Kavli Affiliate: Lindsay Baker | Authors: Fiona Anne Sargison, Nicolas Cherif Ducrot, Clara Kummerer, Claire Qu, Treasa B O’Hagan, Elliott Haywood, Anju Kudhail, Amy N Moores, Lindsay Baker and Stephan Uphoff | Summary: DNA damage is an important component of the antibacterial response of phagocytes, but which DNA repair mechanisms are active in intracellular bacteria […]

Kavli Affiliate: Becky Carlyle | Authors: Helen A. Jolly, Paula Seghers, Kaleah Balcomb, Amelia J. Smith, Laura Pearson, Ishan Agrawal, Bethany Geary, David A. Bennett, Thomas Wisniewski, Stephanie L. Fowler, Eleanor Drummond, Oliver M. Crook and Becky C. Carlyle | Summary: Proteome-wide analyses of human tissue have transformed our understanding of disease, but provide limited […]

Kavli Affiliate: Andrew Baldwin | Summary: We compare phase-only control with phase-and-amplitude control when designing shaped pulses using the GRAPE algorithm, and explain why phase-only control has significant advantages. Trotterisation can be used to simulate amplitude modulation with phase modulation, indicating that the two approaches are fundamentally equivalent. Pulses designed by either method can be […]

Kavli Affiliate: Andrew Baldwin | Summary: We compare phase-only control with phase-and-amplitude control when designing shaped pulses using the GRAPE algorithm, and explain why phase-only control has significant advantages. Trotterisation can be used to simulate amplitude modulation with phase modulation, indicating that the two approaches are fundamentally equivalent. Pulses designed by either method can be […]

Kavli Affiliate: Andrew Baldwin | Summary: We compare phase-only control with phase-and-amplitude control when designing shaped pulses using the GRAPE algorithm, and explain why phase-only control has significant advantages. Trotterisation can be used to simulate amplitude modulation with phase modulation, indicating that the two approaches are fundamentally equivalent. Pulses designed by either method can be […]

Kavli Affiliate: Zameel Cader | Authors: Xuewei Qi, Alessandra Granata, Tom Van Agtmael, Sanjay Sinha, Zameel Cader, Hugh S Markus, Stuart M. Allan, Karen Horsburgh and Tao Wang | Summary: Cerebral small vessel disease (cSVD) is a major contributor to stroke and cognitive decline, ultimately leading to vascular dementia (VaD). Genetic factors play a key […]

Kavli Affiliate: Stephan Rauschenbach | Summary:Improving the detailed understanding of the underlying properties and functions of biomolecules has recently attracted growing interest, enabled by the possibility of real-space imaging of single, intact macromolecules using Scanning Tunneling Microscopy (STM) in combination with electrospray ion beam deposition and soft landing. This combination provides key insights into biomolecular […]

Kavli Affiliate: Andrew Baldwin | Summary:The universality of quantum theory has been questioned ever since it was proposed. Key to this long-unsolved question is to test whether a given physical system has non-classical features. Here we connect recently proposed witnesses of non-classicality, based on information-theoretic ideas, with the theory of temporal entanglement. We provide a […]

Kavli Affiliate: Justin Benesch | Summary:Size and shape are critical discriminators between molecular species and states. We describe a micro-chip based high-throughput imaging approach offering rapid and precise determination of molecular properties under native solution conditions. Our method detects differences in molecular weight across at least three orders of magnitude, and down to two carbon […]