Mef2c Controls Postnatal Callosal Axon Targeting by Regulating Sensitivity to Ephrin Repulsion

Posted by dbos Hopkins

Kavli Affiliate: Alex Kolodkin | Authors: Sriram Sudarsanam, Luis Guzman-Clavel, Nyle Dar, Jakub Ziak, Naseer Shahid, Xinyu O Jin and Alex L Kolodkin | Summary: Cortical connectivity is contingent on ordered emergence of neuron subtypes followed by the formation of subtype-specific axon projections. Intracortical circuits, including long-range callosal projections, are crucial for information processing, but […]


Continue.. Mef2c Controls Postnatal Callosal Axon Targeting by Regulating Sensitivity to Ephrin Repulsion

Loss of the autism associated gene Tbr1 disrupts prediction and encoding by prefrontal ensembles during socioemotional behaviors

Posted by dbos Hopkins

Kavli Affiliate: John Rubenstein and Vikaas Sohal | Authors: Marc Turner, Sarah Robinson-Schwartz, Siavash Fazel Darbandi, John L.R. Rubenstein and Vikaas Singh Sohal | Summary: Disruptions in many genes linked to autism spectrum disorder (ASD) affect synaptic function and socioemotional behaviors in mice. However, exactly how synaptic dysfunction alters neural activity patterns underlying behavior remains […]


Continue.. Loss of the autism associated gene Tbr1 disrupts prediction and encoding by prefrontal ensembles during socioemotional behaviors

BlackTHUNDER — A non-stellar Balmer break in a black hole-dominated little red dot at $z=7.04$

Posted by dbos Cambridge

Kavli Affiliate: Debora Sijacki | First 5 Authors: Xihan Ji, Roberto Maiolino, Hannah Übler, Jan Scholtz, Francesco D’Eugenio | Summary: Recent observations from JWST have revealed an abundant population of active galactic nuclei (AGN) and so-called “Little Red Dots” (LRDs) at $2lesssim z lesssim 11$, many of which are characterized by V-shaped UV-to-optical continua with […]


Continue.. BlackTHUNDER — A non-stellar Balmer break in a black hole-dominated little red dot at $z=7.04$

BlackTHUNDER — A non-stellar Balmer break in a black hole-dominated little red dot at $z=7.04$

Posted by dbos Cambridge

Kavli Affiliate: Debora Sijacki | First 5 Authors: Xihan Ji, Roberto Maiolino, Hannah Übler, Jan Scholtz, Francesco D’Eugenio | Summary: Recent observations from JWST have revealed an abundant population of active galactic nuclei (AGN) and so-called “Little Red Dots” (LRDs) at $2lesssim z lesssim 11$, many of which are characterized by V-shaped UV-to-optical continua with […]


Continue.. BlackTHUNDER — A non-stellar Balmer break in a black hole-dominated little red dot at $z=7.04$

On the equivalence between galaxy angular correlation function and power spectrum in constraining primordial non-Gaussianity

Posted by dbos Tokyo

Kavli Affiliate: Masahiro Takada | First 5 Authors: Ryo Terasawa, Yue Nan, Masahiro Takada, , | Summary: We investigate the angular power spectrum ($C_ell)$ and angular correlation function ($w(theta)$) of galaxy number density field in the presence of the local-type primordial non-Gaussianity (PNG), explicitly accounting for the integral constraint in an all-sky survey. We show […]


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The Intrinsic State Variable in Fundamental Lemma and Its Use in Stability Design for Data-based Control

Posted by dbos UCAS

Kavli Affiliate: Biao Huang | First 5 Authors: Yitao Yan, Jie Bao, Biao Huang, , | Summary: In the data-based setting, analysis and control design of dynamical systems using measured data are typically based on overlapping trajectory segments of the input and output variables. This could lead to complex designs because the system internal dynamics, […]


Continue.. The Intrinsic State Variable in Fundamental Lemma and Its Use in Stability Design for Data-based Control

Introducing the AIDA-TNG project: galaxy formation in alternative dark matter models

Posted by dbos MIT

Kavli Affiliate: Mark Vogelsberger | First 5 Authors: Giulia Despali, Lauro Moscardini, Dylan Nelson, Annalisa Pillepich, Volker Springel | Summary: We introduce the AIDA-TNG project, a suite of cosmological magnetohydrodynamic simulations that simultaneously model galaxy formation and different variations of the underlying dark matter model. We consider the standard cold dark matter model and five […]


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Exploiting Endogenous Cas9-Based Genome Editing of Lacticaseibacillus rhamnosus GG (LGG) for Precision Food Fermentation and Live Biotherapeutics

Posted by dbos Hopkins

Kavli Affiliate: Michael Miller | Authors: Zifan Xie, Yong-Su Jin and Michael J Miller | Summary: Lacticaseibacillus rhamnosus GG (LGG) is one of the most studied probiotic strains and is widely used in both food and therapeutic industries. With its safe and health-beneficial properties, LGG is an ideal candidate for genome modification to enhance its […]


Continue.. Exploiting Endogenous Cas9-Based Genome Editing of Lacticaseibacillus rhamnosus GG (LGG) for Precision Food Fermentation and Live Biotherapeutics

Towards Accurate Unified Anomaly Segmentation

Posted by dbos Berkeley

Kavli Affiliate: Xiang Zhang | First 5 Authors: Wenxin Ma, Qingsong Yao, Xiang Zhang, Zhelong Huang, Zihang Jiang | Summary: Unsupervised anomaly detection (UAD) from images strives to model normal data distributions, creating discriminative representations to distinguish and precisely localize anomalies. Despite recent advancements in the efficient and unified one-for-all scheme, challenges persist in accurately […]


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Time-resolved spectral diffusion of a multimode mechanical memory

Posted by dbos Delft

Kavli Affiliate: Simon Groblacher | First 5 Authors: Niccolò Fiaschi, Lorenzo Scarpelli, Alexander Rolf Korsch, Amirparsa Zivari, Simon Gröblacher | Summary: High-frequency phonons hold great promise as carriers of quantum information on-chip and as quantum memories. Due to their coherent interaction with several systems, their compact mode volume and slow group velocity, multiple experiments have […]


Continue.. Time-resolved spectral diffusion of a multimode mechanical memory