The Common Fund Data Ecosystem (CFDE)

Kavli Affiliate: Martin Lindquist | Authors: Julie A. Jurgens, Andreas Bueckle, Jeet Vora, Mano R. Maurya, Taha Mohseni Ahooyi, Erika Zheng, Benjamin Stear, Ding Wang, Caitlin Ree, Srinivasan Ramachandran, Anton Nekrutenko, MacKenzie Brandes, Swathi Thaker, Daniel H. Katz, Monica C. Munoz-Torres, Ido Diamant, Hye-Jung E. Chun, J. Alan Simmons, Sarah K. Tasian, Sherry L. Jenkins, […]


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Acyl-enzyme dynamics, tautomerisation and hydration regulate turnover of carbapenem antibiotics by the OXA-48 β-lactamase

Kavli Affiliate: Michael Beer | Authors: Joseph F Hoff, Michael Beer, Philip Hinchliffe, Catherine L Tooke, Christopher J Schofield, Marc W van der Kamp, Adrian J Mulholland and James Spencer | Summary: OXA-48 is a globally disseminated class D serine β-lactamase that efficiently confers resistance to a range of β-lactam antibiotics, including carbapenems, the most […]


Continue.. Acyl-enzyme dynamics, tautomerisation and hydration regulate turnover of carbapenem antibiotics by the OXA-48 β-lactamase

Learning to select computations in recurrent neural circuits

Kavli Affiliate: Marcelo Mattar | Authors: Sixing Chen, Frederick Callaway, Sreejan Kumar, Shira M. Lupkin, Joni D. Wallis, Vincent B. McGinty, Erin L. Rich and Marcelo G. Mattar | Summary: Two hallmarks of biological computation are its flexibility and efficiency. These features are often attributed to cognitive control processes that balance external utility against computational […]


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Picometer-Scale Spatial Symmetry Breaking in Active Transmissive Metasurfaces

Kavli Affiliate: Harry Atwater | Summary:Active transmissive metasurfaces are central building blocks for future compact, cascadable optical systems, enabling the stacking of multiple functional layers for advanced dynamic beam shaping, photonic neural networks, depth sensing, and holography. We present a transmissive electro-optic metasurface based on silicon-on-lithium-niobate, where an array of silicon waveguides with periodic perturbations, […]


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Las Cumbres Observatory Gravitational-Wave Follow-up in O3 and O4: Strengths and Weaknesses of a Rapid Response Galaxy Targeted Strategy

Kavli Affiliate: Daniel Holz | Summary:We present a summary of gravitational-wave (GW) follow-up using the Las Cumbres Observatory global network of telescopes during the third (O3) and fourth (O4) observing runs of the GW detectors. As in O2, we implemented the Gehrels et al. 2016 galaxy-targeted strategy. Here we test its efficacy in O3 and […]


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Observation of Tunable Superradiant Frequency Combs

Kavli Affiliate: Andrei Faroan | Summary:Cavity quantum electrodynamics (QED) with quantum emitters coupled to resonators provides a powerful platform for engineering light-matter interactions and exploring collective phenomena. In particular, superradiance, arising from collective quantum interference among emitters, has been explored as a route to ultrastable continuous radiation. However, engineering superradiance in the time domain to […]


Continue.. Observation of Tunable Superradiant Frequency Combs

Observation of Tunable Superradiant Frequency Combs

Kavli Affiliate: Andrei Faroan | Summary:Cavity quantum electrodynamics (QED) with quantum emitters coupled to resonators provides a powerful platform for engineering light-matter interactions and exploring collective phenomena. In particular, superradiance, arising from collective quantum interference among emitters, has been explored as a route to ultrastable continuous radiation. However, engineering superradiance in the time domain to […]


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Misaligned circumbinary discs around unequal-mass eccentric binaries: alignment, morphology, and binary accretion variability

Kavli Affiliate: Ruobing Dong | Summary:Binary systems are ubiquitous in the Universe and often host circumbinary discs that are misaligned with the binary orbital plane. Such misalignments can affect disc evolution and binary accretion variability. We here present 3D hydrodynamical simulations of circumbinary discs with initial tilts $i_0$ from $0^circ$ to $180^circ$, around eccentric binaries […]


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An Investigation in the Kinetic Persistence of TiO$_2$ Polymorphs using Machine Learning Driven Pathfinding in Crystal Configuration Space

Kavli Affiliate: Kristin Persson | Summary:As the number of theoretically predicted materials continues to grow, it becomes increasingly important to assess not only their thermodynamic stability but also their kinetic viability under realistic synthesis conditions. In this study, we investigate the hypothesis that the kinetic persistence of a metastable polymorph is related to the topography […]


Continue.. An Investigation in the Kinetic Persistence of TiO$_2$ Polymorphs using Machine Learning Driven Pathfinding in Crystal Configuration Space