Kavli Affiliate: Laurent Younes | Authors: An Wang, Stephanie C Hicks, Donald Geman and Laurent Younes | Summary: The selection of marker gene panels is critical for capturing the cellular and spatial heterogeneity in the expanding atlases of single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics data. Most current approaches to marker gene selection operate in […]
Kavli Affiliate: Jing Wang | First 5 Authors: Peng Tang, Jiacheng Liu, Xiaofeng Hou, Yifei Pu, Jing Wang | Summary: The Mixture-of-Experts (MoE) architecture has demonstrated significant advantages in the era of Large Language Models (LLMs), offering enhanced capabilities with reduced inference costs. However, deploying MoE-based LLMs on memoryconstrained edge devices remains challenging due to […]
Kavli Affiliate: Li Xin Li | First 5 Authors: Zhen Cao, F. Aharonian, Axikegu, Y. X. Bai, Y. W. Bao | Summary: The Water Cherenkov Detector Array (WCDA) is one of the components of Large High Altitude Air Shower Observatory (LHAASO) and can monitor any sources over two-thirds of the sky for up to 7 […]
Kavli Affiliate: Scott K. Cushing | First 5 Authors: Levi D. Palmer, Wonseok Lee, Javier Fajardo, Jr., A. Alec Talin, Thomas E. Gage | Summary: Measuring nanoscale local temperatures, particularly in vertically integrated and multi-component systems, remains challenging. Spectroscopic techniques like X-ray absorption and core-loss electron energy-loss spectroscopy (EELS) are sensitive to lattice temperature, but […]
Kavli Affiliate: Giordano Scappucci | First 5 Authors: Marc Botifoll, Ivan Pinto-Huguet, Enzo Rotunno, Thomas Galvani, Catalina Coll | Summary: This article introduces a groundbreaking analytical workflow designed for the holistic characterisation, modelling and physical simulation of device heterostructures. Our innovative workflow autonomously, comprehensively and locally characterises the crystallographic information and 3D orientation of the […]
Kavli Affiliate: Michael Miller | Authors: Mustansir Pindwarawala, Faiyaz A. K. Abid, Jaeeun Lee, Michael L. Miller, Juliet S. Noppers, Andrew P. Rideout and Melina A. Agosto | Summary: Summary: Synaptic transmission from photoreceptors to ON-bipolar cells (BCs) requires the postsynaptic metabotropic glutamate receptor mGluR6, located at BC dendritic tips. Binding of the neurotransmitter glutamate […]
Kavli Affiliate: Alexandra Nelson | Authors: Xiaowen Zhuang, Julia Lemak, Sadhana Sridhar and Alexandra B Nelson | Summary: Summary: Healthy action selection relies on the coordinated activity of striatal direct and indirect pathway neurons. In Parkinson’s disease (PD), in which loss of midbrain dopamine neurons is associated with progressive motor and cognitive deficits, this coordination […]
Kavli Affiliate: Alexandra Nelson | Authors: Emily L Twedell, Chloe J Bair-Marshall, Allison E Girasole, Lara K Scaria, Sadhana Sridhar and Alexandra B Nelson | Summary: Summary: Striatal medium spiny neurons (MSNs) integrate multiple external inputs to shape motor output. In addition, MSNs form local inhibitory synaptic connections with one another. The function of striatal […]
Kavli Affiliate: Scott K. Cushing | First 5 Authors: Jocelyn L. Mendes, Hyun Jun Shin, Jae Yeon Seo, Nara Lee, Young Jai Choi | Summary: Controlling the effects of photoexcited polarons in transition metal oxides can enable the long timescale charge separation necessary for renewable energy applications as well as controlling new quantum phases through […]
Kavli Affiliate: David T. Limmer | First 5 Authors: Robson Christie, Peter G. Bolhuis, David T. Limmer, , | Summary: We study rare transitions in Markovian open quantum systems driven with Gaussian noise, applying transition path and interface sampling methods to trajectories generated by stochastic Schr"odinger dynamics. Interface and path sampling offer insights into rare […]