Biological signatures of history: Examination of composite biomes and Y chromosome analysis from da Vinci-associated cultural artifacts

Posted by dbos Rockefeller

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Thomas P. Sakmar | Authors: Harinder Singh, Seesandra V Rajagopala, Rebecca Hart, Pille Hallast, Mark Loftus, Rosana Wiscovitch-Russo, Cody R. K. Conrad, David S Thaler, Guadalupe Piñar, Karina C Åberg, Rosella Lorenzi, Jose A Lorente, Jesse H Ausubel, Thomas P […]


Continue.. Biological signatures of history: Examination of composite biomes and Y chromosome analysis from da Vinci-associated cultural artifacts

SCREWx: A Screwless, Chronic, Recoverable, and Lightweight Neuropixels fixture for freely-moving rodents

Posted by dbos Hopkins

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Kathleen Cullen and James Knierim | Authors: Alexandra Cheng, Tate DeWeese, Yueqing Zhou, Yotaro Sueoka, Sai Koukuntla, Merrill Green, Kathleen Cullen, James Knierim, Austin Graves and Timothy Harris | Summary: High-density Neuropixels probes enable the study of large neural populations […]


Continue.. SCREWx: A Screwless, Chronic, Recoverable, and Lightweight Neuropixels fixture for freely-moving rodents

When and why modular representations emerge

Posted by dbos Columbia

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Stefano Fusi | Authors: W. Jeffrey Johnston and Stefano Fusi | Summary: Experimental and theoretical work has argued both for and against the existence of specialized sub-populations of neurons (modules) within single brain regions. By studying artificial neural networks, we […]


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An orthogonal TRAP enables intersectional genetic access to activated neurons in the mouse brain

Posted by dbos UCSF

Kavli Affiliate: Zachary Knight | Authors: Nikolaos Chatziris, Brooke C Jarvie, Can Liu and Zachary A Knight | Summary: The study of neural circuits has been greatly enabled by methods for obtaining genetic access to activated neurons. However, these approaches typically tag neurons based on their response to only a single stimulus, which limits the […]


Continue.. An orthogonal TRAP enables intersectional genetic access to activated neurons in the mouse brain

Primate ACC encodes natural vocal interactions in a cocktail party

Posted by dbos UCSD / Salk

Endothelial type I interferon signaling modulates the vascular response to ischemic brain injury Kavli Affiliate: Cory Miller | Authors: Arthur Lefevre, Vikram Pal Singh, Timothy Tyree, Jingwen Li, Jean-Rene Duhamel and Cory Miller | Summary: The Cocktail Party Problem (CPP) – extracting meaningful signals amid competing voices – remains poorly understood at the neural level, […]


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Radial-glia-to-astrocyte trans-differentiation and astrocyte transcriptional convergence are coordinated by CEH-43/DLX in C. elegans

Posted by dbos Rockefeller

Kavli Affiliate: Shai Shaham | Authors: Simin Liu, Kenneth Bradley, Jinghong J. Tang, Yoon A. Kim, Ana Milosevic and Shai Shaham | Summary: Mammalian radial glia can remodel to become astrocytes, which acquire common transcriptional states despite spatially and lineally distinct origins. To uncover molecular programs driving convergent radial-glia-to-astrocyte transformation, we investigated development of C. […]


Continue.. Radial-glia-to-astrocyte trans-differentiation and astrocyte transcriptional convergence are coordinated by CEH-43/DLX in C. elegans

Progenitor Diversity and Architecture of the Human Ganglionic Eminences Shaping the Basal Ganglia

Posted by dbos UCSF

Kavli Affiliate: John Rubenstein, Arnold R. Kriegstein, and Arturo Alvarez-Buylla | Authors: Clara V. Siebert, Mengyi Song, Juan A. Moriano, Zhengmeiyu Li, Arantxa Cebrian Silla, Miranda Walker, Songcang Chen, Jennifer Baltazar, Lilian Gomes de Oliveira, Merut Shankar, Yuhan Xie, Pranav Suraparaju, Shaohui Wang, Qiuli Bi, Yajun Xie, Yuqi Ren, Miguel Turrero Garcia, Li Wang, Guolong […]


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Meta-learning is expressed through altered prefrontal cortical dynamics

Posted by dbos UCSF

Kavli Affiliate: Joshua Berke, Loren Frank, and Razi Haque | Authors: Xulu Sun, Alison E. Comrie, Ari E. Kahn, Emily J. Monroe, Abhilasha Joshi, Jennifer A. Guidera, Eric L. Denovellis, Timothy A. Krausz, Jenny Zhou, Paige Thompson, Jose Hernandez, Allison Yorita, Razi Haque, Joshua D. Berke, Nathaniel D. Daw and Loren M. Frankn | Summary: […]


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Extracellular matrix regulates lineage plasticity in prostate cancer through YAP/TEAD

Posted by dbos Rockefeller

Kavli Affiliate: A. James Hudspeth | Authors: Teng Han, Zhen Sun, Matthew Lange, Y Zoe Cho, Patrick Mcgillivray, Maren Buttner, Nathaniel R Kastan, Subhiksha Nandakumar, Huiyong Zhao, Sanyukta Oak, Linda Fong, Wenfei Kang, Ning Fan, Jimmy Zhao, Nazifa Salsabeel, Harmanpreet Kaur, Ninghui Mao, Qing Chang, Eric Rosiek, Eric Chan, Murray Tipping, Nikolaus Schultz, Pierre-Jacques Hamard, […]


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Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant

Posted by dbos Hopkins

Kavli Affiliate: Richard Huganir | Authors: Chih-Ming Chen, Yu-Min Huang, Chih-Ching Chung, Richard C. Johnson, Cheng-Ya Tsai, Yu-Han Chen, Han L. Tan, Fu-Yun Hsiao, Richard L. Huganir and Shu-Ling Chiu | Summary: AMPA receptors (AMPARs) mediate fast excitatory synaptic transmission and are essential for neuronal development and brain function. We investigated the role of a […]


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