Kavli Affiliate: Andrew Baldwin | Summary:Biomolecular condensates composed of intrinsically disordered proteins (IDPs) are vital for proper cellular function, and their dysfunction is associated with diseases including neurodegeneration and cancer. Despite their biological importance, the precise physical mechanisms underlying condensate (dys)function are unclear, in part owing to the difficulties in understanding how biomolecular sequence patterns […]
Continue.. Mesoscopic heterogeneity in biomolecular condensates from sequence patterning