Macroscopic Analyses of RNA-Seq Data to Reveal Chromatin Modifications in Aging and Disease

Posted by dbos This Week: Neuroscience, UCSF

Kavli Affiliate: Hana El-Samad | Authors: Achal Mahajan, Francesca Ratti, Ban Wang, Hana El-Samad, James H. Kaufman and Vishrawas Gopalakrishnan | Summary: Regulation of gene expression is fundamental for proper cellular function, and is constrained by the local chromatin environment of each gene, which varies spatially along the chromosome and is shaped by epigenetic modifications. […]


Continue.. Macroscopic Analyses of RNA-Seq Data to Reveal Chromatin Modifications in Aging and Disease

Connecting JWST discovered N/O-enhanced galaxies to globular clusters: Evidence from chemical imprints

Posted by Chicago

Kavli Affiliate: Andrey Kravtsov | First 5 Authors: Xihan Ji, Vasily Belokurov, Roberto Maiolino, Stephanie Monty, Yuki Isobe | Summary: Recent JWST observations have revealed a growing population of galaxies at $z>4$ with elevated nitrogen-to-oxygen ratios. These "N/O-enhanced" galaxies (NOEGs) exhibit near- to super-solar N/O at sub-solar O/H, clearly deviating from the well-established scaling relation […]


Continue.. Connecting JWST discovered N/O-enhanced galaxies to globular clusters: Evidence from chemical imprints