel R. Wilkins, Guglielmo Mastroserio, Javier A. García | Summary: Ark 564 is an extreme high-Eddington Narrow-line Seyfert 1 galaxy, known for being one of the brightest, most rapidly variable soft X-ray AGN, and for having one of the lowest temperature […]


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A dense $mathbf{0.1 M_{rm odot}}$ star in a 51-minute orbital period eclipsing binary

Posted by klaurent MIT

Kavli Affiliate: Erin Kara | First 5 Authors: Kevin B. Burdge, Kareem El-Badry, Thomas R. Marsh, Saul Rappaport, Warren R. Brown | Summary: In over a thousand known cataclysmic variables (CVs), where a white dwarf is accreting from a hydrogen-rich star, only a dozen have orbital periods below 75 minutes. One way to achieve these […]


Continue.. A dense $mathbf{0.1 M_{rm odot}}$ star in a 51-minute orbital period eclipsing binary