A polymeric, PDMS-based large-scale skull replacement suitable for optical and mechanical access for long-term neuronal imaging, electrophysiology, and optogenetics

Posted by dbos Columbia

Kavli Affiliate: Rafael Yuste | Authors: Kengo Takahashi, Gerhardus Jan Huis in ‘t Veld, Davide Benedetti, Jun-Ying Wang, Samuel Pontes Quero, Rafael Yuste, Cyriel M.A. Pennartz and Umberto Olcese | Summary: Many techniques to record and manipulate neuronal activity across large portions of the vertebrate brain, such as widefield and two-photon calcium imaging, electrophysiology, and […]


Continue.. A polymeric, PDMS-based large-scale skull replacement suitable for optical and mechanical access for long-term neuronal imaging, electrophysiology, and optogenetics

Fast and accessible morphology-free functional fluorescence imaging analysis

Posted by dbos Hopkins

Kavli Affiliate: Kishore V. Kuchibhotla and Adam S. Charles | Authors: Alejandro A Estrada Berlanga, Gabrielle Kang, Amanda Kwok, Thomas Broggini, Jennifer Lawlor, Kishore Kuchibhotla, David Kleninfeld, Gal Mishne and Adam Charles | Summary: Optical calcium imaging is a powerful tool for recording neural activity across a wide range of spatial scales, from dendrites and […]


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Survey of hippocampal responses to sound in naive mice reveals widespread activation by broadband noise onsets

Posted by dbos UCSF

Kavli Affiliate: Andrea Hasenstaub | Authors: James Bigelow, Toshiaki Suzuki, Yulang Wu, Ying Hu and Andrea R Hasenstaub | Summary: Recent studies suggest some hippocampal (HC) neurons respond to passively presented sounds in naive subjects, but the specificity and prevalence of these responses remain unclear. We used Neuropixels probes to record unit activity in HC […]


Continue.. Survey of hippocampal responses to sound in naive mice reveals widespread activation by broadband noise onsets

D3 dopamine receptors implicate a subtype of medium spiny neuron in the aversive effects of antipsychotic medications

Posted by dbos UCSF

Kavli Affiliate: Kevin Bender | Authors: Elinor Lewis, Jessie Muir, Ling C Li, Julianna Glienke, Sarah Warren Gooding, Kevin Bender, Christina Kim and Jennifer Whistler | Summary: Second generation antipsychotics (SGAs) are widely used clinical tools, yet they often cause negative side effects and take weeks to become effective, leading to poor patient compliance. The […]


Continue.. D3 dopamine receptors implicate a subtype of medium spiny neuron in the aversive effects of antipsychotic medications

Evaluating Temporal Plasticity in Foundation Time Series Models for Incremental Fine-tuning

Posted by dbos Tokyo

Kavli Affiliate: Jia Liu | First 5 Authors: Jia Liu, Cheng Jinguo, Xia Fang, Zhenyuan Ma, Yuankai Wu | Summary: Time series foundation models excel at diverse time series forecasting tasks, but their capacity for continuous improvement through incremental learning remains unexplored. We present the first comprehensive study investigating these models’ temporal plasticity – their […]


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Grounding-MD: Grounded Video-language Pre-training for Open-World Moment Detection

Posted by dbos Peking

Kavli Affiliate: Li Xin Li | First 5 Authors: Weijun Zhuang, Qizhang Li, Xin Li, Ming Liu, Xiaopeng Hong | Summary: Temporal Action Detection and Moment Retrieval constitute two pivotal tasks in video understanding, focusing on precisely localizing temporal segments corresponding to specific actions or events. Recent advancements introduced Moment Detection to unify these two […]


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Planet as a Brain: Towards Internet of AgentSites based on AIOS Server

Posted by dbos Berkeley

Kavli Affiliate: Xiang Zhang | First 5 Authors: Xiang Zhang, Yongfeng Zhang, , , | Summary: The internet is undergoing a historical transformation from the "Internet of Websites" to the "Internet of AgentSites." While traditional Websites served as the foundation for information hosting and dissemination, a new frontier is emerging where AgentSites serve as the […]


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Planet as a Brain: Towards Internet of AgentSites based on AIOS Server

Posted by dbos Berkeley

Kavli Affiliate: Xiang Zhang | First 5 Authors: Xiang Zhang, Yongfeng Zhang, , , | Summary: The internet is undergoing a historical transformation from the "Internet of Websites" to the "Internet of AgentSites." While traditional Websites served as the foundation for information hosting and dissemination, a new frontier is emerging where AgentSites serve as the […]


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Mosquito sex under lock and key

Posted by dbos Rockefeller

Kavli Affiliate: Leslie B. Vosshall | Authors: Leah Houri-Zeevi, Madison M. Walker, Jacopo Razzauti, Anurag Sharma, H. Amalia Pasolli and Leslie B. Vosshall | Summary: Female mosquitoes typically mate once in a lifetime, making this singular mating decision critically important for the female. Yet, mosquito mating has been historically viewed as male-guided, with the female […]


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Deep Neural Networks for Modeling Astrophysical Nuclear reacting flows

Posted by Peking

Kavli Affiliate: Lile Wang | First 5 Authors: Xiaoyu Zhang, Yuxiao Yi, Lile Wang, Zhi-Qin John Xu, Tianhan Zhang | Summary: In astrophysical simulations, nuclear reacting flows pose computational challenges due to the stiffness of reaction networks. We introduce neural network-based surrogate models using the DeePODE framework to enhance simulation efficiency while maintaining accuracy and […]


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