Extracellular matrix proteolysis maintains synapse plasticity during brain development

Kavli Affiliate: Anna Molofsky and Christoph Kirst | Authors: Haruna Nakajo, Ran Cao, Supriya A. Mula, Justin McKetney, Nicholas J. Silva, Muskaan Shah, Indigo V.L. Rose, Martin Kampmann, Danielle L. Swaney, Christoph Kirst and Anna V. Molofsky | Summary: Maintaining a dynamic neuronal synapse pool is critical to brain development. The extracellular matrix (ECM) regulates […]


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Fundamental Physics and Cosmology with TianQin

Kavli Affiliate: Lijing Shao | Summary:The exploration of the surrounding world and the universe is an important theme in the legacy of humankind. The detection of gravitational waves is adding a new dimension to this grand effort. What are the fundamental physical laws governing the dynamics of the universe? What is the fundamental composition of […]


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Temperature Profiles of Accretion Disks in Luminous Active Galactic Nuclei derived from Ultraviolet Spectroscopic Variability

Kavli Affiliate: Luis C. Ho | First 5 Authors: Suyeon Son, Minjin Kim, Luis C. Ho, , | Summary: The characteristic timescale ($tau$) of continuum variability of the accretion disk in active galactic nuclei (AGNs) is known to be related to the thermal timescale, which is predicted to scale with AGN luminosity ($L$) and restframe […]


Continue.. Temperature Profiles of Accretion Disks in Luminous Active Galactic Nuclei derived from Ultraviolet Spectroscopic Variability

H I absorption line and anomalous dispersion in the radio pulses of PSR B1937+21

Kavli Affiliate: Kejia Lee | Summary:We use the Five-hundred-meter Aperture Spherical radio Telescope to observe the bright millisecond pulsar PSR B1937+21 (J1939+2134) and record the data in the band from 1.0 to 1.5 GHz. We measure the neutral hydrogen (HI) emission and absorption lines near 1420 MHz ($λsimeq 21$ cm). We derive the kinematic distance […]


Continue.. H I absorption line and anomalous dispersion in the radio pulses of PSR B1937+21

A convoy of magnetic millirobots transports endoscopic instruments for minimally-invasive surgery

Kavli Affiliate: Felix Fischer | Summary:Small-scale robots offer significant potential in minimally-invasive medical procedures. Due to the nature of soft biological tissues, however, robots are exposed to complex environments with various challenges in locomotion, which is essential to overcome for useful medical tasks. A single mini-robot often provides insufficient force on slippery biological surfaces to […]


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Data-driven fine-grained region discovery in the mouse brain with transformers

Kavli Affiliate: Reza Abbasi Asl | Authors: Alex Jihun Lee, Shenqin Yao, Nicholas Lusk, Hongkui Zeng, Bosiljka Tasic and Reza Abbasi-Asl | Summary: Spatial transcriptomics offers unique opportunities to define the spatial organization of tissues and organs, such as the mouse brain. We address a key bottleneck in the analysis of organ-scale spatial transcriptomic data […]


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Dopamine D1 receptor expression in prefrontal parvalbumin neurons influences distractibility across species

Kavli Affiliate: Anirvan Nandy | Authors: Mary Kate P Joyce, Tsvetoslav G Ivanov, Fenna Krienen, Jude Mitchell, Shaojie Ma, Wataru Inoue, Anirvan P Nandy, Dibyadeep Datta, Alvaro Duque, Jon I Arellano, Rahul Gupta, Guillermo Gonzalez-Burgos, David A Lewis, Nenad Sestan, Steven A McCarroll, Julio C Martinez-Trujillo, Seán Froudist-Walsh and Amy FT Arnsten | Summary: Marmosets […]


Continue.. Dopamine D1 receptor expression in prefrontal parvalbumin neurons influences distractibility across species

Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C

Kavli Affiliate: Pietro De Camilli and Shawn Ferguson | Authors: Xinbo Wang, Peng Xu, Amanda Bentley-DeSousa, William Hancock-Cerutti, Shujun Cai, Benjamin T Johnson, Francesca Tonelli, Lin Shao, Gabriel Talaia, Dario R Alessi, Shawn M Ferguson and Pietro De Camilli | Summary: Based on genetic studies, lysosome dysfunction is thought to play a pathogenetic role in […]


Continue.. Lysosome damage triggers acute formation of ER to lysosomes membrane tethers mediated by the bridge-like lipid transport protein VPS13C

Epitaxial high-K AlBN barrier GaN HEMTs

Kavli Affiliate: Grace Xing | Summary:We report a polarization-induced 2D electron gas (2DEG) at an epitaxial AlBN/GaN heterojunction grown on a SiC substrate. Using this 2DEG in a long conducting channel, we realize ultra-thin barrier AlBN/GaN high electron mobility transistors that exhibit current densities of more than 0.25 A/mm, clean current saturation, a low pinch-off […]


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Spectroastrometry and Reverberation Mapping of Active Galactic Nuclei. II. Measuring Geometric Distances and Black Hole Masses of Four Nearby Quasars

Kavli Affiliate: Jinyi Shangguan | Summary:The geometric distances of active galactic nuclei (AGNs) are challenging to measure because of their exceptionally compact structure yet vast cosmic distances. A combination of spectroastrometry and reverberation mapping (SARM) of broad-line regions (BLRs) constitutes a novel means to probe the geometric distance of AGNs, which has recently become practically […]


Continue.. Spectroastrometry and Reverberation Mapping of Active Galactic Nuclei. II. Measuring Geometric Distances and Black Hole Masses of Four Nearby Quasars